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Bioactive peptides as functional food ingredients: Production, mechanisms of action, market trends, and future perspectives with emphasis on andean crops

Ibieta, Gabriela LU ; Ortiz-Sempértegui, Jimena LU ; Peñarrieta, J. Mauricio and Linares-Pastén, Javier A. LU orcid (2025) In Journal of Functional Foods 135.
Abstract
The development of bioactive peptides is of great interest in the food and pharmaceutical industries because of their positive impact on health. However, peptide's bioavailability depends on their stability along the gastrointestinal tract and their ability to be transported to targets located in peripheral organs, whose mechanisms are still poorly understood. However, several studies, mainly in vitro and in vivo, have shown antimicrobial, antitumoral, antihypertensive, anti-inflammatory, antidiabetic, and antioxidative effects. Indeed, some bioactive peptides are already on the global market. One of the current and future perspectives includes the development of novel bioactive peptides from food plant proteins. In this regard, some... (More)
The development of bioactive peptides is of great interest in the food and pharmaceutical industries because of their positive impact on health. However, peptide's bioavailability depends on their stability along the gastrointestinal tract and their ability to be transported to targets located in peripheral organs, whose mechanisms are still poorly understood. However, several studies, mainly in vitro and in vivo, have shown antimicrobial, antitumoral, antihypertensive, anti-inflammatory, antidiabetic, and antioxidative effects. Indeed, some bioactive peptides are already on the global market. One of the current and future perspectives includes the development of novel bioactive peptides from food plant proteins. In this regard, some grains and seeds, such as quinoa, maize, cañihua and tarwi, which were domesticated in the Andes, are attracting global interest due to their high nutritional value and potential as a source of novel bioactive peptides. Tarwi stands out for its high protein content compared to other legumes. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Novel bioactive peptides, Food plant peptides, Nutraceutical peptides, ndean food plants, Peptides production
in
Journal of Functional Foods
volume
135
article number
107109
pages
15 pages
publisher
Elsevier
ISSN
1756-4646
DOI
10.1016/j.jff.2025.107109
language
English
LU publication?
yes
id
c4234640-b85d-4755-830b-9c1320414165
date added to LUP
2025-11-22 22:19:17
date last changed
2025-12-01 12:43:57
@article{c4234640-b85d-4755-830b-9c1320414165,
  abstract     = {{The development of bioactive peptides is of great interest in the food and pharmaceutical industries because of their positive impact on health. However, peptide's bioavailability depends on their stability along the gastrointestinal tract and their ability to be transported to targets located in peripheral organs, whose mechanisms are still poorly understood. However, several studies, mainly in vitro and in vivo, have shown antimicrobial, antitumoral, antihypertensive, anti-inflammatory, antidiabetic, and antioxidative effects. Indeed, some bioactive peptides are already on the global market. One of the current and future perspectives includes the development of novel bioactive peptides from food plant proteins. In this regard, some grains and seeds, such as quinoa, maize, cañihua and tarwi, which were domesticated in the Andes, are attracting global interest due to their high nutritional value and potential as a source of novel bioactive peptides. Tarwi stands out for its high protein content compared to other legumes.}},
  author       = {{Ibieta, Gabriela and Ortiz-Sempértegui, Jimena and Peñarrieta, J. Mauricio and Linares-Pastén, Javier A.}},
  issn         = {{1756-4646}},
  keywords     = {{Novel bioactive peptides; Food plant peptides; Nutraceutical peptides; ndean food plants; Peptides production}},
  language     = {{eng}},
  month        = {{11}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Functional Foods}},
  title        = {{Bioactive peptides as functional food ingredients: Production, mechanisms of action, market trends, and future perspectives with emphasis on andean crops}},
  url          = {{http://dx.doi.org/10.1016/j.jff.2025.107109}},
  doi          = {{10.1016/j.jff.2025.107109}},
  volume       = {{135}},
  year         = {{2025}},
}