Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia : A comparison between intermediate- and high-dose prophylaxis
Versloot, Olav ; Berntorp, Erik LU ; Petrini, Pia ; Ljung, Rolf LU
; Astermark, Jan
LU
; Holmström, Margareta
; de Kleijn, Piet
and Fischer, Kathelijn
(2019)
In Haemophilia
25(2).
p.244-251
- Abstract
INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.
AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.
METHODS: Self-reported sports participation (type and frequency per week), physical functioning (SF-36PF : 100-0), joint status (HJHS: 0-144), perceived limitations (HALsum : 100-0) and physical activity (IPAQ) were recorded. Sports were classified according to National Haemophilia Foundation classification (5 categories, highest two were classified as high-risk sports). Sports... (More)
INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.
AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.
METHODS: Self-reported sports participation (type and frequency per week), physical functioning (SF-36PF : 100-0), joint status (HJHS: 0-144), perceived limitations (HALsum : 100-0) and physical activity (IPAQ) were recorded. Sports were classified according to National Haemophilia Foundation classification (5 categories, highest two were classified as high-risk sports). Sports participation and clinical outcome were compared according to country and age (18-22, 23-29, 30-40 years) using non-parametric tests and Spearman correlations (rho).
RESULTS: Seventy-one adult PWH (NL: 43, SWE: 28) completed sports questionnaires (mean age: 26 years). All participants engaged in sports, including 59.2% in high-risk sports (33.9% twice weekly). Dutch PWH showed a significant age-related decline in (high-risk) sports participation (7x/wk in PWH 18-22 years to 2x/wk in PWH 30-40 years, P < 0.05), joint health (HJHS: median 2-15.5, P < 0.01) and physical functioning (SF-36PF : median 100 to 77.5, P < 0.01), while Swedish did not. Sports participation was not associated with bleeding (Spearman's rho = -0.119).
CONCLUSION: All participants reported sports participation, including 59.2% in high-risk sports. Dutch PWH treated with intermediate-dose prophylaxis showed an age-related decline in sports participation, joint status and physical functioning, whereas Swedish PWH on high-dose prophylaxis did not. Sports participation was not associated with bleeding.
(Less)
- author
- Versloot, Olav
; Berntorp, Erik
LU
; Petrini, Pia
; Ljung, Rolf
LU
; Astermark, Jan
LU
; Holmström, Margareta
; de Kleijn, Piet
and Fischer, Kathelijn
- organization
- publishing date
- 2019-01-28
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Haemophilia
- volume
- 25
- issue
- 2
- pages
- 244 - 251
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85063256472
- pmid:30690833
- ISSN
- 1351-8216
- DOI
- 10.1111/hae.13683
- language
- English
- LU publication?
- yes
- id
- 6a6b1cc5-1e38-4be9-b8b8-bd49d209cce9
- date added to LUP
- 2019-02-04 10:39:41
- date last changed
- 2024-06-25 06:03:00
@article{6a6b1cc5-1e38-4be9-b8b8-bd49d209cce9,
abstract = {{<p>INTRODUCTION: Differences in treatment and outcome have been reported for persons with haemophilia (PWH) on intermediate-dose (Dutch) and high-dose (Swedish) prophylaxis, but the potential influence of sports participation has not been considered.</p><p>AIM: To compare sports participation and clinical outcome between adult Dutch and Swedish PWH.</p><p>METHODS: Self-reported sports participation (type and frequency per week), physical functioning (SF-36PF : 100-0), joint status (HJHS: 0-144), perceived limitations (HALsum : 100-0) and physical activity (IPAQ) were recorded. Sports were classified according to National Haemophilia Foundation classification (5 categories, highest two were classified as high-risk sports). Sports participation and clinical outcome were compared according to country and age (18-22, 23-29, 30-40 years) using non-parametric tests and Spearman correlations (rho).</p><p>RESULTS: Seventy-one adult PWH (NL: 43, SWE: 28) completed sports questionnaires (mean age: 26 years). All participants engaged in sports, including 59.2% in high-risk sports (33.9% twice weekly). Dutch PWH showed a significant age-related decline in (high-risk) sports participation (7x/wk in PWH 18-22 years to 2x/wk in PWH 30-40 years, P < 0.05), joint health (HJHS: median 2-15.5, P < 0.01) and physical functioning (SF-36PF : median 100 to 77.5, P < 0.01), while Swedish did not. Sports participation was not associated with bleeding (Spearman's rho = -0.119).</p><p>CONCLUSION: All participants reported sports participation, including 59.2% in high-risk sports. Dutch PWH treated with intermediate-dose prophylaxis showed an age-related decline in sports participation, joint status and physical functioning, whereas Swedish PWH on high-dose prophylaxis did not. Sports participation was not associated with bleeding.</p>}},
author = {{Versloot, Olav and Berntorp, Erik and Petrini, Pia and Ljung, Rolf and Astermark, Jan and Holmström, Margareta and de Kleijn, Piet and Fischer, Kathelijn}},
issn = {{1351-8216}},
language = {{eng}},
month = {{01}},
number = {{2}},
pages = {{244--251}},
publisher = {{Wiley-Blackwell}},
series = {{Haemophilia}},
title = {{Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia : A comparison between intermediate- and high-dose prophylaxis}},
url = {{http://dx.doi.org/10.1111/hae.13683}},
doi = {{10.1111/hae.13683}},
volume = {{25}},
year = {{2019}},
}