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- 2023
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Mark
Functional and molecular profiling of hematopoietic stem cells during regeneration
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- Contribution to journal › Article
- 2022
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Mark
Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector
(
- Contribution to journal › Article
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Mark
Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
(
- Contribution to journal › Article
- 2021
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Mark
Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype
(
- Contribution to journal › Article
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Mark
BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
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- Contribution to journal › Article
- 2020
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Mark
S100A6 is a critical regulator of hematopoietic stem cells.
2020) In Leukemia(
- Contribution to journal › Article
- 2017
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Mark
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
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- Contribution to journal › Article
- 2016
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Mark
A network including TGFβ/Smad4, Gata2 and p57 regulates proliferation of mouse hematopoietic progenitor cells.
(
- Contribution to journal › Article
- 2015
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Mark
Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy
(
- Contribution to journal › Article
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Mark
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
(
- Contribution to journal › Article
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Mark
TGF-β signaling in the control of hematopoietic stem cells.
(
- Contribution to journal › Article
- 2014
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Mark
The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease
(
- Contribution to journal › Article
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Mark
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
(
- Contribution to journal › Article
- 2013
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Mark
Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease
(
- Contribution to journal › Article
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Mark
B cell lymphoma and myeloma in murine Gaucher's disease
(
- Contribution to journal › Article
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Mark
Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes
(
- Contribution to journal › Article
- 2012
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Mark
Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions
(
- Contribution to journal › Article
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Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
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Mark
Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo.
(
- Contribution to journal › Article
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Mark
Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche.
(
- Contribution to journal › Article
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Mark
Angptl4 maintains in vivo repopulation capacity of CD34(+) human cord blood cells.
(
- Contribution to journal › Article
- 2011
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Mark
Stress hematopoiesis requires Erg
(
- Contribution to journal › Debate/Note/Editorial
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Mark
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
(
- Contribution to journal › Article
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Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
(
- Contribution to journal › Article
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Mark
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
(
- Contribution to journal › Article
- 2010
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Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
(
- Contribution to journal › Published meeting abstract
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Mark
Cripto Selectively Expands a Distinct Population of Hematopoietic Stem Cells Expressing the Cell Surface Receptor GRP78 and Strongly Induces An Immature Phenotype In Vivo After Ex Vivo Culture
(
- Contribution to journal › Published meeting abstract
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Mark
Cripto Selectively Expands a Distinct Population Of Hematopoietic Stem Cells Expressing Cell Surface Receptor GRP78
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.038-038(
- Contribution to journal › Published meeting abstract
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Mark
High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event
(
- Contribution to journal › Published meeting abstract
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Mark
SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation
(
- Contribution to journal › Published meeting abstract
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Mark
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
(
- Contribution to journal › Article
- 2009
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Mark
SMAD4 as a therapeutic target in hoxa9-related leukemia
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.44-45(
- Contribution to journal › Published meeting abstract
-
Mark
Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation
(
- Contribution to journal › Article
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Mark
Lipocalin 2 negatively controls erythroid and macrophage lineages via megalin as its receptor
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.80-81(
- Contribution to journal › Published meeting abstract
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Mark
Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling.
(
- Contribution to journal › Scientific review
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Mark
Is TGF-beta a stemness regulator?
(
- Contribution to journal › Article
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Mark
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition
(
- Contribution to journal › Published meeting abstract
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Mark
In an inducible model of acute myeloid leukemia, secondary hits are required to generate a leukemia relapse after removal of the initial transforming event
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.16-16(
- Contribution to journal › Published meeting abstract
- 2008
-
Mark
A critical role for Smad4 in the self-renewal of hematopoietic stem cells
2008) 4th Conference on Stem Cell Gene Therapy In Blood Cells, Molecules, and Diseases 40(2). p.271-271(
- Contribution to journal › Published meeting abstract
-
Mark
Enforced expression of c-Ski in adult murine hematopoiesis promotes myeloid - Differentiation, revealing an important role for c-Ski in governing hematopoietic cell fate options
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.29-29(
- Contribution to journal › Published meeting abstract
-
Mark
Clonal mar-king and genetic manipulation of AGM HSCs
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.69-69(
- Contribution to journal › Published meeting abstract
-
Mark
Smad4 as a Therapeutic Target in Nup98-HoxA9-Induced Leukemia.
(
- Contribution to journal › Published meeting abstract
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Mark
A HOXA10-inducible mouse model demonstrates an important role of the initial transforming event in the maintenance of the leukemia
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.4-5(
- Contribution to journal › Published meeting abstract
-
Mark
Therapeutic effects of bone marrow transplantation for metachromatic leukodystrophy using HOXB4 over-expressing cells
2008) The 13th Annual Meeting 2007 Japan Society of Gene Therapy In Journal of Gene Medicine 10(4). p.476-477(
- Contribution to journal › Published meeting abstract
-
Mark
Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.
(
- Contribution to journal › Article
-
Mark
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference
(
- Contribution to journal › Scientific review
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Mark
Signaling pathways governing stem cell fate.
(
- Contribution to journal › Scientific review
- 2007
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Mark
Human RPS19, the gene mutated in Diamond Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits.
(
- Contribution to journal › Article
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Mark
Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects
(
- Contribution to journal › Article
-
Mark
Adenoviral vectors for transient gene expression in human primitive hematopoietic cells: Applications and prospects.
(
- Contribution to journal › Scientific review