Association of Ultra-Processed Food Intake with Cardiovascular And Respiratory Disease Multimorbidity : A Prospective Cohort Study
(2023) In Molecular Nutrition & Food Research 67(11).- Abstract
SCOPE: Evidence suggests a positive association between ultra-processed food (UPF) consumption and the incidence of cardiovascular disease (CVD). We aimed to investigate associations between UPF intake and respiratory disease, CVD, and their multimorbidity in a large prospective cohort.
METHODS AND RESULTS: Within the UK Biobank, participants who were free from respiratory disease or CVD at baseline and completed at least two times 24-h dietary records were included in this study. After adjusting for socioeconomic status and lifestyle factors, the hazard ratios (95% confidence interval) for each ten percent increase in UPF were 1.06 (1.04, 1.09) for CVD, 1.04 (1.02, 1.06) for respiratory disease, 1.15 (1.08, 1.22) for CVD... (More)
SCOPE: Evidence suggests a positive association between ultra-processed food (UPF) consumption and the incidence of cardiovascular disease (CVD). We aimed to investigate associations between UPF intake and respiratory disease, CVD, and their multimorbidity in a large prospective cohort.
METHODS AND RESULTS: Within the UK Biobank, participants who were free from respiratory disease or CVD at baseline and completed at least two times 24-h dietary records were included in this study. After adjusting for socioeconomic status and lifestyle factors, the hazard ratios (95% confidence interval) for each ten percent increase in UPF were 1.06 (1.04, 1.09) for CVD, 1.04 (1.02, 1.06) for respiratory disease, 1.15 (1.08, 1.22) for CVD mortality, and 1.06 (1.01, 1.12) for their multimorbidity, respectively. In addition, replacing 20% of UPF weight in diet with an equivalent proportion of unprocessed or minimally processed foods was estimated to be associated with 11% lower risk of CVD, 7% lower risk of respiratory disease, 25% lower risk of CVD mortality and 11% lower risk of CVD and respiratory disease multimorbidity.
CONCLUSION: In this prospective cohort study, higher consumption of UPF was associated with higher risks of CVD and respiratory disease multimorbidity. Further longitudinal studies are needed to confirm our findings. This article is protected by copyright. All rights reserved.
(Less)
- author
- Li, Huiping LU ; Li, Shu ; Yang, Hongxi ; Zhang, Yuan ; Ma, Yue ; Hou, Yabing ; Zhang, Xinyu ; Sun, Li ; Borné, Yan LU and Wang, Yaogang
- organization
- publishing date
- 2023-03-17
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Molecular Nutrition & Food Research
- volume
- 67
- issue
- 11
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:36932667
- scopus:85152959726
- ISSN
- 1613-4133
- DOI
- 10.1002/mnfr.202200628
- language
- English
- LU publication?
- yes
- additional info
- This article is protected by copyright. All rights reserved.
- id
- 741cdcd0-c7cd-45f9-b6d6-371ac8196347
- date added to LUP
- 2023-03-25 08:03:15
- date last changed
- 2024-04-19 20:32:59
@article{741cdcd0-c7cd-45f9-b6d6-371ac8196347,
abstract = {{<p>SCOPE: Evidence suggests a positive association between ultra-processed food (UPF) consumption and the incidence of cardiovascular disease (CVD). We aimed to investigate associations between UPF intake and respiratory disease, CVD, and their multimorbidity in a large prospective cohort.</p><p>METHODS AND RESULTS: Within the UK Biobank, participants who were free from respiratory disease or CVD at baseline and completed at least two times 24-h dietary records were included in this study. After adjusting for socioeconomic status and lifestyle factors, the hazard ratios (95% confidence interval) for each ten percent increase in UPF were 1.06 (1.04, 1.09) for CVD, 1.04 (1.02, 1.06) for respiratory disease, 1.15 (1.08, 1.22) for CVD mortality, and 1.06 (1.01, 1.12) for their multimorbidity, respectively. In addition, replacing 20% of UPF weight in diet with an equivalent proportion of unprocessed or minimally processed foods was estimated to be associated with 11% lower risk of CVD, 7% lower risk of respiratory disease, 25% lower risk of CVD mortality and 11% lower risk of CVD and respiratory disease multimorbidity.</p><p>CONCLUSION: In this prospective cohort study, higher consumption of UPF was associated with higher risks of CVD and respiratory disease multimorbidity. Further longitudinal studies are needed to confirm our findings. This article is protected by copyright. All rights reserved.</p>}},
author = {{Li, Huiping and Li, Shu and Yang, Hongxi and Zhang, Yuan and Ma, Yue and Hou, Yabing and Zhang, Xinyu and Sun, Li and Borné, Yan and Wang, Yaogang}},
issn = {{1613-4133}},
language = {{eng}},
month = {{03}},
number = {{11}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Molecular Nutrition & Food Research}},
title = {{Association of Ultra-Processed Food Intake with Cardiovascular And Respiratory Disease Multimorbidity : A Prospective Cohort Study}},
url = {{http://dx.doi.org/10.1002/mnfr.202200628}},
doi = {{10.1002/mnfr.202200628}},
volume = {{67}},
year = {{2023}},
}