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- 2023
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Mark
Functional and molecular profiling of hematopoietic stem cells during regeneration
(
- Contribution to journal › Article
- 2022
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Mark
Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
(
- Contribution to journal › Article
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Mark
Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector
(
- Contribution to journal › Article
- 2021
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Mark
Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype
(
- Contribution to journal › Article
-
Mark
BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
(
- Contribution to journal › Article
- 2020
-
Mark
S100A6 is a critical regulator of hematopoietic stem cells.
2020) In Leukemia(
- Contribution to journal › Article
- 2017
-
Mark
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
(
- Contribution to journal › Article
- 2016
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Mark
A network including TGFβ/Smad4, Gata2 and p57 regulates proliferation of mouse hematopoietic progenitor cells.
(
- Contribution to journal › Article
- 2015
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Mark
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
(
- Contribution to journal › Article
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Mark
Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy
(
- Contribution to journal › Article
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Mark
TGF-β signaling in the control of hematopoietic stem cells.
(
- Contribution to journal › Article
- 2014
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Mark
The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease
(
- Contribution to journal › Article
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Mark
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
(
- Contribution to journal › Article
- 2013
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Mark
Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease
(
- Contribution to journal › Article
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Mark
Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes
(
- Contribution to journal › Article
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Mark
B cell lymphoma and myeloma in murine Gaucher's disease
(
- Contribution to journal › Article
- 2012
-
Mark
Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions
(
- Contribution to journal › Article
-
Mark
Angptl4 maintains in vivo repopulation capacity of CD34(+) human cord blood cells.
(
- Contribution to journal › Article
-
Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo.
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche.
(
- Contribution to journal › Article
- 2011
-
Mark
Stress hematopoiesis requires Erg
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
(
- Contribution to journal › Article
-
Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
(
- Contribution to journal › Article
- 2010
-
Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
(
- Contribution to journal › Published meeting abstract
-
Mark
Cripto Selectively Expands a Distinct Population of Hematopoietic Stem Cells Expressing the Cell Surface Receptor GRP78 and Strongly Induces An Immature Phenotype In Vivo After Ex Vivo Culture
(
- Contribution to journal › Published meeting abstract
-
Mark
Cripto Selectively Expands a Distinct Population Of Hematopoietic Stem Cells Expressing Cell Surface Receptor GRP78
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.038-038(
- Contribution to journal › Published meeting abstract
-
Mark
High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event
(
- Contribution to journal › Published meeting abstract
-
Mark
SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation
(
- Contribution to journal › Published meeting abstract
-
Mark
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
(
- Contribution to journal › Article
- 2009
-
Mark
In an inducible model of acute myeloid leukemia, secondary hits are required to generate a leukemia relapse after removal of the initial transforming event
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.16-16(
- Contribution to journal › Published meeting abstract
-
Mark
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition
(
- Contribution to journal › Published meeting abstract
-
Mark
Lipocalin 2 negatively controls erythroid and macrophage lineages via megalin as its receptor
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.80-81(
- Contribution to journal › Published meeting abstract
-
Mark
Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation
(
- Contribution to journal › Article
-
Mark
SMAD4 as a therapeutic target in hoxa9-related leukemia
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.44-45(
- Contribution to journal › Published meeting abstract
-
Mark
Is TGF-beta a stemness regulator?
(
- Contribution to journal › Article
-
Mark
Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling.
(
- Contribution to journal › Scientific review
- 2008
-
Mark
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference
(
- Contribution to journal › Scientific review
-
Mark
A HOXA10-inducible mouse model demonstrates an important role of the initial transforming event in the maintenance of the leukemia
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.4-5(
- Contribution to journal › Published meeting abstract
-
Mark
Therapeutic effects of bone marrow transplantation for metachromatic leukodystrophy using HOXB4 over-expressing cells
2008) The 13th Annual Meeting 2007 Japan Society of Gene Therapy In Journal of Gene Medicine 10(4). p.476-477(
- Contribution to journal › Published meeting abstract
-
Mark
Clonal mar-king and genetic manipulation of AGM HSCs
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.69-69(
- Contribution to journal › Published meeting abstract
-
Mark
Smad4 as a Therapeutic Target in Nup98-HoxA9-Induced Leukemia.
(
- Contribution to journal › Published meeting abstract
-
Mark
A critical role for Smad4 in the self-renewal of hematopoietic stem cells
2008) 4th Conference on Stem Cell Gene Therapy In Blood Cells, Molecules, and Diseases 40(2). p.271-271(
- Contribution to journal › Published meeting abstract
-
Mark
Enforced expression of c-Ski in adult murine hematopoiesis promotes myeloid - Differentiation, revealing an important role for c-Ski in governing hematopoietic cell fate options
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.29-29(
- Contribution to journal › Published meeting abstract
-
Mark
Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.
(
- Contribution to journal › Article
-
Mark
Signaling pathways governing stem cell fate.
