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Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmo Diet and Cancer cohort

Sonestedt, Emily LU orcid ; Ericson, Ulrika LU ; Gullberg, Bo LU ; Penalvo, JL ; Adlercreutz, H and Wirfält, Elisabet LU (2008) In European Journal of Clinical Nutrition 62(8). p.1005-1009
Abstract
Objectives:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies.Subjects and methods:Twenty-six women born between 1940 and 1950 were recruited within the Malmo Diet and Cancer cohort. Three non-fasting and two overnight fasting samples were collected from each individual during a 5-week period. Twenty-one participated in all measurements. Enterolactone concentrations were analyzed by time-resolved fluoroimmunoassay.Results:The within-subject and between-subject variations (coefficient of variations, CV) were estimated to 59 and 89% respectively for fasting samples and... (More)
Objectives:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies.Subjects and methods:Twenty-six women born between 1940 and 1950 were recruited within the Malmo Diet and Cancer cohort. Three non-fasting and two overnight fasting samples were collected from each individual during a 5-week period. Twenty-one participated in all measurements. Enterolactone concentrations were analyzed by time-resolved fluoroimmunoassay.Results:The within-subject and between-subject variations (coefficient of variations, CV) were estimated to 59 and 89% respectively for fasting samples and 71 and 67% for non-fasting samples. The intraclass correlation coefficients (ICC) were estimated to 0.66 (95% confidence interval (CI) 0.35-0.84) for fasting and 0.48 (95% CI, 0.22-0.72) for non-fasting samples.Conclusions:Although the estimated ICC for blood samples was moderate, it indicates that enterolactone levels of both fasting and non-fasting blood samples should be useful in future projects within the Malmo Diet and Cancer cohort.European Journal of Clinical Nutrition advance online publication, 30 May 2007; doi:10.1038/sj.ejcn.1602811. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Clinical Nutrition
volume
62
issue
8
pages
1005 - 1009
publisher
Nature Publishing Group
external identifiers
  • pmid:17538540
  • wos:000258220700010
  • scopus:49349116831
  • pmid:17538540
ISSN
1476-5640
DOI
10.1038/sj.ejcn.1602811
language
English
LU publication?
yes
id
e2941ac8-5578-4328-80b4-57adc935a054 (old id 1141788)
date added to LUP
2016-04-01 14:42:05
date last changed
2022-01-28 02:03:39
@article{e2941ac8-5578-4328-80b4-57adc935a054,
  abstract     = {{Objectives:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies.Subjects and methods:Twenty-six women born between 1940 and 1950 were recruited within the Malmo Diet and Cancer cohort. Three non-fasting and two overnight fasting samples were collected from each individual during a 5-week period. Twenty-one participated in all measurements. Enterolactone concentrations were analyzed by time-resolved fluoroimmunoassay.Results:The within-subject and between-subject variations (coefficient of variations, CV) were estimated to 59 and 89% respectively for fasting samples and 71 and 67% for non-fasting samples. The intraclass correlation coefficients (ICC) were estimated to 0.66 (95% confidence interval (CI) 0.35-0.84) for fasting and 0.48 (95% CI, 0.22-0.72) for non-fasting samples.Conclusions:Although the estimated ICC for blood samples was moderate, it indicates that enterolactone levels of both fasting and non-fasting blood samples should be useful in future projects within the Malmo Diet and Cancer cohort.European Journal of Clinical Nutrition advance online publication, 30 May 2007; doi:10.1038/sj.ejcn.1602811.}},
  author       = {{Sonestedt, Emily and Ericson, Ulrika and Gullberg, Bo and Penalvo, JL and Adlercreutz, H and Wirfält, Elisabet}},
  issn         = {{1476-5640}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{1005--1009}},
  publisher    = {{Nature Publishing Group}},
  series       = {{European Journal of Clinical Nutrition}},
  title        = {{Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmo Diet and Cancer cohort}},
  url          = {{http://dx.doi.org/10.1038/sj.ejcn.1602811}},
  doi          = {{10.1038/sj.ejcn.1602811}},
  volume       = {{62}},
  year         = {{2008}},
}