Occupational sedentariness and breast cancer risk
Johnsson, Anna LU ; Broberg, Per LU ; Johnsson, Anders LU ; Tornberg, Åsa B. LU
and Olsson, Håkan
LU
(2017)
In Acta Oncologica
56(1).
p.75-80
- Abstract
Background: Epidemiological studies have indicated that physical activity reduces the risk of developing breast cancer. More recently, sedentary behavior has been suggested as a risk factor independent of physical activity level. The purpose of the present study was to investigate occupational sedentariness and breast cancer risk in pre- and postmenopausal women. Materials and methods: In a population-based prospective cohort study (n = 29 524), working history was assessed by a questionnaire between 1990 and 1992. Participants were classified as having: (1) sedentary occupations only; (2) mixed occupations or (3) non-sedentary occupations only. The association between occupational sedentariness and breast cancer incidence was analyzed... (More)
Background: Epidemiological studies have indicated that physical activity reduces the risk of developing breast cancer. More recently, sedentary behavior has been suggested as a risk factor independent of physical activity level. The purpose of the present study was to investigate occupational sedentariness and breast cancer risk in pre- and postmenopausal women. Materials and methods: In a population-based prospective cohort study (n = 29 524), working history was assessed by a questionnaire between 1990 and 1992. Participants were classified as having: (1) sedentary occupations only; (2) mixed occupations or (3) non-sedentary occupations only. The association between occupational sedentariness and breast cancer incidence was analyzed by Cox regression, adjusted for known risk factors and participation in competitive sports. Results: Women with a working history of occupational sedentariness had a significantly increased risk of breast cancer (adjusted HR 1.20; 95% CI 1.05, 1.37) compared with those with mixed or non-sedentary occupations. The association was stronger among women younger than 55 years (adjusted HR 1.54; 95% CI 1.20, 1.96), whereas no association was seen in women 55 years or older. Adjustment for participation in competitive sports did not change the association. Conclusions: We found that occupational sedentariness was associated with increased breast cancer risk, especially in women younger than 55 years. This may be a modifiable risk factor by planning breaks during the working day. Whether this reduces the risk of breast cancer needs to be further studied.
(Less)
- author
- Johnsson, Anna
LU
; Broberg, Per
LU
; Johnsson, Anders
LU
; Tornberg, Åsa B.
LU
and Olsson, Håkan
LU
- organization
- publishing date
- 2017
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Oncologica
- volume
- 56
- issue
- 1
- pages
- 6 pages
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:85001950460
- pmid:27919198
- wos:000392819600012
- ISSN
- 0284-186X
- DOI
- 10.1080/0284186X.2016.1262547
- project
- Fysisk aktivitet och stillasittande vid bröstcancer - Inverkan på incidens, välmående och prognos
- language
- English
- LU publication?
- yes
- id
- 7919c2c2-aa12-4da9-b5fb-39132bb59fe0
- date added to LUP
- 2016-12-28 08:30:58
- date last changed
- 2025-01-12 18:29:27
@article{7919c2c2-aa12-4da9-b5fb-39132bb59fe0,
abstract = {{<p>Background: Epidemiological studies have indicated that physical activity reduces the risk of developing breast cancer. More recently, sedentary behavior has been suggested as a risk factor independent of physical activity level. The purpose of the present study was to investigate occupational sedentariness and breast cancer risk in pre- and postmenopausal women. Materials and methods: In a population-based prospective cohort study (n = 29 524), working history was assessed by a questionnaire between 1990 and 1992. Participants were classified as having: (1) sedentary occupations only; (2) mixed occupations or (3) non-sedentary occupations only. The association between occupational sedentariness and breast cancer incidence was analyzed by Cox regression, adjusted for known risk factors and participation in competitive sports. Results: Women with a working history of occupational sedentariness had a significantly increased risk of breast cancer (adjusted HR 1.20; 95% CI 1.05, 1.37) compared with those with mixed or non-sedentary occupations. The association was stronger among women younger than 55 years (adjusted HR 1.54; 95% CI 1.20, 1.96), whereas no association was seen in women 55 years or older. Adjustment for participation in competitive sports did not change the association. Conclusions: We found that occupational sedentariness was associated with increased breast cancer risk, especially in women younger than 55 years. This may be a modifiable risk factor by planning breaks during the working day. Whether this reduces the risk of breast cancer needs to be further studied.</p>}},
author = {{Johnsson, Anna and Broberg, Per and Johnsson, Anders and Tornberg, Åsa B. and Olsson, Håkan}},
issn = {{0284-186X}},
language = {{eng}},
number = {{1}},
pages = {{75--80}},
publisher = {{Taylor & Francis}},
series = {{Acta Oncologica}},
title = {{Occupational sedentariness and breast cancer risk}},
url = {{http://dx.doi.org/10.1080/0284186X.2016.1262547}},
doi = {{10.1080/0284186X.2016.1262547}},
volume = {{56}},
year = {{2017}},
}