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Blue Chitin columns for the extraction of heterocyclic amines from urine samples

Bång, Joakim LU ; Frandsen, H and Skog, Kerstin LU (2004) In Chromatographia 60(11-12). p.651-655
Abstract
During normal cooking of meat, a class of mutagenic/carcinogenic compounds called heterocyclic amines is formed. Heterocyclic amines are rapidly absorbed and metabolised in the human body, and for estimation of the intake of heterocyclic amines, it is useful to determinate their levels in the urine. Blue Chitin columns were used for the extraction and purification of heterocyclic amines from urine samples spiked with 14 different heterocyclic amines. The samples were analysed using LC-MS. The results show that Blue Chitin columns provide a straightforward and rapid means of extracting heterocyclic amines from urine samples, and that Blue Chitin column are also useful in the purification of urinary metabolites.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Chromatographia
volume
60
issue
11-12
pages
651 - 655
publisher
Vieweg Verlag
external identifiers
  • wos:000225815500008
  • scopus:12144254632
ISSN
0009-5893
DOI
10.1365/s10337-004-0431-5
language
English
LU publication?
yes
id
b5584fcb-9f1d-4d17-b326-634851058aa8 (old id 151401)
date added to LUP
2007-07-18 13:07:09
date last changed
2017-01-01 07:07:37
@article{b5584fcb-9f1d-4d17-b326-634851058aa8,
  abstract     = {During normal cooking of meat, a class of mutagenic/carcinogenic compounds called heterocyclic amines is formed. Heterocyclic amines are rapidly absorbed and metabolised in the human body, and for estimation of the intake of heterocyclic amines, it is useful to determinate their levels in the urine. Blue Chitin columns were used for the extraction and purification of heterocyclic amines from urine samples spiked with 14 different heterocyclic amines. The samples were analysed using LC-MS. The results show that Blue Chitin columns provide a straightforward and rapid means of extracting heterocyclic amines from urine samples, and that Blue Chitin column are also useful in the purification of urinary metabolites.},
  author       = {Bång, Joakim and Frandsen, H and Skog, Kerstin},
  issn         = {0009-5893},
  language     = {eng},
  number       = {11-12},
  pages        = {651--655},
  publisher    = {Vieweg Verlag},
  series       = {Chromatographia},
  title        = {Blue Chitin columns for the extraction of heterocyclic amines from urine samples},
  url          = {http://dx.doi.org/10.1365/s10337-004-0431-5},
  volume       = {60},
  year         = {2004},
}