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- 2019
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Mark
Pharmacologic exhaustion of suppressor cells with tasquinimod enhances bacterial clearance during tuberculosis
(
- Contribution to journal › Letter
- 2018
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Mark
Induction of S100A9 homodimer formation in vivo
(
- Contribution to journal › Article
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Mark
Paquinimod prevents development of diabetes in the non-obese diabetic (NOD) mouse
(
- Contribution to journal › Article
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Mark
Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation
(
- Contribution to journal › Article
- 2016
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Mark
The anti-tumor effect of the quinoline-3-carboxamide tasquinimod : Blockade of recruitment of CD11b+ Ly6Chi cells to tumor tissue reduces tumor growth
(
- Contribution to journal › Article
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Mark
CD14 is a co-receptor for TLR4 in the S100A9-induced pro-inflammatory response in monocytes
(
- Contribution to journal › Article
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Mark
Paquinimod reduces skin fibrosis in tight skin 1 mice, an experimental model of systemic sclerosis
(
- Contribution to journal › Article
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Mark
Platelet-derived S100A8/A9 and cardiovascular disease in systemic lupus erythematosus.
2016) In Arthritis & Rheumatology(
- Contribution to journal › Article
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Mark
IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition.
(
- Contribution to journal › Article
- 2015
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Mark
S100A9 as a pharmacological target molecule in inflammation and cancer.
(
- Contribution to journal › Article
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Mark
S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.
(
- Contribution to journal › Article
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Mark
Vesicular Location and Transport of S100A8 and S100A9 Proteins in Monocytoid Cells.
(
- Contribution to journal › Article
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Mark
Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment.
(
- Contribution to journal › Article
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Mark
Myeloid-related protein 14 promote inflammation and injury in meningitis.
(
- Contribution to journal › Article
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Mark
Tasquinimod Modulates Suppressive Myeloid Cells and Enhances Cancer Immunotherapies in Murine Models
(
- Contribution to journal › Article
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Mark
Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis.
(
- Contribution to journal › Article
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Mark
Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion.
(
- Contribution to journal › Article
- 2014
-
Mark
Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity.
(
- Contribution to journal › Article
-
Mark
The quinoline-3-carboxamide paquinimod (ABR-215757) reduces leukocyte recruitment during sterile inflammation: Leukocyte- and context-specific effects.
(
- Contribution to journal › Article
-
Mark
Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment.
(
- Contribution to journal › Article
-
Mark
High density of S100A9 positive inflammatory cells in prostate cancer stroma is associated with poor outcome.
(
- Contribution to journal › Article
- 2013
-
Mark
Human S100A9 Protein Is Stabilized by Inflammatory Stimuli via the Formation of Proteolytically-Resistant Homodimers.
(
- Contribution to journal › Article
-
Mark
Amelioration of Experimental Autoimmune Encephalomyelitis by the Quinoline-3-Carboxamide Paquinimod (ABR-215757): Reduced Priming of Proinflammatory Effector CD4(+) T Cells.
(
- Contribution to journal › Article
-
Mark
The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function.
(
- Contribution to journal › Article
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Mark
Common Interactions between S100A4 and S100A9 Defined by a Novel Chemical Probe.
(
- Contribution to journal › Article
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Mark
Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus.
(
- Contribution to journal › Article
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Mark
Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors.
(
- Contribution to journal › Article
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Mark
Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling within the Compromised Cancer Microenvironment
(
- Contribution to journal › Article
- 2012
-
Mark
S100A9 and tumor growth.
(
- Contribution to journal › Article
-
Mark
CD11b(+)Ly6C(++)Ly6G(-) cells show distinct function in mice with chronic inflammation or tumor burden
(
- Contribution to journal › Article
-
Mark
Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050)
(
- Contribution to journal › Article
-
Mark
Induction of NFκB responses by the S100A9 protein is TLR4-dependent.
(
- Contribution to journal › Article
-
Mark
S100A9 Interaction with TLR4 Promotes Tumor Growth.
(
- Contribution to journal › Article
-
Mark
Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: Studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in patients with systemic lupus erythematosus
(
- Contribution to journal › Article
- 2011
-
Mark
Specific effect of immunomodulatory quinoline-3-carboxamide ABR-215757 in GM-CSF stimulated bone marrow cell cultures: Block of initiation of proliferation of Gr-1(+) cells.
(
- Contribution to journal › Article
-
Mark
Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus
(
- Contribution to journal › Article
-
Mark
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia
(
- Contribution to journal › Article
- 2010
-
Mark
Indoleamine 2,3-dioxygenase (IDO) activity influence tumor growth in the TRAMP prostate cancer model.
(
- Contribution to journal › Article
-
Mark
Selective depletion of splenic CD4 dendritic cells in mice treated with immunomodulatory quinoline-3-carboxamide ABR-215757.
(
- Contribution to journal › Article
-
Mark
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
(
- Contribution to journal › Article
- 2009
-
Mark
Antioxidant metabolism induced by quinic acid. increased urinary excretion of tryptophan and nicotinamide.
(
- Contribution to journal › Article
-
Mark
Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.
(
- Contribution to journal › Article
-
Mark
From the fetal liver to spleen and gut: the highway to natural antibody
(
- Contribution to journal › Article
- 2008
-
Mark
A subset of dendritic cells express joining chain (J-chain) protein
(
- Contribution to journal › Article
-
Mark
Effect on interferon-inducible gene expression signature by ABR215757, a new drug in development for SLE
2008) 72nd Annual Scientific Meeting of the American-College-of-Rheumatology/43rd Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals In Arthritis and Rheumatism 58(9). p.567-568(
- Contribution to journal › Published meeting abstract
-
Mark
IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis
(
- Contribution to journal › Article
- 2007
-
Mark
Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria
(
- Contribution to journal › Article
- 2006
-
Mark
Joining-chain (J-chain) negative mice are B cell memory deficient.
(
- Contribution to journal › Article
-
Mark
The kappa promoter penta-decamer binding protein CBF-A interacts specifically with nucleophosmin in the nucleus only.
(
- Contribution to journal › Article
-
Mark
CArG box-binding factor-A interacts with multiple motifs in immunoglobulin promoters and has a regulated subcellular distribution.
(
- Contribution to journal › Article