Advanced

Dietary fibre intake and ischaemic heart disease mortality: the European Prospective Investigation into Cancer and Nutrition-Heart study

Crowe, F. L.; Key, T. J.; Appleby, P. N.; Overvad, K.; Schmidt, E. B.; Egeberg, R.; Tjonneland, A.; Kaaks, R.; Teucher, B. and Boeing, H., et al. (2012) In European Journal of Clinical Nutrition 66(8). p.950-956
Abstract
BACKGROUND/OBJECTIVES: Evidence from prospective studies is consistent in showing an inverse association between dietary fibre intake and risk of ischaemic heart disease (IHD), but whether dietary fibre from various food sources differ in their effect on IHD risk is less clear. The objective of this study was to assess the associations of total and food sources of dietary fibre with IHD mortality in the European Prospective Investigation into Cancer and Nutrition-Heart study. SUBJECTS/METHODS: Participants were 306 331 men and women from eight European countries. Dietary fibre intake was assessed using centre or country-specific diet questionnaires and calibrated using a 24-h diet recall. RESULTS: After an average follow-up of 11.5 years,... (More)
BACKGROUND/OBJECTIVES: Evidence from prospective studies is consistent in showing an inverse association between dietary fibre intake and risk of ischaemic heart disease (IHD), but whether dietary fibre from various food sources differ in their effect on IHD risk is less clear. The objective of this study was to assess the associations of total and food sources of dietary fibre with IHD mortality in the European Prospective Investigation into Cancer and Nutrition-Heart study. SUBJECTS/METHODS: Participants were 306 331 men and women from eight European countries. Dietary fibre intake was assessed using centre or country-specific diet questionnaires and calibrated using a 24-h diet recall. RESULTS: After an average follow-up of 11.5 years, there were 2381 IHD deaths among participants without cardiovascular disease at baseline. The calibrated intake of dietary fibre was inversely related with IHD mortality; each 10 g/day was associated with a 15% lower risk (relative risk (RR) 0.85; 95% confidence interval (CI): 0.73-0.99, P = 0.031). There was no difference in the associations of the individual food sources of dietary fibre with the risk of IHD mortality; RR for each 5 g/day higher cereal fibre intake was 0.91 (CI: 0.82-1.01), RR for each 2.5 g/day fruit fibre intake was 0.94 (CI: 0.88-1.01) and RR for each 2.5 g/day vegetable fibre intake was 0.90 (95% CI: 0.76-1.07). CONCLUSION: A higher consumption of dietary fibre is associated with a lower risk of fatal IHD with no clear difference in the association with IHD for fibre from cereals, fruits or vegetables. (Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
dietary fibre, ischaemic heart disease, prospective cohort studies
in
European Journal of Clinical Nutrition
volume
66
issue
8
pages
950 - 956
publisher
Nature Publishing Group
external identifiers
  • wos:000307236900012
  • scopus:84864854647
ISSN
1476-5640
DOI
10.1038/ejcn.2012.51
language
English
LU publication?
yes
id
20a6e26c-b590-49e6-8df2-786ea1ac9e83 (old id 3059579)
date added to LUP
2012-10-05 07:13:32
date last changed
2017-01-01 06:32:03
@article{20a6e26c-b590-49e6-8df2-786ea1ac9e83,
  abstract     = {BACKGROUND/OBJECTIVES: Evidence from prospective studies is consistent in showing an inverse association between dietary fibre intake and risk of ischaemic heart disease (IHD), but whether dietary fibre from various food sources differ in their effect on IHD risk is less clear. The objective of this study was to assess the associations of total and food sources of dietary fibre with IHD mortality in the European Prospective Investigation into Cancer and Nutrition-Heart study. SUBJECTS/METHODS: Participants were 306 331 men and women from eight European countries. Dietary fibre intake was assessed using centre or country-specific diet questionnaires and calibrated using a 24-h diet recall. RESULTS: After an average follow-up of 11.5 years, there were 2381 IHD deaths among participants without cardiovascular disease at baseline. The calibrated intake of dietary fibre was inversely related with IHD mortality; each 10 g/day was associated with a 15% lower risk (relative risk (RR) 0.85; 95% confidence interval (CI): 0.73-0.99, P = 0.031). There was no difference in the associations of the individual food sources of dietary fibre with the risk of IHD mortality; RR for each 5 g/day higher cereal fibre intake was 0.91 (CI: 0.82-1.01), RR for each 2.5 g/day fruit fibre intake was 0.94 (CI: 0.88-1.01) and RR for each 2.5 g/day vegetable fibre intake was 0.90 (95% CI: 0.76-1.07). CONCLUSION: A higher consumption of dietary fibre is associated with a lower risk of fatal IHD with no clear difference in the association with IHD for fibre from cereals, fruits or vegetables.},
  author       = {Crowe, F. L. and Key, T. J. and Appleby, P. N. and Overvad, K. and Schmidt, E. B. and Egeberg, R. and Tjonneland, A. and Kaaks, R. and Teucher, B. and Boeing, H. and Weikert, C. and Trichopoulou, A. and Ouranos, V. and Valanou, E. and Masala, G. and Sieri, S. and Panico, S. and Tumino, R. and Matullo, G. and Bueno-de-Mesquita, H. B. and Boer, J. M. A. and Beulens, J. W. J. and van der Schouw, Y. T. and Quiros, J. R. and Buckland, G. and Sanchez, M-J and Dorronsoro, M. and Huerta, J. M. and Moreno-Iribas, C. and Hedblad, Bo and Jansson, J. H. and Wennberg, P. and Khaw, K-T and Wareham, N. and Ferrari, P. and Illner, A-K and Chuang, S-C and Norat, T. and Danesh, J. and Riboli, E.},
  issn         = {1476-5640},
  keyword      = {dietary fibre,ischaemic heart disease,prospective cohort studies},
  language     = {eng},
  number       = {8},
  pages        = {950--956},
  publisher    = {Nature Publishing Group},
  series       = {European Journal of Clinical Nutrition},
  title        = {Dietary fibre intake and ischaemic heart disease mortality: the European Prospective Investigation into Cancer and Nutrition-Heart study},
  url          = {http://dx.doi.org/10.1038/ejcn.2012.51},
  volume       = {66},
  year         = {2012},
}