Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.
(2015) In Genome Medicine 7(1).- Abstract
- Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain understanding of the processes underlying epigenetic and phenotypic characteristics of tumors.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5257627
- author
- Aine, Mattias LU ; Sjödahl, Gottfrid LU ; Eriksson, Pontus LU ; Veerla, Srinivas LU ; Lindgren, David LU ; Ringnér, Markus LU and Höglund, Mattias LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Genome Medicine
- volume
- 7
- issue
- 1
- article number
- 23
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:25810763
- wos:000351500200001
- scopus:84925342343
- pmid:25810763
- ISSN
- 1756-994X
- DOI
- 10.1186/s13073-015-0144-4
- language
- English
- LU publication?
- yes
- id
- 2c187d43-9a0f-40fb-aaef-ea1a2fa310d1 (old id 5257627)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25810763?dopt=Abstract
- date added to LUP
- 2016-04-01 12:53:22
- date last changed
- 2024-01-24 02:08:58
@article{2c187d43-9a0f-40fb-aaef-ea1a2fa310d1, abstract = {{Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain understanding of the processes underlying epigenetic and phenotypic characteristics of tumors.}}, author = {{Aine, Mattias and Sjödahl, Gottfrid and Eriksson, Pontus and Veerla, Srinivas and Lindgren, David and Ringnér, Markus and Höglund, Mattias}}, issn = {{1756-994X}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{Genome Medicine}}, title = {{Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.}}, url = {{https://lup.lub.lu.se/search/files/3030227/8228764}}, doi = {{10.1186/s13073-015-0144-4}}, volume = {{7}}, year = {{2015}}, }