Clinical lacunar syndromes as predictors of lacunar infarcts. A comparison of acute clinical lacunar syndromes and findings on diffusion-weighted MRI
(2000) In Acta Neurologica Scandinavica 101(2). p.128-134- Abstract
- OBJECTIVES: To evaluate if patients with acute lacunar syndromes have acute lacunar infarcts or other types of cerebral lesions on diffusion-weighted MRI. METHODS: Patients with acute lacunar syndromes underwent echo-planar diffusion MRI of the brain within 3 days after stroke onset. Localization and size of lesions with hyperintense signal were determined, compared with clinical characteristics and with findings on follow-up T2-weighted MRI. RESULTS: Twenty-three patients participated in the study. Thirteen patients had pure motor stroke, 1 pure sensory stroke, 8 sensorimotor stroke, and 1 ataxic hemiparesis. Twenty-two patients had at least one lesion with increased signal on diffusion-weighted MR images. These acute lesions were in the... (More)
- OBJECTIVES: To evaluate if patients with acute lacunar syndromes have acute lacunar infarcts or other types of cerebral lesions on diffusion-weighted MRI. METHODS: Patients with acute lacunar syndromes underwent echo-planar diffusion MRI of the brain within 3 days after stroke onset. Localization and size of lesions with hyperintense signal were determined, compared with clinical characteristics and with findings on follow-up T2-weighted MRI. RESULTS: Twenty-three patients participated in the study. Thirteen patients had pure motor stroke, 1 pure sensory stroke, 8 sensorimotor stroke, and 1 ataxic hemiparesis. Twenty-two patients had at least one lesion with increased signal on diffusion-weighted MR images. These acute lesions were in the internal capsule/ basal ganglia/thalamus in 13 patients, subcortical white matter in 5 patients, brainstem in 2 patients, cortex (multiple small lesions) in 1 patient, and cortex + basal ganglia in 1 patient. The median volume of the lesions was 0.6 ml on the initial examination and on follow-up, of 17 patients after 1 to 5 months, 0.5 ml. CONCLUSIONS: Almost all patients with acute ischemic lacunar syndromes have acute lesions on echo-planar diffusion-weighted MRI within 3 days after stroke onset. These lesions are mostly small and subcortical, compatible with lacunar infarcts caused by single penetrating artery occlusion, but in a minor proportion of patients (2 of 23 in our study) a cortical involvement is found. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1117063
- author
- Lindgren, Arne LU ; Staaf, Gert LU ; Geijer, Bo LU ; Brockstedt, Sara LU ; Ståhlberg, Freddy LU ; Holtås, Stig LU and Norrving, Bo LU
- organization
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- diffusion MRI, cerebral infarction, stroke, acute, lacunar syndrome, lacunar infarct
- in
- Acta Neurologica Scandinavica
- volume
- 101
- issue
- 2
- pages
- 128 - 134
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:10685861
- scopus:0033983689
- ISSN
- 1600-0404
- DOI
- 10.1034/j.1600-0404.2000.101002128.x
- language
- English
- LU publication?
- yes
- id
- 8a47b6c5-042e-48ab-832d-4a77d9ed6cc2 (old id 1117063)
- date added to LUP
- 2016-04-01 15:39:06
- date last changed
- 2022-02-12 08:59:52
@article{8a47b6c5-042e-48ab-832d-4a77d9ed6cc2,
abstract = {{OBJECTIVES: To evaluate if patients with acute lacunar syndromes have acute lacunar infarcts or other types of cerebral lesions on diffusion-weighted MRI. METHODS: Patients with acute lacunar syndromes underwent echo-planar diffusion MRI of the brain within 3 days after stroke onset. Localization and size of lesions with hyperintense signal were determined, compared with clinical characteristics and with findings on follow-up T2-weighted MRI. RESULTS: Twenty-three patients participated in the study. Thirteen patients had pure motor stroke, 1 pure sensory stroke, 8 sensorimotor stroke, and 1 ataxic hemiparesis. Twenty-two patients had at least one lesion with increased signal on diffusion-weighted MR images. These acute lesions were in the internal capsule/ basal ganglia/thalamus in 13 patients, subcortical white matter in 5 patients, brainstem in 2 patients, cortex (multiple small lesions) in 1 patient, and cortex + basal ganglia in 1 patient. The median volume of the lesions was 0.6 ml on the initial examination and on follow-up, of 17 patients after 1 to 5 months, 0.5 ml. CONCLUSIONS: Almost all patients with acute ischemic lacunar syndromes have acute lesions on echo-planar diffusion-weighted MRI within 3 days after stroke onset. These lesions are mostly small and subcortical, compatible with lacunar infarcts caused by single penetrating artery occlusion, but in a minor proportion of patients (2 of 23 in our study) a cortical involvement is found.}},
author = {{Lindgren, Arne and Staaf, Gert and Geijer, Bo and Brockstedt, Sara and Ståhlberg, Freddy and Holtås, Stig and Norrving, Bo}},
issn = {{1600-0404}},
keywords = {{diffusion MRI; cerebral infarction; stroke; acute; lacunar syndrome; lacunar infarct}},
language = {{eng}},
number = {{2}},
pages = {{128--134}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Neurologica Scandinavica}},
title = {{Clinical lacunar syndromes as predictors of lacunar infarcts. A comparison of acute clinical lacunar syndromes and findings on diffusion-weighted MRI}},
url = {{http://dx.doi.org/10.1034/j.1600-0404.2000.101002128.x}},
doi = {{10.1034/j.1600-0404.2000.101002128.x}},
volume = {{101}},
year = {{2000}},
}