Experimental Epilepsy Group
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- 2024
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Mark
Collagen VI : Role in synaptic transmission and seizure-related excitability
(
- Contribution to journal › Article
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Mark
Presynaptic nanoscale components of retrograde synaptic signaling
(
- Contribution to journal › Article
- 2023
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Mark
Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
(
- Contribution to journal › Article
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Mark
Neuronal activity dynamics in the dentate gyrus during early epileptogenesis
(
- Contribution to journal › Article
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Mark
Optogenetics for controlling seizure circuits for translational approaches
(
- Contribution to journal › Article
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Mark
Shaping the future of European epilepsy research : Final meeting report from EPICLUSTER
(
- Contribution to journal › Article
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Mark
Cell-specific switch for epileptiform activity : critical role of interneurons in the mouse subicular network
(
- Contribution to journal › Article
- 2022
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Mark
Development and preclinical assessment of novel therapies for Epilepsy. Exploring the potential of human-derived cell lines and glial cell line-derived neurotrophic factor for network inhibition.
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
Transcription factor-based direct conversion of human fibroblasts to functional astrocytes
(
- Contribution to journal › Article
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Mark
Lipid mediator n-3 docosapentaenoic acid-derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G-protein-coupled receptor
(
- Contribution to journal › Article
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Mark
GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway
(
- Contribution to journal › Article
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Mark
Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders
2022) In Journal of visualized experiments : JoVE(
- Contribution to journal › Article
- 2021
-
Mark
Meeting report : EpiXchange II brings together European epilepsy research projects to discuss latest advances
(
- Contribution to journal › Letter
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Mark
Editorial : Gene Therapy in the CNS – Progress and Prospects for Novel Therapies
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Human stem cell‐derived gabaergic interneurons establish efferent synapses onto host neurons in rat epileptic hippocampus and inhibit spontaneous recurrent seizures
(
- Contribution to journal › Article
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Mark
Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks
(
- Contribution to journal › Article
- 2020
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Mark
Advancing gene therapy for epilepsy. Translational pre-clinical studies with neuropeptide Y and glial cell-line derived neurotrophic factor.
2020) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons
(
- Contribution to journal › Article
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Mark
Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy : Preclinical Data in Rats
(
- Contribution to journal › Article
- 2019
-
Mark
Unilateral ex vivo gene therapy by GDNF in epileptic rats
(
- Contribution to journal › Article
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Mark
Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy
2019) In Epilepsia(
- Contribution to journal › Article
-
Mark
Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy
2019) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 39(11). p.2144-2156(
- Contribution to journal › Article
-
Mark
Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients
(
- Contribution to journal › Article
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Mark
Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons
(
- Contribution to journal › Article
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Mark
Disease Modification by Combinatorial Single Vector Gene Therapy : A Preclinical Translational Study in Epilepsy
(
- Contribution to journal › Article
- 2018
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Mark
Bridging the gap in translational epilepsy research - A patient brain tissue platform for validating animal data
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Preserved function of afferent parvalbumin-positive perisomatic inhibitory synapses of dentate granule cells in rapidly kindled mice
(
- Contribution to journal › Article
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Mark
Spatiotemporal pattern of Wnt-canonical pathway in dorsal telencephalic organoids.
2018)(
- Contribution to conference › Poster
- 2017
-
Mark
Epilepsy and optogenetics : Can seizures be controlled by light?
(
- Contribution to journal › Scientific review
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Mark
Altered chloride homeostasis decreases the action potential threshold and increases hyperexcitability in hippocampal neurons
(
- Contribution to journal › Article
- 2016
-
Mark
Novel approaches to explore mechanisms of epileptic seizures - optogenetic and chemogenetic manipulation of hippocampal circuitry
(
- Thesis › Doctoral thesis (compilation)
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Mark
Optogenetic control of human neurons in organotypic brain cultures
(
- Contribution to journal › Article
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Mark
DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue
(
- Contribution to journal › Article
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Mark
Advances in the development of biomarkers for epilepsy
(
- Contribution to journal › Scientific review
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Mark
Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors.
(
- Contribution to journal › Article
- 2015
-
Mark
Chemogenetics, Induced Neurons and Pluripotent Stem Cells: Towards Advanced Gene and Cell Therapies Targeting Epilepsy
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus.
(
- Contribution to journal › Article
- 2014
-
Mark
A compact multifunctional microfluidic platform for exploring cellular dynamics in real-time using electrochemical detection
(
- Contribution to journal › Article
-
Mark
Quantitative mapping of the local and extrinsic sources of GABA and Reelin to the layer Ia neuropil in the adult rat neocortex
(
- Contribution to journal › Article
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Mark
Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity.
(
- Contribution to journal › Article
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Mark
Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.
(
- Contribution to journal › Article
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Mark
Optogenetics reveal delayed afferent synaptogenesis on grafted human induced pluripotent stem cell-derived neural progenitors.
(
- Contribution to journal › Article
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Mark
How Might Novel Technologies Such as Optogenetics Lead to Better Treatments in Epilepsy?
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2013
-
Mark
Epilepsy therapy development: Technical and methodologic issues in studies with animal models
(
- Contribution to journal › Article
- 2012
-
Mark
VEGF receptor-2 (flk-1) overexpression in mice counteracts focal epileptic seizures.
(
- Contribution to journal › Article
-
Mark
Altered profile of basket cell afferent synapses in hyper-excitable dentate gyrus revealed by optogenetic and two-pathway stimulations.
(
- Contribution to journal › Article
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Mark
Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures
(
- Contribution to journal › Article
- 2011
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Mark
Tuning afferent synapses of hippocampal interneurons by neuropeptide Y.
(
- Contribution to journal › Article
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Mark
Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model.
(
- Contribution to journal › Article
- 2010
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Mark
Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.
(
- Contribution to journal › Article
- 2009
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Mark
Optogenetic control of epileptiform activity.
(
- Contribution to journal › Article
- 2008
-
Mark
Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in subiculum
(
- Contribution to journal › Article
-
Mark
Gene therapy for epilepsy: resculpturing synaptic transmission with neuropeptides
(
- Thesis › Doctoral thesis (compilation)
- 2007
-
Mark
Brain area, age and viral vector-specific glial cell-line-derived neurotrophic factor expression and transport in rat.
(
- Contribution to journal › Article
-
Mark
Seizure Suppression by GDNF Gene Therapy in Animal Models of Epilepsy.
(
- Contribution to journal › Article
- 1989
-
Mark
Ethanol stimulates basal and serotonin-induced formation of [32P]phosphatidic acid in human platelets
(
- Contribution to journal › Article