Christopher Douse

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2025
Mark PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation
Madej, Magdalena ^LU ; Ngoc, Phuong Cao Thi ^LU ; Muthukumar, Sowndarya ^LU ; Konturek-Cieśla, Anna ; Tucciarone, Silvia ^LU ; Germanos, Alexandre ^LU ; Ashworth, Christian ^LU ; Kotarsky, Knut ^LU ; Ghosh, Sudip ^LU and Fan, Zhimeng ^LU , et al. (2025) In Cell Reports 44(6).
- Contribution to journal › Article
2024
Mark Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
Horváth, Vivien ^LU ; Garza, Raquel ^LU ; Jönsson, Marie E ^LU ; Johansson, Pia A ^LU ; Adami, Anita ^LU ; Christoforidou, Georgia ^LU ; Karlsson, Ofelia ^LU ; Castilla Vallmanya, Laura ^LU ; Koutounidou, Symela ^LU and Gerdes, Patricia ^LU , et al. (2024) In Nature Structural & Molecular Biology 31(10). p.1543-1556
- Contribution to journal › Article
Mark The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
Gustavsson, Emil K. ; Sethi, Siddharth ; Gao, Yujing ; Brenton, Jonathan W. ; García-Ruiz, Sonia ; Zhang, David ; Garza, Raquel ^LU ; Reynolds, Regina H. ; Evans, James R. and Chen, Zhongbo , et al. (2024) In Science Advances 10(26).
- Contribution to journal › Article
Mark Crystal structure and biochemical activity of the macrodomain from rubella virus p150
Stoll, Guido A ; Nikolopoulos, Nikos ; Zhai, Haoming ; Zhang, Liao ; Douse, Christopher H ^LU and Modis, Yorgo (2024) In Journal of Virology 98(2). p.1-17
- Contribution to journal › Article
Mark DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor
Pandiloski, Ninoslav ^LU ; Horváth, Vivien ^LU ; Karlsson, Ofelia ^LU ; Koutounidou, Symela ^LU ; Dorazehi, Fereshteh ^LU ; Christoforidou, Georgia ^LU ; Matas-Fuentes, Jon ; Gerdes, Patricia ^LU ; Garza, Raquel ^LU and Jönsson, Marie E ^LU , et al. (2024) In Nature Communications 15.
- Contribution to journal › Article
2023
Mark LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Garza, Raquel ^LU ; Atacho, Diahann A M ^LU ; Adami, Anita ^LU ; Gerdes, Patricia ^LU ; Vinod, Meghna ; Hsieh, PingHsun ; Karlsson, Ofelia ^LU ; Horvath, Vivien ^LU ; Johansson, Pia A ^LU and Pandiloski, Ninoslav ^LU , et al. (2023) In Science Advances 9(44).
- Contribution to journal › Article
Mark The DUF3715 domain has a conserved role in RNA-directed transposon silencing
Schöpp, Theresa ; Prigozhin, Daniil M ; Douse, Christopher ^LU ; Kaji, Keisuke ; Cook, Atlanta G and O'Carroll, Donal (2023) In RNA 29(10). p.1471-1480
- Contribution to journal › Article
2022
Mark A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
Johansson, Pia A ^LU ; Brattås, Per Ludvik ^LU ; Douse, Christopher H ^LU ; Hsieh, PingHsun ; Adami, Anita ^LU ; Pontis, Julien ; Grassi, Daniela ^LU ; Garza, Raquel ^LU ; Sozzi, Edoardo ^LU and Cataldo, Rodrigo ^LU , et al. (2022) In Cell Stem Cell 29(1). p.8-69
- Contribution to journal › Article
Mark Structure and functional mapping of the KRAB-KAP1 repressor complex
Stoll, Guido A ; Pandiloski, Ninoslav ^LU ; Douse, Christopher H ^LU and Modis, Yorgo (2022) In EMBO Journal 41(24).
- Contribution to journal › Article
2020
Mark TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
Douse, Christopher H. ^LU ; Tchasovnikarova, Iva A. ; Timms, Richard T. ; Protasio, Anna V. ; Seczynska, Marta ; Prigozhin, Daniil M. ; Albecka, Anna ; Wagstaff, Jane ; Williamson, James C. and Freund, Stefan M.V. , et al. (2020) In Nature Communications 11(1).
- Contribution to journal › Article

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