(
- Contribution to journal › Scientific review
- 2007
-
Mark
Connecting ribosomes with bone marrow failure
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Diamond-Blackfan anemia: erythropoiesis lost in translation.
(
- Contribution to journal › Scientific review
-
Mark
HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cell targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice.
(
- Contribution to journal › Article
-
Mark
Adenoviral vectors for transient gene expression in human primitive hematopoietic cells: Applications and prospects.
(
- Contribution to journal › Scientific review
-
Mark
Murine models of acute neuronopathic Gaucher disease
(
- Contribution to journal › Article
-
Mark
Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects
(
- Contribution to journal › Article
-
Mark
Human RPS19, the gene mutated in Diamond Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits.
(
- Contribution to journal › Article
-
Mark
Smad4 is critical for self-renewal of hematopoietic stem cells.
(
- Contribution to journal › Article
- 2006
-
Mark
Erythropoiesis in the Rps19 disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia
(
- Contribution to journal › Article
-
Mark
Smad7 promotes self-renewal of hematopoietic stem cells in vivo.
(
- Contribution to journal › Article
-
Mark
Neonatal hematopoietic stem cell transplantation cures oc/oc mice from osteopetrosis.
(
- Contribution to journal › Article
-
Mark
Effective cell and gene therapy in a murine model of Gaucher disease.
(
- Contribution to journal › Article
-
Mark
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion
(
- Contribution to journal › Article
-
Mark
Smad5 is dispensable for adult murine hematopoiesis.
(
- Contribution to journal › Article
- 2005
-
Mark
Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-beta signaling in vivo.
(
- Contribution to journal › Article
-
Mark
Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
TGF-{beta} type II receptor deficient thymocytes develop normally but demonstrate increased CD8+ proliferation in vivo.
(
- Contribution to journal › Article
-
Mark
Gene therapy: efficient targeting of hematopoietic stem cells
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells
(
- Contribution to journal › Article
-
Mark
Gene expression profiling demonstrates that TGF-{beta}1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-{beta} signaling.
(
- Contribution to journal › Article
- 2004
-
Mark
Stem cell expansion: success and complexities
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction
(
- Contribution to journal › Article
-
Mark
Enforced expression of cyclin D2 enhances the proliferative potential of myeloid progenitors, accelerates in vivo myeloid reconstitution, and promotes rescue of mice from lethal myeloablation.
(
- Contribution to journal › Article
-
Mark
Development of an adenoviral vector system with adenovirus serotype 35 tropism; efficient transient gene transfer into primary malignant hematopoietic cells.
(
- Contribution to journal › Article
-
Mark
Overexpression of CXCR4 on human CD34(+) progenitors increases their proliferation, migration, and NOD/SCID repopulation
(
- Contribution to journal › Article
-
Mark
Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantation
(
- Contribution to journal › Article
- 2003
-
Mark
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFP/ALK5 signaling
(
- Contribution to journal › Article
-
Mark
TGF-{beta} signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro.
(
- Contribution to journal › Article
-
Mark
Reduced proliferative capacity of hematopoietic stem cells deficient in hoxb3 and hoxb4.
(
- Contribution to journal › Article
-
Mark
Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis.
(
- Contribution to journal › Article
-
Mark
Bakslag for genterapi: två fall av leukemi i fransk studie [Setback for gene therapy: Two cases of leukemia in a French trial]
(
- Contribution to journal › Article
-
Mark
Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing
2003) HEMATOPOIETIC STEM CELLS 2002: GENETICS AND FUNCTION: Fourth International Symposium 996. p.112-121(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
- 2002
-
Mark
Oncoretroviral gene transfer to NOD/SCID repopulating cells using three different viral envelopes
(
- Contribution to journal › Article
-
Mark
Gene transfer improves erythroid development in ribosomal protein S19-deficient Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Development of gene therapy for blood disorders by gene transfer into haematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable.
(
- Contribution to journal › Article
-
Mark
Framgangsrik genterapi av barn med svar immundefekt. Forskningsgenombrott ger hopp om behandling aven av andra sjukdomar
(
- Contribution to journal › Article
- 2001
-
Mark
High-titer lentivirus mediated gene transfer introduces multiple vector copies into the genome of primate and human hematopoietic repopulating cells
(
- Contribution to journal › Article
-
Mark
Retroviral transduction of human CD34+ cells on fibronectin fragment CH-296 is inhibited by high concentrations of vector containing medium
(
- Contribution to journal › Article
-
Mark
Proliferation of primitive myeloid progenitors can be reversibly induced by HOXA10
(
- Contribution to journal › Article
-
Mark
Clinical gene therapy in hematology: Past and future
(
- Contribution to journal › Article
- 2000
-
Mark
Low level of gene transfer to and engraftment of murine bone marrow cells from long-term bone marrow cultures
(
- Contribution to journal › Article
- 1996
-
Mark
Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution
1996) In Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 114(3). p.303-311(
- Contribution to journal › Article