Hakon Leffler
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- 2022
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Mark
Site-specific N-glycan profiles of α5β1 integrin from rat liver
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- Contribution to journal › Article
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Mark
Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors
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- Contribution to journal › Article
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Mark
Engineering the Ligand Specificity of the Human Galectin-1 by Incorporation of Tryptophan Analogues
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- Contribution to journal › Article
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Mark
Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside
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- Contribution to journal › Article
- 2021
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Mark
Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain : Structure-based design and optimisation
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- Contribution to journal › Article
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Mark
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression
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- Contribution to journal › Article
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Mark
Synthesis and Biological Studies of O3-Aryl Galactosides as Galectin Inhibitors
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- Contribution to journal › Article
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Mark
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis
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- Contribution to journal › Article
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Mark
Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C
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- Contribution to journal › Article
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Mark
Chemokines modulate glycan binding and the immunoregulatory activity of galectins
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- Contribution to journal › Article
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Mark
Selective Galectin-8N Ligands : The Design and Synthesis of Phthalazinone-d-Galactals
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- Contribution to journal › Article
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Mark
Structure-Guided Design of d -Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain
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- Contribution to journal › Article
- 2020
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Mark
Epimers Switch Galectin-9 Domain Selectivity : 3 N-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal
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- Contribution to journal › Article
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Mark
In Vivo Veritas : 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors
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- Contribution to journal › Article
- 2019
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Mark
Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects
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- Contribution to journal › Article
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Mark
Extracellular and intracellular small-molecule galectin-3 inhibitors
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- Contribution to journal › Article
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Mark
Human trophoblast requires galectin-3 for cell migration and invasion
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- Contribution to journal › Article
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Mark
Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding
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- Contribution to journal › Article
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Mark
An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade
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- Contribution to journal › Article
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Mark
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
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- Contribution to journal › Article