Isaac Canals

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2025
Mark Generation of iPSC Lines with Tagged α-Synuclein for Visualization of Endogenous Protein in Human Cellular Models of Neurodegenerative Disorders
Zetterdahl, Oskar G ^LU ; Crowe, James A ^LU ; Reyhani, Samira ^LU ; Güra, Miriam A ; Labastida-Botey, Ot ; Girard, Aline S ^LU ; Froese, D Sean ; Ahlenius, Henrik ^LU and Canals, Isaac ^LU (2025) In eNeuro 12(6).
- Contribution to journal › Article
Mark Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease
Matusova, Zuzana ; Dykstra, Werner ; de Pablo, Yolanda ; Zetterdahl, Oskar G. ^LU ; Canals, Isaac ^LU ; van Gelder, Charlotte A.G.H. ; Vos, Harmjan R. ; Pérez-Sala, Dolores ; Kubista, Mikael and Abaffy, Pavel , et al. (2025) In GLIA 73(1). p.57-79
- Contribution to journal › Article
2023
Mark Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
Canals, Isaac ^LU ; Comella-Bolla, Andrea ^LU ; Cepeda-Prado, Efrain ^LU ; Avaliani, Natalia ^LU ; Crowe, James A ^LU ; Oburoglu, Leal ^LU ; Bruzelius, Andreas ^LU ; King, Naomi ^LU ; Pajares, María A and Pérez-Sala, Dolores , et al. (2023) In Brain Communications 5(3). p.1-16
- Contribution to journal › Article
Mark Transcription Factor-Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo
Trovato, Francesco ^LU ; Stefani, Francesca Romana ^LU ; Li, Jiaxin ^LU ; Zetterdahl, Oskar G ^LU ; Canals, Isaac ^LU ; Ahlenius, Henrik ^LU and Bengzon, Johan ^LU (2023) In Molecular Cancer Therapeutics 22(2). p.274-286
- Contribution to journal › Article
2022
Mark Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence
Oburoglu, Leal ^LU ; Mansell, Els ^LU ; Canals, Isaac ^LU ; Sigurdsson, Valgardur ^LU ; Guibentif, Carolina ^LU ; Soneji, Shamit ^LU and Woods, Niels Bjarne ^LU (2022) In EMBO Reports 23(2).
- Contribution to journal › Article
Mark FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis
Monsalve, Anuntxi ; Canals, Isaac ^LU and Oburoglu, Leal ^LU (2022) In Frontiers in Cell and Developmental Biology 10.
- Contribution to journal › Article
Mark Genome Editing Using Cas9-gRNA Ribonucleoprotein in Human Pluripotent Stem Cells for Disease Modeling
Benetó, Noelia ; Grinberg, Daniel ; Vilageliu, Lluïsa and Canals, Isaac ^LU (2022) In Methods in Molecular Biology 2549. p.409-425
- Chapter in Book/Report/Conference proceeding › Book chapter
Mark Transcription factor-based direct conversion of human fibroblasts to functional astrocytes
Quist, Ella ^LU ; Trovato, Francesco ^LU ; Avaliani, Natalia ^LU ; Zetterdahl, Oskar G. ^LU ; Gonzalez-Ramos, Ana ^LU ; Hansen, Marita G. ^LU ; Kokaia, Merab ^LU ; Canals, Isaac ^LU and Ahlenius, Henrik ^LU (2022) In Stem Cell Reports 17(7). p.1620-1635
- Contribution to journal › Article
2021
Mark NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities
Tolomeo, Anna Maria ; Laterza, Cecilia ^LU ; Grespan, Eleonora ; Michielin, Federica ; Canals, Isaac ^LU ; Kokaia, Zaal ^LU ; Muraca, Maurizio ; Gagliano, Onelia and Elvassore, Nicola (2021) In Frontiers in Cellular Neuroscience 15.
- Contribution to journal › Article
Mark Transcription Factor-Based Strategies to Generate Neural Cell Types from Human Pluripotent Stem Cells
Canals, Isaac ^LU ; Quist, Ella ^LU and Ahlenius, Henrik ^LU (2021) In Cellular Reprogramming 23(4). p.206-220
- Contribution to journal › Scientific review

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