Advanced

Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.

Aine, Mattias LU ; Sjödahl, Gottfrid LU ; Eriksson, Pontus LU ; Veerla, Srinivas LU ; Lindgren, David LU ; Ringnér, Markus LU and Höglund, Mattias LU (2015) In Genome Medicine 7(1).
Abstract
Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain understanding of the processes underlying epigenetic and phenotypic characteristics of tumors.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Genome Medicine
volume
7
issue
1
publisher
BioMed Central
external identifiers
  • pmid:25810763
  • wos:000351500200001
  • scopus:84925342343
ISSN
1756-994X
DOI
10.1186/s13073-015-0144-4
language
English
LU publication?
yes
id
2c187d43-9a0f-40fb-aaef-ea1a2fa310d1 (old id 5257627)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25810763?dopt=Abstract
date added to LUP
2015-04-04 17:35:41
date last changed
2017-11-19 03:41:12
@article{2c187d43-9a0f-40fb-aaef-ea1a2fa310d1,
  abstract     = {Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain understanding of the processes underlying epigenetic and phenotypic characteristics of tumors.},
  articleno    = {23},
  author       = {Aine, Mattias and Sjödahl, Gottfrid and Eriksson, Pontus and Veerla, Srinivas and Lindgren, David and Ringnér, Markus and Höglund, Mattias},
  issn         = {1756-994X},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Genome Medicine},
  title        = {Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.},
  url          = {http://dx.doi.org/10.1186/s13073-015-0144-4},
  volume       = {7},
  year         = {2015},
}