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Intake of vegetables, legumes, and fruit, and risk for all-cause, cardiovascular, and cancer mortality in a European diabetic population

Noethlings, Ute; Schulze, Matthias B.; Weikert, Cornelia; Boeing, Heiner; van der Schouw, Yvonne T.; Bamia, Christina; Benetou, Vasiliki; Lagiou, Pagona; Krogh, Vittorio and Beulens, Joline W. J., et al. (2008) In Journal of Nutrition 138(4). p.775-781
Abstract
We examined the associations of intake of vegetables, legumes and fruit with all-cause and cause-specific mortality in a population with prevalent diabetes in Europe. A cohort of 10,449 participants with self-reported diabetes within the European Prospective Investigation into Cancer and Nutrition study was followed for a mean of 9 y. Intakes of vegetables, legumes, and fruit were assessed at baseline between 1992 and 2000 using validated country-specific questionnaires. A total of 1346 deaths occurred. Multivariate relative risks (RR) for all-cause mortality were estimated in Cox regression models and FIR for cause-specific mortality were derived in a competing risk model. An increment in intake of total vegetables, legumes, and fruit of... (More)
We examined the associations of intake of vegetables, legumes and fruit with all-cause and cause-specific mortality in a population with prevalent diabetes in Europe. A cohort of 10,449 participants with self-reported diabetes within the European Prospective Investigation into Cancer and Nutrition study was followed for a mean of 9 y. Intakes of vegetables, legumes, and fruit were assessed at baseline between 1992 and 2000 using validated country-specific questionnaires. A total of 1346 deaths occurred. Multivariate relative risks (RR) for all-cause mortality were estimated in Cox regression models and FIR for cause-specific mortality were derived in a competing risk model. An increment in intake of total vegetables, legumes, and fruit of 80 g/d was associated with a RR of death from all causes of 0.94 [95% CI 0.90-0.98]. Analyzed separately, vegetables and legumes were associated with a significantly reduced risk, whereas nonsignificant inverse associations for fruit intake were observed. Cardiovascular disease (CVD) mortality and mortality due to non-CVD/non-cancer causes were significantly inversely associated with intake of total vegetables, legumes, and fruit (RR 0.88 [95% CI 0.81-0.95] and 0.90 [0.82-0.99], respectively) but not cancer mortality 0.08 [0.99-1.17]). Intake of vegetables, legumes, and fruit was associated with reduced risks of all-cause and CVD mortality in a diabetic population. The findings support the current state of evidence from general population studies that the protective potential of vegetable and fruit intake is larger for CVD than for cancer and suggest that diabetes patients may benefit from a diet high in vegetables and fruits. (Less)
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Journal of Nutrition
volume
138
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4
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775 - 781
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American Society for Nutrition
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  • wos:000254138700019
  • scopus:41549144948
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1541-6100
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English
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b95e5014-bcf9-4b86-80d7-a4736c2b83c9 (old id 1184933)
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2008-09-02 14:42:58
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@article{b95e5014-bcf9-4b86-80d7-a4736c2b83c9,
  abstract     = {We examined the associations of intake of vegetables, legumes and fruit with all-cause and cause-specific mortality in a population with prevalent diabetes in Europe. A cohort of 10,449 participants with self-reported diabetes within the European Prospective Investigation into Cancer and Nutrition study was followed for a mean of 9 y. Intakes of vegetables, legumes, and fruit were assessed at baseline between 1992 and 2000 using validated country-specific questionnaires. A total of 1346 deaths occurred. Multivariate relative risks (RR) for all-cause mortality were estimated in Cox regression models and FIR for cause-specific mortality were derived in a competing risk model. An increment in intake of total vegetables, legumes, and fruit of 80 g/d was associated with a RR of death from all causes of 0.94 [95% CI 0.90-0.98]. Analyzed separately, vegetables and legumes were associated with a significantly reduced risk, whereas nonsignificant inverse associations for fruit intake were observed. Cardiovascular disease (CVD) mortality and mortality due to non-CVD/non-cancer causes were significantly inversely associated with intake of total vegetables, legumes, and fruit (RR 0.88 [95% CI 0.81-0.95] and 0.90 [0.82-0.99], respectively) but not cancer mortality 0.08 [0.99-1.17]). Intake of vegetables, legumes, and fruit was associated with reduced risks of all-cause and CVD mortality in a diabetic population. The findings support the current state of evidence from general population studies that the protective potential of vegetable and fruit intake is larger for CVD than for cancer and suggest that diabetes patients may benefit from a diet high in vegetables and fruits.},
  author       = {Noethlings, Ute and Schulze, Matthias B. and Weikert, Cornelia and Boeing, Heiner and van der Schouw, Yvonne T. and Bamia, Christina and Benetou, Vasiliki and Lagiou, Pagona and Krogh, Vittorio and Beulens, Joline W. J. and Peeters, Petra H. M. and Halkjaer, Jytte and Tjonneland, Anne and Tumino, Rosario and Panico, Salvatore and Masala, Giovanna and Clavel-Chapelon, Francoise and de Lauzon, Blandine and Boutron-Ruault, Marie-Christine and Vercambre, Marie-Noel and Kaaks, Rudolf and Linseisen, Jakob and Overvad, Kim and Arriola, Larraitz and Ardanaz, Eva and Gonzalez, Carlos A. and Tormo, Marie-Jose and Bingham, Sheila and Khaw, Kay-Tee and Key, Tim J. A. and Vineis, Paolo and Riboli, Elio and Ferrari, Pietro and Boffetta, Paolo and Bueno-de-Mesquita, H. Bas and van der A, Daphne L. and Berglund, Göran and Wirfält, Elisabet and Hallmans, Göran and Johansson, Ingegerd and Lund, Eiliv and Trichopoulo, Antonia},
  issn         = {1541-6100},
  language     = {eng},
  number       = {4},
  pages        = {775--781},
  publisher    = {American Society for Nutrition},
  series       = {Journal of Nutrition},
  title        = {Intake of vegetables, legumes, and fruit, and risk for all-cause, cardiovascular, and cancer mortality in a European diabetic population},
  volume       = {138},
  year         = {2008},
}