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Consensus perspectives on prophylactic therapy for haemophilia: summary statement.

Berntorp, Erik LU ; Astermark, Jan LU ; Björkman, S; Blanchette, V. S.; Fischer, K.; Giangrande, P. L. F.; Gringeri, A.; Ljung, Rolf LU ; Manco-Johnson, M. J. and Morfini, M., et al. (2003) In Haemophilia 9(Suppl 1). p.41278-41278
Abstract
Participants in an international conference on prophylactic therapy for severe haemophilia developed a consensus summary of the findings and conclusions of the conference. In the consensus, participants agreed upon revised definitions for primary and secondary prophylaxis and also made recommendations concerning the need for an international system of pharmacovigilance. Considerations on starting prophylaxis, monitoring outcomes, and individualizing treatment regimens were discussed. Several research questions were identified as needing further investigation, including when to start and when to stop prophylaxis, optimal dosing and dose interval, and methods for assessment of long-term treatment effects. Such studies should include... (More)
Participants in an international conference on prophylactic therapy for severe haemophilia developed a consensus summary of the findings and conclusions of the conference. In the consensus, participants agreed upon revised definitions for primary and secondary prophylaxis and also made recommendations concerning the need for an international system of pharmacovigilance. Considerations on starting prophylaxis, monitoring outcomes, and individualizing treatment regimens were discussed. Several research questions were identified as needing further investigation, including when to start and when to stop prophylaxis, optimal dosing and dose interval, and methods for assessment of long-term treatment effects. Such studies should include carefully defined cohorts, validated orthopaedic and quality-of-life assessment instruments, and cost-benefit analyses. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Haemophilia
volume
9
issue
Suppl 1
pages
41278 - 41278
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000182449400001
  • scopus:0042411064
ISSN
1351-8216
DOI
language
English
LU publication?
yes
id
e903cbb0-7ac8-4f3e-be29-4a080038e5ae (old id 113215)
date added to LUP
2007-07-12 12:45:44
date last changed
2018-06-17 03:57:44
@article{e903cbb0-7ac8-4f3e-be29-4a080038e5ae,
  abstract     = {Participants in an international conference on prophylactic therapy for severe haemophilia developed a consensus summary of the findings and conclusions of the conference. In the consensus, participants agreed upon revised definitions for primary and secondary prophylaxis and also made recommendations concerning the need for an international system of pharmacovigilance. Considerations on starting prophylaxis, monitoring outcomes, and individualizing treatment regimens were discussed. Several research questions were identified as needing further investigation, including when to start and when to stop prophylaxis, optimal dosing and dose interval, and methods for assessment of long-term treatment effects. Such studies should include carefully defined cohorts, validated orthopaedic and quality-of-life assessment instruments, and cost-benefit analyses.},
  author       = {Berntorp, Erik and Astermark, Jan and Björkman, S and Blanchette, V. S. and Fischer, K. and Giangrande, P. L. F. and Gringeri, A. and Ljung, Rolf and Manco-Johnson, M. J. and Morfini, M. and Kilcoyne, R. F. and Petrini, P. and Rodriguez-Merchan, E. C. and Schramm, W. and Shapiro, A. and M  Van Den Berg, H. and Hart, C.},
  issn         = {1351-8216},
  language     = {eng},
  number       = {Suppl 1},
  pages        = {41278--41278},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Haemophilia},
  title        = {Consensus perspectives on prophylactic therapy for haemophilia: summary statement.},
  url          = {http://dx.doi.org/},
  volume       = {9},
  year         = {2003},
}