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Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia : A comparison between intermediate- and high-dose prophylaxis

Versloot, Olav; Berntorp, Erik LU ; Petrini, Pia; Ljung, Rolf LU ; Astermark, Jan LU ; Holmström, Margareta; de Kleijn, Piet and Fischer, Kathelijn (2019) In Haemophilia 25(2). p.244-251
Abstract

INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.

AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.

METHODS: Self-reported sports participation (type and frequency per week), physical functioning (SF-36PF : 100-0), joint status (HJHS: 0-144), perceived limitations (HALsum : 100-0) and physical activity (IPAQ) were recorded. Sports were classified according to National Haemophilia Foundation classification (5 categories, highest two were classified as high-risk sports). Sports... (More)

INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.

AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.

METHODS: Self-reported sports participation (type and frequency per week), physical functioning (SF-36PF : 100-0), joint status (HJHS: 0-144), perceived limitations (HALsum : 100-0) and physical activity (IPAQ) were recorded. Sports were classified according to National Haemophilia Foundation classification (5 categories, highest two were classified as high-risk sports). Sports participation and clinical outcome were compared according to country and age (18-22, 23-29, 30-40 years) using non-parametric tests and Spearman correlations (rho).

RESULTS: Seventy-one adult PWH (NL: 43, SWE: 28) completed sports questionnaires (mean age: 26 years). All participants engaged in sports, including 59.2% in high-risk sports (33.9% twice weekly). Dutch PWH showed a significant age-related decline in (high-risk) sports participation (7x/wk in PWH 18-22 years to 2x/wk in PWH 30-40 years, P < 0.05), joint health (HJHS: median 2-15.5, P < 0.01) and physical functioning (SF-36PF : median 100 to 77.5, P < 0.01), while Swedish did not. Sports participation was not associated with bleeding (Spearman's rho = -0.119).

CONCLUSION: All participants reported sports participation, including 59.2% in high-risk sports. Dutch PWH treated with intermediate-dose prophylaxis showed an age-related decline in sports participation, joint status and physical functioning, whereas Swedish PWH on high-dose prophylaxis did not. Sports participation was not associated with bleeding.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Haemophilia
volume
25
issue
2
pages
244 - 251
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • scopus:85063256472
ISSN
1351-8216
DOI
10.1111/hae.13683
language
English
LU publication?
yes
id
6a6b1cc5-1e38-4be9-b8b8-bd49d209cce9
date added to LUP
2019-02-04 10:39:41
date last changed
2019-04-23 04:45:31
@article{6a6b1cc5-1e38-4be9-b8b8-bd49d209cce9,
  abstract     = {<p>INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.</p><p>AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.</p><p>METHODS: Self-reported sports participation (type and frequency per week), physical functioning (SF-36PF : 100-0), joint status (HJHS: 0-144), perceived limitations (HALsum : 100-0) and physical activity (IPAQ) were recorded. Sports were classified according to National Haemophilia Foundation classification (5 categories, highest two were classified as high-risk sports). Sports participation and clinical outcome were compared according to country and age (18-22, 23-29, 30-40 years) using non-parametric tests and Spearman correlations (rho).</p><p>RESULTS: Seventy-one adult PWH (NL: 43, SWE: 28) completed sports questionnaires (mean age: 26 years). All participants engaged in sports, including 59.2% in high-risk sports (33.9% twice weekly). Dutch PWH showed a significant age-related decline in (high-risk) sports participation (7x/wk in PWH 18-22 years to 2x/wk in PWH 30-40 years, P &lt; 0.05), joint health (HJHS: median 2-15.5, P &lt; 0.01) and physical functioning (SF-36PF : median 100 to 77.5, P &lt; 0.01), while Swedish did not. Sports participation was not associated with bleeding (Spearman's rho = -0.119).</p><p>CONCLUSION: All participants reported sports participation, including 59.2% in high-risk sports. Dutch PWH treated with intermediate-dose prophylaxis showed an age-related decline in sports participation, joint status and physical functioning, whereas Swedish PWH on high-dose prophylaxis did not. Sports participation was not associated with bleeding.</p>},
  author       = {Versloot, Olav and Berntorp, Erik and Petrini, Pia and Ljung, Rolf and Astermark, Jan and Holmström, Margareta and de Kleijn, Piet and Fischer, Kathelijn},
  issn         = {1351-8216},
  language     = {eng},
  month        = {01},
  number       = {2},
  pages        = {244--251},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Haemophilia},
  title        = {Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia : A comparison between intermediate- and high-dose prophylaxis},
  url          = {http://dx.doi.org/10.1111/hae.13683},
  volume       = {25},
  year         = {2019},
}