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CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?

Wuttge, Dirk LU ; Andreasson, A; Tufvesson, Ellen LU ; Johansson, Å; Scheja, Agneta LU ; Hellmark, Thomas LU ; Hesselstrand, Roger LU and Truedsson, Lennart LU (2016) In Scandinavian Journal of Rheumatology 45(2). p.107-113
Abstract
In systemic sclerosis (SSc)-related interstitial lung disease (ILD), elevated eosinophil counts in bronchoalveolar lavage are associated with a worse outcome. We hypothesized that eosinophils may be activated in the peripheral circulation, thereby increasing their recruitment to affected tissues and contributing to inflammation and fibrosis. The aim of this study was to characterize the blood eosinophils in SSc patients.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Rheumatology
volume
45
issue
2
pages
107 - 113
publisher
Taylor & Francis
external identifiers
  • pmid:26926492
  • scopus:84960399055
  • wos:000371919200004
ISSN
1502-7732
DOI
10.3109/03009742.2015.1054877
language
English
LU publication?
yes
id
6714435c-57ca-43dd-a5e9-8f6830f38547 (old id 8857116)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26926492?dopt=Abstract
date added to LUP
2016-03-15 09:40:54
date last changed
2017-07-23 03:12:13
@article{6714435c-57ca-43dd-a5e9-8f6830f38547,
  abstract     = {In systemic sclerosis (SSc)-related interstitial lung disease (ILD), elevated eosinophil counts in bronchoalveolar lavage are associated with a worse outcome. We hypothesized that eosinophils may be activated in the peripheral circulation, thereby increasing their recruitment to affected tissues and contributing to inflammation and fibrosis. The aim of this study was to characterize the blood eosinophils in SSc patients.},
  author       = {Wuttge, Dirk and Andreasson, A and Tufvesson, Ellen and Johansson, Å and Scheja, Agneta and Hellmark, Thomas and Hesselstrand, Roger and Truedsson, Lennart},
  issn         = {1502-7732},
  language     = {eng},
  number       = {2},
  pages        = {107--113},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Rheumatology},
  title        = {CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?},
  url          = {http://dx.doi.org/10.3109/03009742.2015.1054877},
  volume       = {45},
  year         = {2016},
}