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Test-specific differences in verbal memory assessments used prior to surgery in temporal lobe epilepsy

Ljung, Hanna LU ; Strandberg, Maria Compagno LU ; Björkman-Burtscher, Isabella M LU ; Psouni, Elia LU and Källén, Kristina LU (2018) In Epilepsy and Behavior 87. p.18-24
Abstract

OBJECTIVE: To study the relationship between two commonly used verbal memory tests in presurgical evaluation for temporal lobe epilepsy (TLE) in Sweden, the Claeson-Dahl Test for verbal learning and retention (CDT) and the Swedish version of the Rey Auditory Verbal Learning Test (RAVLT).

METHODS: Fifty-nine patients with TLE (male: 41%, mean: age 41.7 ± 12.3 years; epilepsy onset at mean age: 18.3 ± 13.1 years) previously tested with the CDT, the RAVLT, and three nonverbal memory tests on the same occasion were included. We performed (1) a principal component analysis (PCA) on test performances in the CDT and the RAVLT as well as in nonverbal memory tests; (2) a Pearson's correlation analysis for memory components, biological age,... (More)

OBJECTIVE: To study the relationship between two commonly used verbal memory tests in presurgical evaluation for temporal lobe epilepsy (TLE) in Sweden, the Claeson-Dahl Test for verbal learning and retention (CDT) and the Swedish version of the Rey Auditory Verbal Learning Test (RAVLT).

METHODS: Fifty-nine patients with TLE (male: 41%, mean: age 41.7 ± 12.3 years; epilepsy onset at mean age: 18.3 ± 13.1 years) previously tested with the CDT, the RAVLT, and three nonverbal memory tests on the same occasion were included. We performed (1) a principal component analysis (PCA) on test performances in the CDT and the RAVLT as well as in nonverbal memory tests; (2) a Pearson's correlation analysis for memory components, biological age, education, age at epilepsy onset, and self-rating scores for depression and anxiety; and (3) an estimation of clinically significant verbal memory impairment in patients with left TLE and left-sided hippocampal sclerosis.

RESULTS: The PCAs showed coherence between the learning variables of the CDT and the RAVLT and divergence between the recall variables of the two tests. The RAVLT delayed recall variable was correlated to four out of five nonverbal memory measures. Both tests showed 70-80% clinically significant impairment of verbal memory in patients with left TLE, with or without hippocampal sclerosis, similar to other cohorts with resistant TLE.

CONCLUSIONS: The construct structure of the two verbal memory differs. It was shown that the RAVLT correlated with visuospatial memory, whereas the CDT did not. The study highlights that there are important nonoverlapping features regarding verbal recall of the two tests, indicating that these tests cannot fully replace one another.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Epilepsy and Behavior
volume
87
pages
7 pages
publisher
Elsevier
external identifiers
  • scopus:85052232280
  • pmid:30153652
ISSN
1525-5069
DOI
10.1016/j.yebeh.2018.08.011
project
Predictors of Verbal Memory Deficits from Temporal Lobe Surgery in Epilepsy. Improving patient selection by investigation of methods used for predicting verbal memory following surgery.
language
English
LU publication?
yes
id
3854511a-87be-4e77-b340-5f888bf8b8ea
date added to LUP
2018-08-31 14:43:25
date last changed
2021-09-15 02:14:28
@article{3854511a-87be-4e77-b340-5f888bf8b8ea,
  abstract     = {<p>OBJECTIVE: To study the relationship between two commonly used verbal memory tests in presurgical evaluation for temporal lobe epilepsy (TLE) in Sweden, the Claeson-Dahl Test for verbal learning and retention (CDT) and the Swedish version of the Rey Auditory Verbal Learning Test (RAVLT).</p><p>METHODS: Fifty-nine patients with TLE (male: 41%, mean: age 41.7 ± 12.3 years; epilepsy onset at mean age: 18.3 ± 13.1 years) previously tested with the CDT, the RAVLT, and three nonverbal memory tests on the same occasion were included. We performed (1) a principal component analysis (PCA) on test performances in the CDT and the RAVLT as well as in nonverbal memory tests; (2) a Pearson's correlation analysis for memory components, biological age, education, age at epilepsy onset, and self-rating scores for depression and anxiety; and (3) an estimation of clinically significant verbal memory impairment in patients with left TLE and left-sided hippocampal sclerosis.</p><p>RESULTS: The PCAs showed coherence between the learning variables of the CDT and the RAVLT and divergence between the recall variables of the two tests. The RAVLT delayed recall variable was correlated to four out of five nonverbal memory measures. Both tests showed 70-80% clinically significant impairment of verbal memory in patients with left TLE, with or without hippocampal sclerosis, similar to other cohorts with resistant TLE.</p><p>CONCLUSIONS: The construct structure of the two verbal memory differs. It was shown that the RAVLT correlated with visuospatial memory, whereas the CDT did not. The study highlights that there are important nonoverlapping features regarding verbal recall of the two tests, indicating that these tests cannot fully replace one another.</p>},
  author       = {Ljung, Hanna and Strandberg, Maria Compagno and Björkman-Burtscher, Isabella M and Psouni, Elia and Källén, Kristina},
  issn         = {1525-5069},
  language     = {eng},
  pages        = {18--24},
  publisher    = {Elsevier},
  series       = {Epilepsy and Behavior},
  title        = {Test-specific differences in verbal memory assessments used prior to surgery in temporal lobe epilepsy},
  url          = {http://dx.doi.org/10.1016/j.yebeh.2018.08.011},
  doi          = {10.1016/j.yebeh.2018.08.011},
  volume       = {87},
  year         = {2018},
}