The pathogenetic mechanisms behind MLL-rearranged acute leukemia in infancy

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2024
Mark Activating mutations remodel the chromatin accessibility landscape to drive distinct regulatory networks in KMT2A-rearranged acute leukemia
Zhang, Qirui ^LU ; Falqués-Costa, Ton ; Pilheden, Mattias ^LU ; Sturesson, Helena ^LU ; Ovlund, Tina ^LU ; Rissler, Vendela ^LU ; Castor, Anders ^LU ; Marquart, Hanne V.H. ; Lausen, Birgitte and Fioretos, Thoas ^LU , et al. (2024) In HemaSphere 8(9).
- Contribution to journal › Article
Mark SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia
Åbacka, Hannah ^LU ; Masoni, Samuele ^LU ; Poli, Giulio ; Huang, Peng ^LU ; Gusso, Francesco ; Granchi, Carlotta ; Minutolo, Filippo ; Tuccinardi, Tiziano ; Hagström-Andersson, Anna K. ^LU and Lindkvist-Petersson, Karin ^LU (2024) In Scientific Reports 14(1).
- Contribution to journal › Article
Mark CD4⁺CAR T-cell exhaustion associated with early relapse of multiple myeloma after BCMA CAR T-cell therapy
Ledergor, Guy ; Fan, Zenghua ; Wu, Kai ; McCarthy, Elizabeth ; Hyrenius-Wittsten, Axel ^LU ; Starzinski, Alec ; Chang, Hewitt ; Bridge, Mark ; Kwek, Serena and Cheung, Alexander , et al. (2024) In Blood Advances 8(13). p.3562-3575
- Contribution to journal › Article
Mark Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia
Malyukova, Alena ; Lahnalampi, Mari ; Falqués-Costa, Ton ^LU ; Pölönen, Petri ; Sipola, Mikko ; Mehtonen, Juha ; Teppo, Susanna ; Akopyan, Karen ; Viiliainen, Johanna and Lohi, Olli , et al. (2024) In Genome Biology 25(1).
- Contribution to journal › Article
Mark Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, Hanna ^LU ; Henningsson, Rasmus ^LU ; Puente-Moncada, Noelia ^LU ; Peña-Martínez, Pablo ^LU ; Sjöström, Ludvig ^LU ; Ågerstam, Helena ^LU ; Sandén, Carl ^LU ; Rissler, Marianne ^LU ; Castor, Anders ^LU and Marquart, Hanne , et al. (2024) In Blood 144(13). p.1399-1411
- Contribution to journal › Article
Mark Precision Diagnostics in Myeloid Malignancies : Development and Validation of a National Capture-Based Gene Panel
Orsmark-Pietras, Christina ^LU ; Lyander, Anna ; Ladenvall, Claes ^LU ; Hallström, Björn ^LU ; Staffas, Anna ; Awier, Hero ; Krstic, Aleksandra ; Baliakas, Panagiotis ; Barbany, Gisela and Håkansson, Cecilia Brunhoff , et al. (2024) In Genes Chromosomes and Cancer 63(7).
- Contribution to journal › Article
2023
Mark Genome-wide analysis of KMT2A-rearranged leukemia
Pilheden, Mattias ^LU (2023) In Lund University, Faculty of Medicine Doctoral Dissertation Series
- Thesis › Doctoral thesis (compilation)
Mark Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Rodriguez-Zabala, Maria ^LU ; Ramakrishnan, Ramprasad ^LU ; Reinbach, Katrin ^LU ; Ghosh, Somadri ^LU ; Oburoglu, Leal ^LU ; Falqués-Costa, Antoni ; Bellamkonda, Kishan ^LU ; Ehinger, Mats ^LU ; Peña-Martínez, Pablo ^LU and Puente-Moncada, Noelia ^LU , et al. (2023) In Blood Advances 7(18). p.5382-5395
- Contribution to journal › Article
2022
Mark Aquaglyceroporins and orthodox aquaporins in human adipocytes
Huang, Peng ^LU ; Hansen, Jesper S. ; Saba, Karim H. ^LU ; Bergman, Anna ^LU ; Negoita, Florentina ^LU ; Gourdon, Pontus ^LU ; Hagström-Andersson, Anna ^LU and Lindkvist-Petersson, Karin ^LU (2022) In Biochimica et Biophysica Acta - Biomembranes 1864(1).
- Contribution to journal › Article
Mark Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia
Pilheden, Mattias ^LU ; Ahlgren, Louise ^LU ; Hyrenius-Wittsten, Axel ^LU ; Gonzalez-Pena, Veronica ; Sturesson, Helena ^LU ; Hansen Marquart, Hanne Vibeke ; Lausen, Birgitte ; Castor, Anders ^LU ; Pronk, Cornelis Jan ^LU and Barbany, Gisela , et al. (2022) In HemaSphere 6(10). p.1-8
- Contribution to journal › Article

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The pathogenetic mechanisms behind MLL-rearranged acute leukemia in infancy

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