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- 2020
- Health-related quality of life in transplant ineligible newly diagnosed multiple myeloma patients treated with either thalidomide or lenalidomide-based regimen until progression : A prospective, open-label, multicenter, randomized, phase 3 study
- Genetic predisposition for multiple myeloma
- Outcome and characteristics of non-measurable myeloma : A cohort study with population-based data from the Swedish Myeloma Registry
- Prognostic and predictive performance of R-ISS with SKY92 in older patients with multiple myeloma : The HOVON-87/NMSG-18 trial
- Search for multiple myeloma risk factors using Mendelian randomization
- International Myeloma Working Group risk stratification model for smoldering multiple myeloma (SMM)
- Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study
- 2019
- All-oral ixazomib, cyclophosphamide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma
-
Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis
Hellmark, Thomas LU
; Ohlsson, Sophie
LU
; Pettersson, Åsa
LU
; Hansson, Markus
LU
and Johansson, Åsa C M
LU
(2019)
In BMC Rheumatology
3(9).
Mark
- Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in Sweden
- Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes
- Exposure levels from radiology procedures used in myeloma diagnostics
- 2018
- A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia
-
Bone marrow eosinophils in plasma cell disorders
Wichert, Stina LU
; Pettersson, Åsa
LU
; Hellmark, Thomas
LU
; Johansson, Åsa
LU
and Hansson, Markus
LU
(2018)
In Experimental Hematology
66.
p.5-31
Mark
-
Whole-exome sequencing exploration of acquired uniparental disomies in B-cell precursor acute lymphoblastic leukemia
Lundin-Ström, Kristina B. LU ; Biloglav, Andrea LU ; Lilljebjörn, Henrik LU
; Rissler, Marianne
LU
; Fioretos, Thoas
LU
; Hansson, Markus
LU
; Behrendtz, Mikael
; Castor, Anders
LU
; Olsson, Linda
LU
and Johansson, Bertil
LU
(2018)
In Leukemia
32(9).
p.2058-2062
Mark
- Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
- Lenalidomide versus lenalidomide + dexamethasone prolonged treatment after second-line lenalidomide + dexamethasone induction in multiple myeloma
- The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression
- Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology
- 2017
-
A single-arm, open-label, phase 2 clinical trial evaluating disease response following treatment with BI-505, a human anti-intercellular adhesion molecule-1 monoclonal antibody, in patients with smoldering multiple myeloma
Wichert, Stina LU
; Juliusson, Gunnar
LU
; Johansson, Åsa
LU
; Sonesson, Elisabeth
; Teige, Ingrid
; Wickenberg, Anna Teige
; Frendeus, Björn
; Korsgren, Magnus
and Hansson, Markus
LU
(2017)
In PLoS ONE
12(2).
Mark
-
Identification of sequence variants influencing immunoglobulin levels
Jonsson, Stefan ; Sveinbjornsson, Gardar ; de Lapuente Portilla, Aitzkoa Lopez LU ; Swaminathan, Bhairavi LU ; Plomp, Rosina ; Dekkers, Gillian ; Ajore, Ram LU ; Ali, Mina LU ; Bentlage, Arthur E H and Elmér, Evelina LU
, et al.
(2017)
In Nature Genetics
49(8).
p.1182-1191
Mark
- Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach
- Impact of prior therapy on the efficacy and safety of oral ixazomib-lenalidomide-dexamethasone vs. placebo-lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma in TOURMALINE-MM1
- NOX2-dependent immunosuppression in chronic myelomonocytic leukemia
- Direct evidence for a polygenic etiology in familial multiple myeloma
- Natural history of relapsed myeloma, refractory to immunomodulatory drugs and proteasome inhibitors : a multicenter IMWG study
- Incidence, characteristics, and outcome of solitary plasmacytoma and plasma cell leukemia. Population-based data from the Swedish Myeloma Register
- Adverse event management in patients with relapsed and refractory multiple myeloma taking pomalidomide plus low-dose dexamethasone : A pooled analysis
- 2016
-
Phagocyte Function Decreases after High-Dose Treatment with Melphalan and Autologous Stem Cell Transplantation in Patients with Multiple Myeloma.
