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An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

Wahlestedt, Martin LU ; Norddahl, Gudmundur LU ; Sten, Gerd LU ; Ugale, Amol LU ; Micha Frisk, Mary-Ann LU ; Mattsson, Ragnar LU ; Deierborg, Tomas LU ; Sigvardsson, Mikael LU and Bryder, David LU (2013) In Blood 121(21). p.4257-4264
Abstract
Key points Hematopoietic stem cell aging associate with stable transcriptional alterations that persist through transplantation.Somatic cell reprogramming of aged hematopoietic stem and progenitor cells reverses functional defects associated with hematopoietic aging.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Blood
volume
121
issue
21
pages
4257 - 4264
publisher
American Society of Hematology
external identifiers
  • wos:000321873900007
  • pmid:23476050
  • scopus:84880203894
ISSN
1528-0020
DOI
10.1182/blood-2012-11-469080
language
English
LU publication?
yes
id
cf2aa42c-3c16-41e2-bbf0-dc6b1681e891 (old id 3628314)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23476050?dopt=Abstract
date added to LUP
2013-04-04 15:39:30
date last changed
2019-06-11 01:10:22
@article{cf2aa42c-3c16-41e2-bbf0-dc6b1681e891,
  abstract     = {Key points Hematopoietic stem cell aging associate with stable transcriptional alterations that persist through transplantation.Somatic cell reprogramming of aged hematopoietic stem and progenitor cells reverses functional defects associated with hematopoietic aging.},
  author       = {Wahlestedt, Martin and Norddahl, Gudmundur and Sten, Gerd and Ugale, Amol and Micha Frisk, Mary-Ann and Mattsson, Ragnar and Deierborg, Tomas and Sigvardsson, Mikael and Bryder, David},
  issn         = {1528-0020},
  language     = {eng},
  number       = {21},
  pages        = {4257--4264},
  publisher    = {American Society of Hematology},
  series       = {Blood},
  title        = {An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.},
  url          = {http://dx.doi.org/10.1182/blood-2012-11-469080},
  volume       = {121},
  year         = {2013},
}