Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum.
(2015) In BMC Research Notes 8(1).- Abstract
- The gonadotropin-releasing hormone (GnRH) analog buserelin causes enteric neuronal loss. Acute stress or injection of corticotropin-releasing factor (CRF) affects motility, secretion, and barrier function of the gastrointestinal tract. The aim of the study was to characterize the CRF immunoreactivity in enteric neurons after buserelin treatment, and to evaluate possible effects of enteric neuropathy on gut microbiota, intestinal permeability, and stress response behavior.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8500358
- author
- Sand, Elin LU ; Linninge, Caroline LU ; Lozinska, Liudmyla ; Egecioglu, Emil ; Roth, Bodil LU ; Molin, Göran ; Weström, Björn ; Ekblad, Eva LU and Ohlsson, Bodil LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Research Notes
- volume
- 8
- issue
- 1
- article number
- 824
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26710832
- scopus:84955395423
- pmid:26710832
- ISSN
- 1756-0500
- DOI
- 10.1186/s13104-015-1800-x
- language
- English
- LU publication?
- yes
- id
- 0729119f-be87-460c-a2be-47a26630ceb6 (old id 8500358)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26710832?dopt=Abstract
- date added to LUP
- 2016-04-04 09:37:52
- date last changed
- 2023-11-01 13:57:11
@article{0729119f-be87-460c-a2be-47a26630ceb6, abstract = {{The gonadotropin-releasing hormone (GnRH) analog buserelin causes enteric neuronal loss. Acute stress or injection of corticotropin-releasing factor (CRF) affects motility, secretion, and barrier function of the gastrointestinal tract. The aim of the study was to characterize the CRF immunoreactivity in enteric neurons after buserelin treatment, and to evaluate possible effects of enteric neuropathy on gut microbiota, intestinal permeability, and stress response behavior.}}, author = {{Sand, Elin and Linninge, Caroline and Lozinska, Liudmyla and Egecioglu, Emil and Roth, Bodil and Molin, Göran and Weström, Björn and Ekblad, Eva and Ohlsson, Bodil}}, issn = {{1756-0500}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{BMC Research Notes}}, title = {{Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum.}}, url = {{http://dx.doi.org/10.1186/s13104-015-1800-x}}, doi = {{10.1186/s13104-015-1800-x}}, volume = {{8}}, year = {{2015}}, }