Wichert, Stina LU
; Pettersson, Åsa
LU
; Hellmark, Thomas
LU
; Johansson, Åsa
LU
and Hansson, Markus
LU
(2016)
In Experimental Hematology
44(5).
p.342-351
Mark
- Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
-
Impaired phagocytosis and reactive oxygen species production in phagocytes is associated with systemic vasculitis
Johansson, Åsa Cm LU ; Ohlsson, Sophie LU
; Pettersson, Åsa
LU
; Bengtsson, Anders
LU
; Selga, Daina
LU
; Hansson, Markus
LU
and Hellmark, Thomas
LU
(2016)
In Arthritis Research & Therapy
18.
Mark
- Melphalan, prednisone, and lenalidomide versus melphalan, prednisone, and thalidomide in untreated multiple myeloma.
- Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010) : A phase 3b study in refractory multiple myeloma
- Cost effectiveness of pomalidomide in patients with relapsed and refractory multiple myeloma in Sweden
- Oral Ixazomib, lenalidomide, and dexamethasone for multiple myeloma
- 2015
-
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.
Swaminathan, Bhairavi LU ; Thorleifsson, Guðmar ; Jöud, Magnus LU
; Ali, Mina
LU
; Johnsson, Ellinor
LU
; Ajore, Ram
LU
; Sulem, Patrick
; Halvarsson, Britt-Marie
LU
; Eyjolfsson, Guðmundur
and Haraldsdottir, Vilhelmina
, et al.
(2015)
In Nature Communications
6.
p.1-8
Mark
- Antagonistic Human FcγRIIB (CD32B) Antibodies Have Anti-Tumor Activity and Overcome Resistance to Antibody Therapy In Vivo.
- A phase 1 dose-escalation study of antibody BI-505 in relapsed/refractory multiple myeloma.
- Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.
- Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma.
- 2014
- Robust isolation of malignant plasma cells in multiple myeloma.
-
Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus
Bengtsson, Anders LU ; Pettersson, Åsa LU ; Wichert, Stina LU
; Gullstrand, Birgitta
LU
; Hansson, Markus
LU
; Hellmark, Thomas
LU
and Johansson, Åsa
LU
(2014)
In Arthritis Research and Therapy
16(3).
Mark
- Expert panel consensus statement on the optimal use of pomalidomide in relapsed and refractory multiple myeloma.
- 2013
- A human icam-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo.
- 2012
- Remission maintenance in acute myeloid leukemia: impact of functional histamine H-2 receptors expressed by leukemic cells
- Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis
- 2010
-
Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells.
Källquist, Linda LU ; Rosén, Hanna ; Nordenfelt, Pontus LU
; Calafat, Jero
; Janssen, Hans
; Persson, Ann-Maj
LU
; Hansson, Markus
LU
and Olsson, Inge
LU
(2010)
In Experimental Cell Research
Okt.
p.3182-3196
Mark
- 2009
- Secretory lysosome targeting and induced secretion of human soluble TNF-alpha receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy.
- 2008
- The tetraspanin CD63 is involved in granule targeting of neutrophil elastase.
- 2007
- Biphenotypic bigenotypic lymphoma with simultaneous expression of PAX5/BSAP and B- and T-cell markers
- 2006
- Granule targeting of soluble tumor necrosis factor (TNF) receptor expressed during granulopoietic maturation in murine bone marrow cells.
- Neutrophil elastase sorting involves plasma membrane trafficking requiring the C-terminal propeptide.
- Biosynthesis, processing, and sorting of human myeloperoxidase.
- 2005
- Reactivation of latent Epstein Barr virus infection induces remission of splenic lymphoma with villous lymphocytes.
- 2004
- Activation of cytotoxic lymphocytes by interferon-{alpha}: role of oxygen radical-producing mononuclear phagocytes.
- Hematopoietic secretory granules as vehicles for the local delivery of cytokines and soluble cytokine receptors at sites of inflammation.
- Sorting soluble tumor necrosis factor (TNF) receptor for storage and regulated secretion in hematopoietic cells.
- Biosynthesis and sorting of myeloperoxidase in hematopoietic cells.
- 2003
- Targeting proteins to secretory lysosomes of natural killer cells as a principle for immunoregulation.