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Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.

Knutsson, Linda LU ; Lind, Emelie LU ; Ahlgren, André LU ; van Osch, Matthias J P; Markenroth Bloch, Karin LU ; Surova, Yulia LU ; Ståhlberg, Freddy LU ; van Westen, Danielle LU and Wirestam, Ronnie LU (2014) In Magnetic Resonance in Medicine 72(4). p.996-1006
Abstract
Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Magnetic Resonance in Medicine
volume
72
issue
4
pages
996 - 1006
publisher
Wiley Online Library
external identifiers
  • pmid:24285621
  • wos:000342342300011
  • scopus:84927691578
ISSN
1522-2594
DOI
10.1002/mrm.25006
language
English
LU publication?
yes
id
32109d43-6c9b-45bd-8c15-af57a9b3ff84 (old id 4178815)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24285621?dopt=Abstract
date added to LUP
2013-12-02 18:09:41
date last changed
2017-06-11 03:10:08
@article{32109d43-6c9b-45bd-8c15-af57a9b3ff84,
  abstract     = {Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.},
  author       = {Knutsson, Linda and Lind, Emelie and Ahlgren, André and van Osch, Matthias J P and Markenroth Bloch, Karin and Surova, Yulia and Ståhlberg, Freddy and van Westen, Danielle and Wirestam, Ronnie},
  issn         = {1522-2594},
  language     = {eng},
  number       = {4},
  pages        = {996--1006},
  publisher    = {Wiley Online Library},
  series       = {Magnetic Resonance in Medicine},
  title        = {Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.},
  url          = {http://dx.doi.org/10.1002/mrm.25006},
  volume       = {72},
  year         = {2014},
}