Microchannel Acoustophoresis does not Impact Survival or Function of Microglia, Leukocytes or Tumor Cells.
(2013) In PLoS ONE 8(5).- Abstract
- The use of acoustic forces to manipulate particles or cells at the microfluidic scale (i.e. acoustophoresis), enables non-contact, label-free separation based on intrinsic cell properties such as size, density and compressibility. Acoustophoresis holds great promise as a cell separation technique in several research and clinical areas. However, it has been suggested that the force acting upon cells undergoing acoustophoresis may impact cell viability, proliferation or cell function via subtle phenotypic changes. If this were the case, it would suggest that the acoustophoresis method would be a less useful tool for many cell analysis applications as well as for cell therapy.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3913833
- author
- organization
-
- Department of Experimental Medical Science
- Basal Ganglia Pathophysiology (research group)
- Clinical Chemistry, Malmö (research group)
- Department of Biomedical Engineering
- Clinical Physiology (Lund)
- Clinical Neurophysiology
- Neuroinflammation (research group)
- EpiHealth: Epidemiology for Health
- MultiPark: Multidisciplinary research focused on Parkinson´s disease
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 8
- issue
- 5
- article number
- e64233
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000319738100022
- pmid:23724038
- scopus:84878281766
- pmid:23724038
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0064233
- language
- English
- LU publication?
- yes
- id
- 57b725b7-38e2-4460-a9c2-3b9705b5b825 (old id 3913833)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23724038?dopt=Abstract
- date added to LUP
- 2016-04-01 13:04:33
- date last changed
- 2024-01-09 06:49:14
@article{57b725b7-38e2-4460-a9c2-3b9705b5b825, abstract = {{The use of acoustic forces to manipulate particles or cells at the microfluidic scale (i.e. acoustophoresis), enables non-contact, label-free separation based on intrinsic cell properties such as size, density and compressibility. Acoustophoresis holds great promise as a cell separation technique in several research and clinical areas. However, it has been suggested that the force acting upon cells undergoing acoustophoresis may impact cell viability, proliferation or cell function via subtle phenotypic changes. If this were the case, it would suggest that the acoustophoresis method would be a less useful tool for many cell analysis applications as well as for cell therapy.}}, author = {{Burguillos Garcia, Miguel and Magnusson, Cecilia and Nordin, Maria and Lenshof, Andreas and Augustsson, Per and Hansson, Magnus and Elmer, Eskil and Lilja, Hans and Brundin, Patrik and Laurell, Thomas and Deierborg, Tomas}}, issn = {{1932-6203}}, language = {{eng}}, number = {{5}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{Microchannel Acoustophoresis does not Impact Survival or Function of Microglia, Leukocytes or Tumor Cells.}}, url = {{https://lup.lub.lu.se/search/files/3145369/4067568.pdf}}, doi = {{10.1371/journal.pone.0064233}}, volume = {{8}}, year = {{2013}}, }