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2024
A genomic mutational constraint map using variation in 76,156 human genomes Chen, S. ; Groop, L. ^LU ; Melander, O. ^LU ; Nilsson, P.M. ^LU ; Smith, J. Gustav ^LU ; MacArthur, D.G. and Karczewski, K.J. (2024) In Nature 625(7993). p.92-100
- Contribution to journal › Article
2023
Identification of biomarkers for glycaemic deterioration in type 2 diabetes Slieker, Roderick C ; Donnelly, Louise A ; Akalestou, Elina ; Lopez-Noriega, Livia ; Melhem, Rana ; Güneş, Ayşim ; Abou Azar, Frederic ; Efanov, Alexander ; Georgiadou, Eleni and Muniangi-Muhitu, Hermine , et al. (2023) In Nature Communications 14. p.1-18
- Contribution to journal › Article
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake Williamson, A. ; Hatem, G. ^LU ; Aly, D.M. ^LU ; Ahlqvist, E. ^LU ; Prasad, R.B. ^LU ; Groop, L. ^LU ; Meigs, J.B. and Langenberg, C. (2023) In Nature Genetics 55(6). p.973-983
- Contribution to journal › Article
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification Lagou, Vasiliki ; Ahlqvist, Emma ^LU ; Groop, Leif ^LU and Prokopenko, Inga (2023) In Nature Genetics 55(9). p.1448-1461
- Contribution to journal › Article
Genetic insights into resting heart rate and its role in cardiovascular disease van de Vegte, Y.J. ; Ladenvall, C. ^LU ; Melander, O. ^LU ; Groop, L. ^LU ; Smith, J.G. ^LU and van der Harst, P. (2023) In Nature Communications 14(1).
- Contribution to journal › Article
Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease Dwivedi, Om Prakash ; Barreiro, Karina ; Käräjämäki, Annemari ; Valo, Erkka ; Giri, Anil K. ; Prasad, Rashmi B. ^LU ; Roy, Rishi Das ; Thorn, Lena M. ; Rannikko, Antti and Holthöfer, Harry , et al. (2023) In iScience 26(5).
- Contribution to journal › Article
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits Brown, A.A. ; Giordano, G.N. ^LU ; Ridderstråle, M. ^LU ; Franks, P.W. ^LU ; Atabaki-Pasdar, N. ^LU ; Fitipaldi, H. ^LU ; Groop, L. ^LU ; Klintenberg, M. ^LU ; Pomares-Millan, H. ^LU and Viñuela, A. (2023) In Nature Communications 14.
- Contribution to journal › Article
Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models Allesøe, R.L. ; Ridderstråle, M. ^LU ; Giordano, G.N. ^LU ; Franks, P.W. ^LU ; Groop, L. ^LU ; Pasdar, N.A. ; Fitipaldi, H. ^LU ; Kurbasic, A. ^LU ; Mutie, P. ^LU and Pomares-Millan, H. ^LU , et al. (2023) In Nature Biotechnology
- Contribution to journal › Article
Smoking, use of smokeless tobacco, HLA genotypes and incidence of latent autoimmune diabetes in adults Edstorp, Jessica ; Wei, Yuxia ; Ahlqvist, Emma ^LU ; Alfredsson, Lars ; Grill, Valdemar ; Groop, Leif ^LU ; Rasouli, Bahareh ; Sørgjerd, Elin P. ; Thorsby, Per M. and Tuomi, Tiinamaija ^LU , et al. (2023) In Diabetologia 66. p.70-81
- Contribution to journal › Article
2022
Subgroups of patients with young-onset type 2 diabetes in India reveal insulin deficiency as a major driver Prasad, Rashmi B ^LU ; Asplund, Olof ^LU ; Shukla, Sharvari R ; Wagh, Rucha ; Kunte, Pooja ; Bhat, Dattatrey ; Parikh, Malay ; Shah, Meet ; Phatak, Sanat and Käräjämäki, Annemari , et al. (2022) In Diabetologia 65(1). p.65-78
- Contribution to journal › Article