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- 2024
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Mark
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
2024) In Journal of Medicinal Chemistry(
- Contribution to journal › Article
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Mark
Interplay of halogen bonding and solvation in protein-ligand binding
(
- Contribution to journal › Article
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Mark
Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket
(
- Contribution to journal › Article
- 2023
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Mark
Discovery of Selective and Orally Available Galectin-1 Inhibitors
(
- Contribution to journal › Article
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Mark
Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds
(
- Contribution to journal › Article
- 2022
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Mark
Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors
(
- Contribution to journal › Article
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Mark
Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia
(
- Contribution to journal › Article
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Mark
Galectin-9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix
(
- Contribution to journal › Article
- 2021
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Mark
Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain : Structure-based design and optimisation
(
- Contribution to journal › Article
- 2020
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Mark
Epimers Switch Galectin-9 Domain Selectivity : 3 N-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal
(
- Contribution to journal › Article
- 2019
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Mark
Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors
(
- Contribution to journal › Article
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Mark
Stereo- And regioselective hydroboration of 1-exo-methylene pyranoses : Discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors
(
- Contribution to journal › Article
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Mark
C1-Galactopyranosyl Heterocycle Structure Guides Selectivity : Triazoles Prefer Galectin-1 and Oxazoles Prefer Galectin-3
(
- Contribution to journal › Article
- 2018
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Mark
Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity
(
- Contribution to journal › Article
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Mark
Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions
(
- Contribution to journal › Article
- 2016
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Mark
Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3 '-sulfo-lactose, and 2 '-fucosyllactose
(
- Contribution to journal › Article
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Mark
A Selective Galactose–Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model
(
- Contribution to journal › Article
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Mark
Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition
(
- Contribution to journal › Article
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Mark
Galactose-amidine derivatives as selective antagonists of galectin-9
(
- Contribution to journal › Article
- 2013
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Mark
Tuning the Preference of Thiodigalactoside- and Lactosamine-Based Ligands to Galectin-3 over Galectin-1
(
- Contribution to journal › Article