Advanced

Hand-Arm-Vibration Syndrome (HAVS): Is there a central nervous component? An fMRI study.

Lundborg, Göran LU ; Rosén, Birgitta LU ; Knutsson, Linda LU ; Holtås, Stig LU ; Ståhlberg, Freddy LU and Larsson, Elna-Marie LU (2002) In Journal of Hand Surgery (British Volume) 27(6). p.514-519
Abstract
Hand-held vibrating tools may result in neuromuscular dysfunction and vasospastic problems of the hand. Sensory and motor dysfunction can be explained by injury to peripheral structures, but could also be due to changes in cortical somatotopic mapping of the hand in the brain. The purpose of the present study was to use functional magnetic resonance imaging (fMRI) to assess the somatotopic cortical representation of the hands of workers subjected to occupational vibration. The study included six men with severe vibration exposures who were suffering from hand-arm-vibration syndrome (HAVS) and six controls. The analysis focused on the pattern and degree of activation of contra- and ipsilateral hemispheres of the brain with tactile... (More)
Hand-held vibrating tools may result in neuromuscular dysfunction and vasospastic problems of the hand. Sensory and motor dysfunction can be explained by injury to peripheral structures, but could also be due to changes in cortical somatotopic mapping of the hand in the brain. The purpose of the present study was to use functional magnetic resonance imaging (fMRI) to assess the somatotopic cortical representation of the hands of workers subjected to occupational vibration. The study included six men with severe vibration exposures who were suffering from hand-arm-vibration syndrome (HAVS) and six controls. The analysis focused on the pattern and degree of activation of contra- and ipsilateral hemispheres of the brain with tactile stimulation and motor activation of the hand. These stimulations resulted in well-defined activation of the contralateral, and to a lesser extent the ipsilateral hemisphere. Statistical analysis of this limited patient material did not indicate any significant somatotopic cortical changes following long-term exposure to vibrating hand-held tools, although there was a tendency to a shift of activation towards the more cranial parts of the cortex in the patient group. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Hand Surgery (British Volume)
volume
27
issue
6
pages
514 - 519
publisher
SAGE Publications Inc.
external identifiers
  • pmid:12475506
  • wos:000180016500004
  • scopus:0036909163
ISSN
0266-7681
DOI
10.1054/jhsb.2002.0813
language
English
LU publication?
yes
id
43b4184c-859a-46a8-af4a-642ea27caaac (old id 111427)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12475506&dopt=Abstract
date added to LUP
2007-07-18 14:30:38
date last changed
2017-01-01 07:06:37
@article{43b4184c-859a-46a8-af4a-642ea27caaac,
  abstract     = {Hand-held vibrating tools may result in neuromuscular dysfunction and vasospastic problems of the hand. Sensory and motor dysfunction can be explained by injury to peripheral structures, but could also be due to changes in cortical somatotopic mapping of the hand in the brain. The purpose of the present study was to use functional magnetic resonance imaging (fMRI) to assess the somatotopic cortical representation of the hands of workers subjected to occupational vibration. The study included six men with severe vibration exposures who were suffering from hand-arm-vibration syndrome (HAVS) and six controls. The analysis focused on the pattern and degree of activation of contra- and ipsilateral hemispheres of the brain with tactile stimulation and motor activation of the hand. These stimulations resulted in well-defined activation of the contralateral, and to a lesser extent the ipsilateral hemisphere. Statistical analysis of this limited patient material did not indicate any significant somatotopic cortical changes following long-term exposure to vibrating hand-held tools, although there was a tendency to a shift of activation towards the more cranial parts of the cortex in the patient group.},
  author       = {Lundborg, Göran and Rosén, Birgitta and Knutsson, Linda and Holtås, Stig and Ståhlberg, Freddy and Larsson, Elna-Marie},
  issn         = {0266-7681},
  language     = {eng},
  number       = {6},
  pages        = {514--519},
  publisher    = {SAGE Publications Inc.},
  series       = {Journal of Hand Surgery (British Volume)},
  title        = {Hand-Arm-Vibration Syndrome (HAVS): Is there a central nervous component? An fMRI study.},
  url          = {http://dx.doi.org/10.1054/jhsb.2002.0813},
  volume       = {27},
  year         = {2002},
}