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The Malmö Diet and Cancer Study: representativity, cancer incidence and mortality in participants and non-participants

Manjer, Jonas LU ; Carlsson, S; Elmståhl, Sölve LU ; Gullberg, Bo LU ; Janzon, Lars LU ; Lindstrom, M LU ; Mattisson, Iréne LU and Berglund, Göran LU (2001) In European Journal of Cancer Prevention 10(6). p.489-499
Abstract
In order to investigate potential selection bias in population-based cohort studies, participants (n = 28098) and non-participants (n = 40807) in the Malmo Diet and Cancer Study (MDCS) were compared with regard to cancer incidence and mortality. MDCS participants were also compared with participants in a mailed health survey with regard to subjective health, socio-demographic characteristics and lifestyle. Cancer incidence prior to recruitment was lower in non-participants, Cox proportional hazards analysis yielded a relative risk (RR) with a 95% confidence interval of 0.95 (0.90-1.00), compared with participants. During recruitment, cancer incidence was higher in non-participants, RR: 1.08 (1.01-1.17). Mortality was higher in... (More)
In order to investigate potential selection bias in population-based cohort studies, participants (n = 28098) and non-participants (n = 40807) in the Malmo Diet and Cancer Study (MDCS) were compared with regard to cancer incidence and mortality. MDCS participants were also compared with participants in a mailed health survey with regard to subjective health, socio-demographic characteristics and lifestyle. Cancer incidence prior to recruitment was lower in non-participants, Cox proportional hazards analysis yielded a relative risk (RR) with a 95% confidence interval of 0.95 (0.90-1.00), compared with participants. During recruitment, cancer incidence was higher in non-participants, RR: 1.08 (1.01-1.17). Mortality was higher in non-participants both during, 3.55 (3.13-4.03), and following the recruitment period, 2.21 (2.03-2.41). The proportion reporting good health was higher in the MDCS than in the mailed health survey (where 74.6% participated), but the socio-demographic structure was similar. We conclude that mortality is higher in non-participants than in participants during recruitment and follow-up. It is also suggested that non-participants may have a lower cancer incidence prior to recruitment but a higher incidence during the recruitment period. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
socio-demography, representativity, participants, non-participants, Cancer incidence, mortality
in
European Journal of Cancer Prevention
volume
10
issue
6
pages
489 - 499
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000173084100003
  • pmid:11916347
  • scopus:0035680020
ISSN
1473-5709
language
English
LU publication?
yes
id
5e12c85f-02b8-4711-95fa-2285c360c026 (old id 1119817)
date added to LUP
2008-07-04 14:21:09
date last changed
2018-08-19 03:25:22
@article{5e12c85f-02b8-4711-95fa-2285c360c026,
  abstract     = {In order to investigate potential selection bias in population-based cohort studies, participants (n = 28098) and non-participants (n = 40807) in the Malmo Diet and Cancer Study (MDCS) were compared with regard to cancer incidence and mortality. MDCS participants were also compared with participants in a mailed health survey with regard to subjective health, socio-demographic characteristics and lifestyle. Cancer incidence prior to recruitment was lower in non-participants, Cox proportional hazards analysis yielded a relative risk (RR) with a 95% confidence interval of 0.95 (0.90-1.00), compared with participants. During recruitment, cancer incidence was higher in non-participants, RR: 1.08 (1.01-1.17). Mortality was higher in non-participants both during, 3.55 (3.13-4.03), and following the recruitment period, 2.21 (2.03-2.41). The proportion reporting good health was higher in the MDCS than in the mailed health survey (where 74.6% participated), but the socio-demographic structure was similar. We conclude that mortality is higher in non-participants than in participants during recruitment and follow-up. It is also suggested that non-participants may have a lower cancer incidence prior to recruitment but a higher incidence during the recruitment period.},
  author       = {Manjer, Jonas and Carlsson, S and Elmståhl, Sölve and Gullberg, Bo and Janzon, Lars and Lindstrom, M and Mattisson, Iréne and Berglund, Göran},
  issn         = {1473-5709},
  keyword      = {socio-demography,representativity,participants,non-participants,Cancer incidence,mortality},
  language     = {eng},
  number       = {6},
  pages        = {489--499},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {European Journal of Cancer Prevention},
  title        = {The Malmö Diet and Cancer Study: representativity, cancer incidence and mortality in participants and non-participants},
  volume       = {10},
  year         = {2001},
}