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A single exercise session improves side-effects of chemotherapy in women with breast cancer : an observational study

Johnsson, Anna LU ; Demmelmaier, Ingrid ; Sjövall, Katarina LU ; Wagner, Philippe LU ; Olsson, Håkan LU and Tornberg, Åsa B LU (2019) In BMC Cancer 19. p.1-9
Abstract

BACKGROUND: To measure changes in four common chemotherapy related side-effects (low energy, stress, nausea and pain) immediately after a single exercise session within the first week after treatment.

METHODS: Thirty-eight patients with chemotherapy-treated breast cancer, participating in a multi-centre randomised controlled study, the Physical Training and Cancer study (Phys-Can) were included in this sub-study. The Phys-Can intervention included endurance and resistance training. Before and after a single training session (endurance or resistance) within the first week of chemotherapy, energy and stress were measured with the Stress-Energy Questionnaire during Leisure Time, and nausea and pain were assessed using a Visual Analog... (More)

BACKGROUND: To measure changes in four common chemotherapy related side-effects (low energy, stress, nausea and pain) immediately after a single exercise session within the first week after treatment.

METHODS: Thirty-eight patients with chemotherapy-treated breast cancer, participating in a multi-centre randomised controlled study, the Physical Training and Cancer study (Phys-Can) were included in this sub-study. The Phys-Can intervention included endurance and resistance training. Before and after a single training session (endurance or resistance) within the first week of chemotherapy, energy and stress were measured with the Stress-Energy Questionnaire during Leisure Time, and nausea and pain were assessed using a Visual Analog Scale 0-10. Paired t-tests were performed to analyse the changes, and linear regression was used to analyse associations with potential predictors.

RESULTS: Thirty-eight participants performed 26 endurance training sessions and 31 resistance training sessions in the first week after chemotherapy. Energy and nausea improved significantly after endurance training, and energy, stress and nausea improved significantly after resistance training. Energy increased (p = 0.03 and 0.001) and nausea decreased (p = 0.006 and 0.034) immediately after a single session of endurance or resistance training, and stress decreased (p = 0.014) after resistance exercise.

CONCLUSIONS: Both endurance and resistance training were followed by an immediate improvement of common chemotherapy-related side-effects in patients with breast cancer. Patients should be encouraged to exercise even if they suffer from fatigue or nausea during chemotherapy.

TRIAL REGISTRATION: NCT02473003, June 16, 2015.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Cancer
volume
19
article number
1073
pages
1 - 9
publisher
BioMed Central
external identifiers
  • pmid:31703567
  • scopus:85074714962
ISSN
1471-2407
DOI
10.1186/s12885-019-6310-0
language
English
LU publication?
yes
id
7387c03c-aad4-4bcc-9ede-879e05a5cf3d
date added to LUP
2019-11-14 13:33:13
date last changed
2020-02-14 03:00:02
@article{7387c03c-aad4-4bcc-9ede-879e05a5cf3d,
  abstract     = {<p>BACKGROUND: To measure changes in four common chemotherapy related side-effects (low energy, stress, nausea and pain) immediately after a single exercise session within the first week after treatment.</p><p>METHODS: Thirty-eight patients with chemotherapy-treated breast cancer, participating in a multi-centre randomised controlled study, the Physical Training and Cancer study (Phys-Can) were included in this sub-study. The Phys-Can intervention included endurance and resistance training. Before and after a single training session (endurance or resistance) within the first week of chemotherapy, energy and stress were measured with the Stress-Energy Questionnaire during Leisure Time, and nausea and pain were assessed using a Visual Analog Scale 0-10. Paired t-tests were performed to analyse the changes, and linear regression was used to analyse associations with potential predictors.</p><p>RESULTS: Thirty-eight participants performed 26 endurance training sessions and 31 resistance training sessions in the first week after chemotherapy. Energy and nausea improved significantly after endurance training, and energy, stress and nausea improved significantly after resistance training. Energy increased (p = 0.03 and 0.001) and nausea decreased (p = 0.006 and 0.034) immediately after a single session of endurance or resistance training, and stress decreased (p = 0.014) after resistance exercise.</p><p>CONCLUSIONS: Both endurance and resistance training were followed by an immediate improvement of common chemotherapy-related side-effects in patients with breast cancer. Patients should be encouraged to exercise even if they suffer from fatigue or nausea during chemotherapy.</p><p>TRIAL REGISTRATION: NCT02473003, June 16, 2015.</p>},
  author       = {Johnsson, Anna and Demmelmaier, Ingrid and Sjövall, Katarina and Wagner, Philippe and Olsson, Håkan and Tornberg, Åsa B},
  issn         = {1471-2407},
  language     = {eng},
  month        = {11},
  pages        = {1--9},
  publisher    = {BioMed Central},
  series       = {BMC Cancer},
  title        = {A single exercise session improves side-effects of chemotherapy in women with breast cancer : an observational study},
  url          = {http://dx.doi.org/10.1186/s12885-019-6310-0},
  doi          = {10.1186/s12885-019-6310-0},
  volume       = {19},
  year         = {2019},
}