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High-Fat Diet Reduces the Formation of Butyrate, but Increases Succinate, Inflammation, Liver Fat and Cholesterol in Rats, while Dietary Fibre Counteracts These Effects.

Jakobsdottir, Greta LU ; Xu, Jie LU ; Molin, Göran LU ; Ahrné, Siv LU and Nyman, Margareta LU (2013) In PLoS ONE 8(11).
Abstract
Obesity is linked to type 2 diabetes and risk factors associated to the metabolic syndrome. Consumption of dietary fibres has been shown to have positive metabolic health effects, such as by increasing satiety, lowering blood glucose and cholesterol levels. These effects may be associated with short-chain fatty acids (SCFAs), particularly propionic and butyric acids, formed by microbial degradation of dietary fibres in colon, and by their capacity to reduce low-grade inflammation.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
8
issue
11
publisher
Public Library of Science
external identifiers
  • wos:000327254700184
  • pmid:24236183
  • scopus:84893403953
ISSN
1932-6203
DOI
10.1371/journal.pone.0080476
language
English
LU publication?
yes
id
a7644443-fd1d-4532-9d0b-c8044768e71f (old id 4179324)
date added to LUP
2013-12-10 17:08:23
date last changed
2019-04-23 02:43:51
@article{a7644443-fd1d-4532-9d0b-c8044768e71f,
  abstract     = {Obesity is linked to type 2 diabetes and risk factors associated to the metabolic syndrome. Consumption of dietary fibres has been shown to have positive metabolic health effects, such as by increasing satiety, lowering blood glucose and cholesterol levels. These effects may be associated with short-chain fatty acids (SCFAs), particularly propionic and butyric acids, formed by microbial degradation of dietary fibres in colon, and by their capacity to reduce low-grade inflammation.},
  articleno    = {e80476},
  author       = {Jakobsdottir, Greta and Xu, Jie and Molin, Göran and Ahrné, Siv and Nyman, Margareta},
  issn         = {1932-6203},
  language     = {eng},
  number       = {11},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {High-Fat Diet Reduces the Formation of Butyrate, but Increases Succinate, Inflammation, Liver Fat and Cholesterol in Rats, while Dietary Fibre Counteracts These Effects.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0080476},
  volume       = {8},
  year         = {2013},
}