Efraim Westholm

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2024
Mark MicroRNA 29 modulates β-cell mitochondrial metabolism and insulin secretion via underlying miR-29-OXPHOS complex pathways
Cowan, E. ^LU ; Sun, J. ^LU ; Hamilton, A. ^LU ; Ruhrmann, S. ^LU ; Karagiannopoulos, A. ^LU ; Westholm, E. ^LU ; Ofori, J. K. ^LU ; Luan, C. ^LU ; Zhang, E. ^LU and Mulder, H. ^LU , et al. (2024) In Acta Physiologica 240(8).
- Contribution to journal › Article
Mark Regulation of insulin secretion by local and circulating factors - Investigations on islet proteins and microRNAs
Westholm, Efraim ^LU (2024) In Lund University, Faculty of Medicine Doctoral Dissertation Series
- Thesis › Doctoral thesis (compilation)
Mark IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
Westholm, Efraim ^LU ; Karagiannopoulos, Alexandros ^LU ; Kattner, Nicole ; Al-Selwi, Yara ; Merces, George ; Shaw, James AM ; Wendt, Anna ^LU and Eliasson, Lena ^LU (2024) In iScience 27(9).
- Contribution to journal › Article
2023
Mark Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells
Karagiannopoulos, Alexandros ^LU ; Westholm, Efraim ^LU ; Ofori, Jones K ^LU ; Cowan, Elaine ^LU ; Esguerra, Jonathan L S ^LU and Eliasson, Lena ^LU (2023) In iScience 26(5). p.1-23
- Contribution to journal › Article
Mark Interleukin-4 reduces insulin secretion in human islets from healthy but not type-2 diabetic donors
Westholm, Efraim ^LU ; Edlund, Anna ^LU ; Karagiannopoulos, Alexandros ^LU ; Wendt, Anna ^LU and Eliasson, Lena ^LU (2023) In Biochemical and Biophysical Research Communications 649. p.87-92
- Contribution to journal › Article
2022
Mark Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion
Ofori, Jones ^LU ; Karagiannopoulos, Alexandros ^LU ; Nagao, Mototsugu ^LU ; Westholm, Efraim ^LU ; Ramadan, Shaima ^LU ; Wendt, Anna ^LU ; Esguerra, Jonathan LS ^LU and Eliasson, Lena ^LU (2022) In Diabetes 71(2). p.275-284
- Contribution to journal › Article
2021
Mark Islet Function in the Pathogenesis of Cystic Fibrosis-Related Diabetes Mellitus
Westholm, Efraim ^LU ; Wendt, Anna ^LU and Eliasson, Lena ^LU (2021) In Clinical Medicine Insights: Endocrinology and Diabetes 14. p.1-7
- Contribution to journal › Scientific review
Mark MiR-205 is up-regulated in islets of diabetes-susceptible mice and targets the diabetes gene Tcf7l2
Ouni, Meriem ; Gottmann, Pascal ; Westholm, Efraim ^LU ; Schwerbel, Kristin ; Jähnert, Markus ; Stadion, Mandy ; Rittig, Kilian ; Vogel, Heike and Schürmann, Annette (2021) In Acta Physiologica 232(4).
- Contribution to journal › Article