Advanced

Regional contribution to ventricular stroke volume is affected on the left side, but not on the right in patients with pulmonary hypertension

Ostenfeld, E. LU ; Stephensen, S. S. LU ; Steding-Ehrenborg, K. LU ; Heiberg, E. LU ; Arheden, H. LU ; Rådegran, G. LU ; Holm, J. LU and Carlsson, M. LU (2016) In International Journal of Cardiovascular Imaging 32(8). p.1243-1253
Abstract

To develop more sensitive measures of impaired cardiac function in patients with pulmonary hypertension (PH), since detection of impaired right ventricular (RV) function is important in these patients. With the hypothesis that a change in septal function in patients with PH is associated with altered longitudinal and lateral function of both ventricles, as a compensatory mechanism, we quantified the contributions of these parameters to stroke volume (SV) in both ventricles using cardiac magnetic resonance (CMR). Seventeen patients (10 females) evaluated for PH underwent right heart catheterization (RHC) and CMR. CMR from 33 healthy adults (13 females) were used as controls. Left ventricular (LV) atrioventricular plane displacement... (More)

To develop more sensitive measures of impaired cardiac function in patients with pulmonary hypertension (PH), since detection of impaired right ventricular (RV) function is important in these patients. With the hypothesis that a change in septal function in patients with PH is associated with altered longitudinal and lateral function of both ventricles, as a compensatory mechanism, we quantified the contributions of these parameters to stroke volume (SV) in both ventricles using cardiac magnetic resonance (CMR). Seventeen patients (10 females) evaluated for PH underwent right heart catheterization (RHC) and CMR. CMR from 33 healthy adults (13 females) were used as controls. Left ventricular (LV) atrioventricular plane displacement (AVPD) and corresponding longitudinal contribution to LVSV was lower in patients (10.8 ± 3.2 mm and 51 ± 12 %) compared to controls (16.6 ± 1.9 mm and 59 ± 9 %, p <0.0001 and p <0.01, respectively). This decrease did not differ in patient with ejection fraction (EF) >50 % and

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cardiac magnetic resonance imaging, Longitudinal function, Pulmonary hypertension, Right heart catheterization, RV pressure load, Septal and lateral function, Stroke volume
in
International Journal of Cardiovascular Imaging
volume
32
issue
8
pages
11 pages
publisher
Springer
external identifiers
  • scopus:84965011033
  • wos:000381284500010
ISSN
1569-5794
DOI
10.1007/s10554-016-0898-9
language
English
LU publication?
yes
id
d12b1c37-e830-4633-a704-ab67f6b38f86
date added to LUP
2016-06-01 16:59:40
date last changed
2017-01-01 08:27:28
@article{d12b1c37-e830-4633-a704-ab67f6b38f86,
  abstract     = {<p>To develop more sensitive measures of impaired cardiac function in patients with pulmonary hypertension (PH), since detection of impaired right ventricular (RV) function is important in these patients. With the hypothesis that a change in septal function in patients with PH is associated with altered longitudinal and lateral function of both ventricles, as a compensatory mechanism, we quantified the contributions of these parameters to stroke volume (SV) in both ventricles using cardiac magnetic resonance (CMR). Seventeen patients (10 females) evaluated for PH underwent right heart catheterization (RHC) and CMR. CMR from 33 healthy adults (13 females) were used as controls. Left ventricular (LV) atrioventricular plane displacement (AVPD) and corresponding longitudinal contribution to LVSV was lower in patients (10.8 ± 3.2 mm and 51 ± 12 %) compared to controls (16.6 ± 1.9 mm and 59 ± 9 %, p &lt;0.0001 and p &lt;0.01, respectively). This decrease did not differ in patient with ejection fraction (EF) &gt;50 % and </p>},
  author       = {Ostenfeld, E. and Stephensen, S. S. and Steding-Ehrenborg, K. and Heiberg, E. and Arheden, H. and Rådegran, G. and Holm, J. and Carlsson, M.},
  issn         = {1569-5794},
  keyword      = {Cardiac magnetic resonance imaging,Longitudinal function,Pulmonary hypertension,Right heart catheterization,RV pressure load,Septal and lateral function,Stroke volume},
  language     = {eng},
  number       = {8},
  pages        = {1243--1253},
  publisher    = {Springer},
  series       = {International Journal of Cardiovascular Imaging},
  title        = {Regional contribution to ventricular stroke volume is affected on the left side, but not on the right in patients with pulmonary hypertension},
  url          = {http://dx.doi.org/10.1007/s10554-016-0898-9},
  volume       = {32},
  year         = {2016},
}