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- 2017
-
Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space
Rudling, Axel ; Gustafsson, Robert ; Almlöf, Ingrid ; Homan, Evert ; Scobie, Martin ; Warpman Berglund, Ulrika ; Helleday, Thomas ; Stenmark, Pål LU
and Carlsson, Jens
(2017)
In Journal of Medicinal Chemistry
60(19).
p.8160-8169
Mark
- 2016
- Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis
- 2013
-
Effect of poly(propylene imine) glycodendrimers on β-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and Alzheimer's disease
Klementieva, O LU
; Aso, E
; Filippini, D
; Benseny-Cases, N
; Carmona, M
; Juvés, S
; Appelhans, D
; Cladera, J
and Ferrer, I
(2013)
In Biomacromolecules
14(10).
p.80-3570
Mark
- 2012
-
Oleic acid is a key cytotoxic component of HAMLET-like complexes
Permyakov, Sergei E ; Knyazeva, Ekaterina L ; Khasanova, Leysan M ; Fadeev, Roman S ; Zhadan, Andrei P ; Roche-Hakansson, Hazeline ; Håkansson, Anders P LU
; Akatov, Vladimir S
and Permyakov, Eugene A
(2012)
In Biological Chemistry
393(1-2).
p.85-92
Mark
- Discovery of benzothiazole guanidines as novel inhibitors of thrombin and trypsin IV
- Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors
- 2011
- Bacterial ferrochelatase turns human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase.
- Crystal structure of a copper-transporting PIB-type ATPase
- 2010
- Novel APC-cleavage sites in FVa providing insights into mechanisms of action of APC and its cofactor protein S.
- Discovery of a class of calcium sensing receptor positive allosteric modulators; 1-(benzothiazol-2-yl)-1-phenylethanols