Hakon Leffler
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- 2019
-
Mark
Structure and Energetics of Ligand–Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides : Insight into Solvation Effects and Multipolar Interactions
(
- Contribution to journal › Article
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Mark
Stereo- And regioselective hydroboration of 1-exo-methylene pyranoses : Discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors
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- Contribution to journal › Article
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Mark
An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade
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- Contribution to journal › Article
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Mark
Letter by Leffler Regarding Article, "Modified Citrus Pectin Prevents Blood-Brain Barrier Disruption in Mouse Subarachnoid Hemorrhage by Inhibiting Galectin-3"
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- Contribution to journal › Letter
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Mark
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
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- Contribution to journal › Article
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Mark
C1-Galactopyranosyl Heterocycle Structure Guides Selectivity : Triazoles Prefer Galectin-1 and Oxazoles Prefer Galectin-3
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- Contribution to journal › Article
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Mark
3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3
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- Contribution to journal › Article
- 2018
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Mark
Different angioregulatory activity of monovalent galectin-9 isoforms
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- Contribution to journal › Article
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Mark
Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain
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- Contribution to journal › Article
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Mark
Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin–glycan specificities in a natural context
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- Contribution to journal › Article
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Mark
Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands
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- Contribution to journal › Article
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Mark
Galectins at a glance
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- Contribution to journal › Article
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Mark
The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin
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- Contribution to journal › Article
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Mark
Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity
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- Contribution to journal › Article
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Mark
Designing interactions by control of protein-ligand complex conformation : Tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions
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- Contribution to journal › Article
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Mark
Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function
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- Contribution to journal › Article
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Mark
Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions
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- Contribution to journal › Article
- 2017
-
Mark
Galectin-3 inhibition by a small-molecule inhibitor reduces both pathological corneal neovascularization and fibrosis
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- Contribution to journal › Article
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Mark
Spindle pole cohesion requires glycosylation-mediated localization of NuMA
(
- Contribution to journal › Article
- 2016
-
Mark
Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3 '-sulfo-lactose, and 2 '-fucosyllactose
(
- Contribution to journal › Article