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Intraneural edema following exposure to vibration

Lundborg, G LU ; Dahlin, L B LU ; Danielsen, N LU ; Hansson, H A; Necking, L E LU and Pyykkö, I. (1987) In Scandinavian Journal of Work, Environment and Health 13(4). p.9-326
Abstract

Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an... (More)

Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an important pathophysiological factor in the occurrence of vibration-induced neuropathy.

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organization
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Contribution to journal
publication status
published
subject
keywords
Animals, Edema, Horseradish Peroxidase, Rats, Rats, Inbred Strains, Sciatic Nerve, Vascular Diseases, Vibration, Journal Article, Research Support, Non-U.S. Gov't
in
Scandinavian Journal of Work, Environment and Health
volume
13
issue
4
pages
4 pages
publisher
Finnish Institute of Occupational Health
external identifiers
  • scopus:0023226713
ISSN
0355-3140
language
English
LU publication?
yes
id
764d435e-0aa6-4c98-8b33-71fa07e41872
date added to LUP
2017-10-13 14:07:31
date last changed
2017-11-13 15:06:18
@article{764d435e-0aa6-4c98-8b33-71fa07e41872,
  abstract     = {<p>Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an important pathophysiological factor in the occurrence of vibration-induced neuropathy.</p>},
  author       = {Lundborg, G and Dahlin, L B and Danielsen, N and Hansson, H A and Necking, L E and Pyykkö, I.},
  issn         = {0355-3140},
  keyword      = {Animals,Edema,Horseradish Peroxidase,Rats,Rats, Inbred Strains,Sciatic Nerve,Vascular Diseases,Vibration,Journal Article,Research Support, Non-U.S. Gov't},
  language     = {eng},
  number       = {4},
  pages        = {9--326},
  publisher    = {Finnish Institute of Occupational Health},
  series       = {Scandinavian Journal of Work, Environment and Health},
  title        = {Intraneural edema following exposure to vibration},
  volume       = {13},
  year         = {1987},
}