G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.
Broselid, Stefan LU ; Cheng, Benxu ; Sjöström, Martin LU ; Lövgren, Kristina LU ; Klug-De Santiago, Heather L P ; Belting, Mattias LU ; Jirström, Karin LU
; Malmström, Per
LU
; Olde, Björn
LU
and Bendahl, Pär-Ola
LU
, et al.
(2013)
In Clinical Cancer Research
19(7).
p.1681-1692
- Abstract
- G protein-coupled estrogen receptor 1 (GPER1), previously named GPR30, is a membrane receptor reported to mediate nongenomic estrogen responses. We investigated if GPER1 expression correlates with any clinicopathologic variables and distant disease-free survival (DDFS) in patients with breast cancer, if any prognostic impact of the receptor is dependent on estrogen receptor-α (ER-α) status, and if the receptor impacts apoptotic signaling in ER-positive breast cancer cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3734200
- author
- Broselid, Stefan
LU
; Cheng, Benxu
; Sjöström, Martin
LU
; Lövgren, Kristina
LU
; Klug-De Santiago, Heather L P
; Belting, Mattias
LU
; Jirström, Karin
LU
; Malmström, Per
LU
; Olde, Björn
LU
and Bendahl, Pär-Ola
LU
, et al. (More)
- Broselid, Stefan
LU
; Cheng, Benxu
; Sjöström, Martin
LU
; Lövgren, Kristina
LU
; Klug-De Santiago, Heather L P
; Belting, Mattias
LU
; Jirström, Karin
LU
; Malmström, Per
LU
; Olde, Björn
LU
; Bendahl, Pär-Ola
LU
; Werner Hartman, Linda
LU
; Fernö, Mårten
LU
and Leeb-Lundberg, Fredrik
LU
(Less)
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Cancer Research
- volume
- 19
- issue
- 7
- pages
- 1681 - 1692
- publisher
- American Association for Cancer Research
- external identifiers
-
- wos:000316996900008
- pmid:23554355
- scopus:84877088406
- pmid:23554355
- ISSN
- 1078-0432
- DOI
- 10.1158/1078-0432.CCR-12-2376
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Cancer Epidemiology (013007100), Oncology, MV (013035000), Department of Experimental Medical Science (013210000), Cardiology (013230026), Pathology, (Lund) (013030000), Drug Target Discovery (013212045)
- id
- 0c5895c1-f055-46d6-8583-248b37d9ace7 (old id 3734200)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23554355?dopt=Abstract
- date added to LUP
- 2016-04-01 10:51:42
- date last changed
- 2024-02-22 12:36:24
@article{0c5895c1-f055-46d6-8583-248b37d9ace7,
abstract = {{G protein-coupled estrogen receptor 1 (GPER1), previously named GPR30, is a membrane receptor reported to mediate nongenomic estrogen responses. We investigated if GPER1 expression correlates with any clinicopathologic variables and distant disease-free survival (DDFS) in patients with breast cancer, if any prognostic impact of the receptor is dependent on estrogen receptor-α (ER-α) status, and if the receptor impacts apoptotic signaling in ER-positive breast cancer cells.}},
author = {{Broselid, Stefan and Cheng, Benxu and Sjöström, Martin and Lövgren, Kristina and Klug-De Santiago, Heather L P and Belting, Mattias and Jirström, Karin and Malmström, Per and Olde, Björn and Bendahl, Pär-Ola and Werner Hartman, Linda and Fernö, Mårten and Leeb-Lundberg, Fredrik}},
issn = {{1078-0432}},
language = {{eng}},
number = {{7}},
pages = {{1681--1692}},
publisher = {{American Association for Cancer Research}},
series = {{Clinical Cancer Research}},
title = {{G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.}},
url = {{http://dx.doi.org/10.1158/1078-0432.CCR-12-2376}},
doi = {{10.1158/1078-0432.CCR-12-2376}},
volume = {{19}},
year = {{2013}},
}