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Tea and coffee consumption and risk of esophageal cancer: The European prospective investigation into cancer and nutrition study

Zamora-Ros, Raul; Lujan-Barroso, Leila; Bueno-de-Mesquita, H. B(as); Dik, Vincent K.; Boeing, Heiner; Steffen, Annika; Tjonneland, Anne; Olsen, Anja; Bech, Bodil Hammer and Overvad, Kim, et al. (2014) In International Journal of Cancer 135(6). p.1470-1479
Abstract
Epidemiological data regarding tea and coffee consumption and risk of esophageal cancer (EC) is still inconclusive. We examined the association of tea and coffee consumption with EC risk among 442,143 men and women without cancer at baseline from 9 countries of the European Prospective Investigation into Cancer and Nutrition. Tea and coffee intakes were recorded using country-specific validated dietary questionnaires. Cox regression models were used to analyze the relationships between tea and coffee intake and EC risk. During a mean follow-up of 11.1 years, 339 participants developed EC, of which 142 were esophageal adenocarcinoma (EAC) and 174 were esophageal squamous cell carcinoma (ESCC). In the multivariable models, no significant... (More)
Epidemiological data regarding tea and coffee consumption and risk of esophageal cancer (EC) is still inconclusive. We examined the association of tea and coffee consumption with EC risk among 442,143 men and women without cancer at baseline from 9 countries of the European Prospective Investigation into Cancer and Nutrition. Tea and coffee intakes were recorded using country-specific validated dietary questionnaires. Cox regression models were used to analyze the relationships between tea and coffee intake and EC risk. During a mean follow-up of 11.1 years, 339 participants developed EC, of which 142 were esophageal adenocarcinoma (EAC) and 174 were esophageal squamous cell carcinoma (ESCC). In the multivariable models, no significant associations between tea (mostly black tea), and coffee intake and risk of EC, EAC and ESCC were observed. In stratified analyses, among men coffee consumption was inversely related to ESCC (HR for comparison of extreme tertiles 0.42, 95% CI 0.20-0.88; p-trend = 0.022), but not among women. In current smokers, a significant and inverse association was observed between ESCC risk and tea (HR 0.46, 95% CI 0.23-0.93; p-trend = 0.053) and coffee consumption (HR 0.37, 95% CI 0.19-0.73; p-trend = 0.011). However, no statistically significant findings were observed using the continuous variable (per 100 mL/d). These data did not show a significant association between tea and coffee consumption and EC, EAC and ESCC, although a decreased risk of ESCC among men and current smokers is suggested, but need to be confirmed in further prospective studies including more cases. (Less)
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published
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keywords
tea, coffee, esophageal cancer, smoking status, EPIC
in
International Journal of Cancer
volume
135
issue
6
pages
1470 - 1479
publisher
John Wiley & Sons
external identifiers
  • wos:000339269100020
  • scopus:84904068436
ISSN
0020-7136
DOI
10.1002/ijc.28789
language
English
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yes
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0e6b1c83-3765-4075-b175-e8e1a6482afb (old id 4591753)
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2014-09-04 14:45:11
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2017-10-22 03:02:02
@article{0e6b1c83-3765-4075-b175-e8e1a6482afb,
  abstract     = {Epidemiological data regarding tea and coffee consumption and risk of esophageal cancer (EC) is still inconclusive. We examined the association of tea and coffee consumption with EC risk among 442,143 men and women without cancer at baseline from 9 countries of the European Prospective Investigation into Cancer and Nutrition. Tea and coffee intakes were recorded using country-specific validated dietary questionnaires. Cox regression models were used to analyze the relationships between tea and coffee intake and EC risk. During a mean follow-up of 11.1 years, 339 participants developed EC, of which 142 were esophageal adenocarcinoma (EAC) and 174 were esophageal squamous cell carcinoma (ESCC). In the multivariable models, no significant associations between tea (mostly black tea), and coffee intake and risk of EC, EAC and ESCC were observed. In stratified analyses, among men coffee consumption was inversely related to ESCC (HR for comparison of extreme tertiles 0.42, 95% CI 0.20-0.88; p-trend = 0.022), but not among women. In current smokers, a significant and inverse association was observed between ESCC risk and tea (HR 0.46, 95% CI 0.23-0.93; p-trend = 0.053) and coffee consumption (HR 0.37, 95% CI 0.19-0.73; p-trend = 0.011). However, no statistically significant findings were observed using the continuous variable (per 100 mL/d). These data did not show a significant association between tea and coffee consumption and EC, EAC and ESCC, although a decreased risk of ESCC among men and current smokers is suggested, but need to be confirmed in further prospective studies including more cases.},
  author       = {Zamora-Ros, Raul and Lujan-Barroso, Leila and Bueno-de-Mesquita, H. B(as) and Dik, Vincent K. and Boeing, Heiner and Steffen, Annika and Tjonneland, Anne and Olsen, Anja and Bech, Bodil Hammer and Overvad, Kim and Boutron-Ruault, Marie-Christine and Racine, Antoine and Fagherazzi, Guy and Kuhn, Tilman and Katzke, Verena and Trichopoulou, Antonia and Lagiou, Pagona and Trichopoulos, Dimitrios and Tumino, Rosario and Panico, Salvatore and Vineis, Paolo and Grioni, Sara and Palli, Domenico and Weiderpass, Elisabete and Skeie, Guri and Maria Huerta, Jose and Sanchez, Maria-Jose and Argueelles, Marcial and Amiano, Pilar and Ardanaz, Eva and Nilsson, Lena and Wallner, Bengt and Lindkvist, Bjorn and Wallström, Peter and Peeters, Petra H. M. and Key, Timothy J. and Khaw, Kay-Thee and Wareham, Nicholas J. and Freisling, Heinz and Stepien, Magdalena and Ferrari, Pietro and Gunter, Marc J. and Murphy, Neil and Riboli, Elio and Gonzalez, Carlos A.},
  issn         = {0020-7136},
  keyword      = {tea,coffee,esophageal cancer,smoking status,EPIC},
  language     = {eng},
  number       = {6},
  pages        = {1470--1479},
  publisher    = {John Wiley & Sons},
  series       = {International Journal of Cancer},
  title        = {Tea and coffee consumption and risk of esophageal cancer: The European prospective investigation into cancer and nutrition study},
  url          = {http://dx.doi.org/10.1002/ijc.28789},
  volume       = {135},
  year         = {2014},
}