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- 2024
-
Mark
Preventive cognitive protection based on AAV9 overexpression of IGF1 in hippocampal astrocytes
(
- Contribution to journal › Article
- 2023
-
Mark
Mutant huntingtin expression in the hypothalamus promotes ventral striatal neuropathology
2023)(
- Working paper/Preprint › Preprint in preprint archive
-
Mark
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants
in vivo.
(
- Contribution to journal › Article
-
Mark
Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling
(
- Contribution to journal › Article
- 2022
-
Mark
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants
(
- Contribution to journal › Article
- 2021
-
Mark
Next-Generation Gene Therapy for Parkinson's Disease Using Engineered Viral Vectors
(
- Contribution to journal › Scientific review
-
Mark
FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation
(
- Contribution to journal › Article
-
Mark
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy?
(
- Contribution to journal › Scientific review
- 2020
-
Mark
AAV Production Everywhere : A Simple, Fast, and Reliable Protocol for In-house AAV Vector Production Based on Chloroform Extraction
(
- Contribution to journal › Article
- 2019
-
Mark
Practical Considerations for the Use of DREADD and Other Chemogenetic Receptors to Regulate Neuronal Activity in the Mammalian Brain
(
- Contribution to journal › Article
-
Mark
Seeding of protein aggregation causes cognitive impairment in rat model of cortical synucleinopathy
(
- Contribution to journal › Article
-
Mark
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
2019) In Proceedings of the National Academy of Sciences of the United States of America 116(52). p.27053-27062(
- Contribution to journal › Article
- 2018
-
Mark
Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum
(
- Contribution to journal › Article
-
Mark
Repairing the brain : Gene therapy
(
- Contribution to journal › Scientific review
-
Mark
Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing
(
- Contribution to journal › Article
-
Mark
A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency
(
- Contribution to journal › Article
- 2016
-
Mark
Expression of Multiple Functional RNAs or Proteins from One Viral Vector.
(
- Contribution to journal › Article
-
Mark
Identification of multiple QTLs linked to neuropathology in the engrailed-1 heterozygous mouse model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
A novel process of viral vector barcoding and library preparation enables high-diversity library generation and recombination-free paired-end sequencing
(
- Contribution to journal › Article
-
Mark
Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level
(
- Contribution to journal › Article
-
Mark
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
(
- Contribution to journal › Article
- 2014
-
Mark
Novel AAV-Based Rat Model of Forebrain Synucleinopathy Shows Extensive Pathologies and Progressive Loss of Cholinergic Interneurons.
(
- Contribution to journal › Article
-
Mark
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.
(
- Contribution to journal › Article
- 2013
-
Mark
Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
(
- Contribution to journal › Article
- 2012
-
Mark
Dysregulated dopamine storage increases the vulnerability to alpha-synuclein in nigral neurons
(
- Contribution to journal › Article
-
Mark
Design of a Single AAV Vector for Coexpression of TH and GCH1 to Establish Continuous DOPA Synthesis in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
- 2011
-
Mark
Gene therapy for Parkinson's disease shows promise.
(
- Contribution to journal › Article
-
Mark
Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits.
(
- Contribution to journal › Article
- 2010
-
Mark
A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System
(
- Contribution to journal › Article
-
Mark
Differential Transduction Following Basal Ganglia Administration of Distinct Pseudotyped AAV Capsid Serotypes in Nonhuman Primates
(
- Contribution to journal › Article
-
Mark
Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Gene therapy for Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Gene therapy for dopamine replacement.
(
- Contribution to journal › Scientific review
- 2009
-
Mark
Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons.
(
- Contribution to journal › Article
-
Mark
Optimization of continuous in vivo DOPA production and studies on ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats
(
- Contribution to journal › Article
-
Mark
Positron Emission Tomography Imaging Demonstrates Correlation between Behavioral Recovery and Correction of Dopamine Neurotransmission after Gene Therapy
(
- Contribution to journal › Article
-
Mark
Gene therapy by enzyme replacement for Parkinson’s disease Optimization of continuous DOPA delivery and development of a candidate vector for clinical application
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Gene therapy for dopamine replacement in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Scientific rationale for the development of gene therapy strategies for Parkinson's disease.
(
- Contribution to journal › Article
- 2008
-
Mark
In vivo gene delivery for development of mammalian models for Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
Applications of lentiviral vectors for biology and gene therapy of neurological disorders.
(
- Contribution to journal › Article
-
Mark
Future Cell- and Gene-Based Therapies for Parkinson's Disease
2008) p.145-156(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2007
-
Mark
Restoration of the striatal dopamine synthesis for Parkinson's disease: viral vector-mediated enzyme replacement strategy.
(
- Contribution to journal › Scientific review
-
Mark
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.
(
- Contribution to journal › Article
- 2006
-
Mark
Morphometric and psychometric comparisons between non-substance-abusing patients with posttraumatic stress disorder and normal controls
(
- Contribution to journal › Letter
- 2005
-
Mark
Imaging in cell-based therapy for neurodegenerative diseases.
(
- Contribution to journal › Scientific review