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Effects of Soluble and Insoluble Fractions from Bilberries, Black Currants, and Raspberries on Short-Chain Fatty Acid Formation, Anthocyanin Excretion, and Cholesterol in Rats.

Jakobsdottir, Greta LU ; Nilsson, Ulf LU ; Blanco, Narda LU ; Sterner, Olov LU and Nyman, Margareta LU (2014) In Journal of Agricultural and Food Chemistry 62(19). p.4359-4368
Abstract
Dietary fiber and flavonoids, important components in berries, are suggested to improve metabolic health. This study investigates whether soluble and insoluble fractions isolated from bilberry, black currant, and raspberry affect the formation of short-chain fatty acids (SCFAs), uptake and excretion of flavonoids, and levels of cholesterol differently. Cecal SCFA pools were higher in rats fed the soluble than the insoluble fractions (525 vs 166 μmol, P < 0.001), whereas higher concentrations of butyric acid were found in the distal colon and serum of rats fed the insoluble fractions (5 vs 3 μmol/g and 58 vs 29 μmol/L, respectively, P < 0.001). The soluble bilberry fraction gave lower amounts of liver cholesterol (56 mg) than the... (More)
Dietary fiber and flavonoids, important components in berries, are suggested to improve metabolic health. This study investigates whether soluble and insoluble fractions isolated from bilberry, black currant, and raspberry affect the formation of short-chain fatty acids (SCFAs), uptake and excretion of flavonoids, and levels of cholesterol differently. Cecal SCFA pools were higher in rats fed the soluble than the insoluble fractions (525 vs 166 μmol, P < 0.001), whereas higher concentrations of butyric acid were found in the distal colon and serum of rats fed the insoluble fractions (5 vs 3 μmol/g and 58 vs 29 μmol/L, respectively, P < 0.001). The soluble bilberry fraction gave lower amounts of liver cholesterol (56 mg) than the other berry fractions (87 ± 5 mg), formed the highest amount of SCFAs (746 vs 266 ± 21 μmol), and contributed the highest intake of anthocyanins. Cyanidin-3-glucoside monoglucuronide was detected in the urine of all groups, whereas anthocyanins were found only in groups fed soluble black currant and raspberry. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Agricultural and Food Chemistry
volume
62
issue
19
pages
4359 - 4368
publisher
The American Chemical Society
external identifiers
  • pmid:24797830
  • wos:000336078600015
  • scopus:84900793800
ISSN
0021-8561
DOI
10.1021/jf5007566
language
English
LU publication?
yes
id
6bac2ade-f0f2-49cb-86c8-aa7bfe668b1c (old id 4455810)
date added to LUP
2014-06-18 14:56:29
date last changed
2017-03-19 03:15:27
@article{6bac2ade-f0f2-49cb-86c8-aa7bfe668b1c,
  abstract     = {Dietary fiber and flavonoids, important components in berries, are suggested to improve metabolic health. This study investigates whether soluble and insoluble fractions isolated from bilberry, black currant, and raspberry affect the formation of short-chain fatty acids (SCFAs), uptake and excretion of flavonoids, and levels of cholesterol differently. Cecal SCFA pools were higher in rats fed the soluble than the insoluble fractions (525 vs 166 μmol, P &lt; 0.001), whereas higher concentrations of butyric acid were found in the distal colon and serum of rats fed the insoluble fractions (5 vs 3 μmol/g and 58 vs 29 μmol/L, respectively, P &lt; 0.001). The soluble bilberry fraction gave lower amounts of liver cholesterol (56 mg) than the other berry fractions (87 ± 5 mg), formed the highest amount of SCFAs (746 vs 266 ± 21 μmol), and contributed the highest intake of anthocyanins. Cyanidin-3-glucoside monoglucuronide was detected in the urine of all groups, whereas anthocyanins were found only in groups fed soluble black currant and raspberry.},
  author       = {Jakobsdottir, Greta and Nilsson, Ulf and Blanco, Narda and Sterner, Olov and Nyman, Margareta},
  issn         = {0021-8561},
  language     = {eng},
  number       = {19},
  pages        = {4359--4368},
  publisher    = {The American Chemical Society},
  series       = {Journal of Agricultural and Food Chemistry},
  title        = {Effects of Soluble and Insoluble Fractions from Bilberries, Black Currants, and Raspberries on Short-Chain Fatty Acid Formation, Anthocyanin Excretion, and Cholesterol in Rats.},
  url          = {http://dx.doi.org/10.1021/jf5007566},
  volume       = {62},
  year         = {2014},
}