Plasma Phospholipid Long-Chain n-3 Polyunsaturated Fatty Acids and Body Weight Change
(2011) In Obesity Facts 4(4). p.312-318- Abstract
- Objective: We investigated the association between the proportion of long-chain n-3 polyunsaturated fatty acids (PUFA) in plasma phospholipids from blood samples drawn at enrollment and subsequent change in body weight. Sex, age, and BMI were considered as potential effect modifiers. Method: A total of 1,998 women and men participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) were followed for a median of 4.9 years. The associations between the proportion of plasma phospholipid long-chain n-3 PUFA and change in weight were investigated using mixed-effect linear regression. Results: The proportion of long-chain n-3 PUFA was not associated with change in weight. Among all participants, the 1-year weight... (More)
- Objective: We investigated the association between the proportion of long-chain n-3 polyunsaturated fatty acids (PUFA) in plasma phospholipids from blood samples drawn at enrollment and subsequent change in body weight. Sex, age, and BMI were considered as potential effect modifiers. Method: A total of 1,998 women and men participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) were followed for a median of 4.9 years. The associations between the proportion of plasma phospholipid long-chain n-3 PUFA and change in weight were investigated using mixed-effect linear regression. Results: The proportion of long-chain n-3 PUFA was not associated with change in weight. Among all participants, the 1-year weight change was -0.7 g per 1% point higher long-chain n-3 PUFA level (95% confidence interval: -20.7 to 19.3). The results when stratified by sex, age, or BMI groups were not systematically different. Conclusion: The results of this study suggest that the proportion of long-chain n-3 PUFA in plasma phospholipids is not associated with subsequent change in body weight within the range of exposure in the general population. (Less)
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https://lup.lub.lu.se/record/2186714
- author
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Body weight, Cohort study, n-3 fatty acids, Omega-3 fatty acids, Weight, change
- in
- Obesity Facts
- volume
- 4
- issue
- 4
- pages
- 312 - 318
- publisher
- Karger
- external identifiers
-
- wos:000294763300009
- scopus:80053027100
- pmid:21921655
- ISSN
- 1662-4033
- DOI
- 10.1159/000330710
- language
- English
- LU publication?
- yes
- id
- e6fc6fc6-8874-4ba0-b568-5857c4007c8c (old id 2186714)
- date added to LUP
- 2016-04-01 09:48:19
- date last changed
- 2025-04-04 14:57:50
@article{e6fc6fc6-8874-4ba0-b568-5857c4007c8c,
abstract = {{Objective: We investigated the association between the proportion of long-chain n-3 polyunsaturated fatty acids (PUFA) in plasma phospholipids from blood samples drawn at enrollment and subsequent change in body weight. Sex, age, and BMI were considered as potential effect modifiers. Method: A total of 1,998 women and men participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) were followed for a median of 4.9 years. The associations between the proportion of plasma phospholipid long-chain n-3 PUFA and change in weight were investigated using mixed-effect linear regression. Results: The proportion of long-chain n-3 PUFA was not associated with change in weight. Among all participants, the 1-year weight change was -0.7 g per 1% point higher long-chain n-3 PUFA level (95% confidence interval: -20.7 to 19.3). The results when stratified by sex, age, or BMI groups were not systematically different. Conclusion: The results of this study suggest that the proportion of long-chain n-3 PUFA in plasma phospholipids is not associated with subsequent change in body weight within the range of exposure in the general population.}},
author = {{Jakobsen, Marianne U. and Dethlefsen, Claus and Due, Karen M. and Slimani, Nadia and Chajes, Veronique and May, Anne M. and Sorensen, Thorkild I. A. and Halkjaer, Jytte and Tjonneland, Anne and Clavel-Chapelon, Francoise and Boutron-Ruault, Marie-Christine and Fagherazzi, Guy and Teucher, Birgit and Kaaks, Rudolf and Boeing, Heiner and Schuetze, Madlen and Trichopoulou, Antonia and Zylis, Dimosthenis and Makrygiannis, George and Palli, Domenico and Mattiello, Amalia and Tagliabue, Giovanna and van der A, Daphne L. and Bueno-de-Mesquita, H. B. and Rodriguez, Laudina and Travier, Noemie and Molina-Montes, Esther and Huerta, Jose M. and Barricarte, Aurelio and Amiano, Pilar and Manjer, Jonas and Wirfält, Elisabet and Johansson, Ingegerd and Hallmans, Goran and Khaw, Kay-Tee and Wareham, Nicholas J. and Crowe, Francesca and Romieu, Isabelle and Riboli, Elio and Peeters, Petra H. M. and Overvad, Kim}},
issn = {{1662-4033}},
keywords = {{Body weight; Cohort study; n-3 fatty acids; Omega-3 fatty acids; Weight; change}},
language = {{eng}},
number = {{4}},
pages = {{312--318}},
publisher = {{Karger}},
series = {{Obesity Facts}},
title = {{Plasma Phospholipid Long-Chain n-3 Polyunsaturated Fatty Acids and Body Weight Change}},
url = {{http://dx.doi.org/10.1159/000330710}},
doi = {{10.1159/000330710}},
volume = {{4}},
year = {{2011}},
}