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- 2024
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Mark
Development of a novel AAK1 inhibitor via Kinobeads-based screening
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- Contribution to journal › Article
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Myocardin related transcription factor and galectin-3 drives lipid accumulation in human blood vessels
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- Contribution to journal › Article
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Mark
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
2024) In Journal of Medicinal Chemistry(
- Contribution to journal › Article
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Mark
Galectin-8 inhibition and functions in immune response and tumor biology
2024) In Medicinal Research Reviews(
- Contribution to journal › Scientific review
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Mark
Interplay of halogen bonding and solvation in protein-ligand binding
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- Contribution to journal › Article
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Galectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double π-Stack in a Unique Pocket
(
- Contribution to journal › Article
- 2023
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Mark
N-BAR and F-BAR proteins - Endophilin-A3 and PSTPIP1 - control clathrin-independent endocytosis of L1CAM
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- Contribution to journal › Article
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Mark
Evaluating the affinity and kinetics of small molecule glycomimetics for human and mouse galectin-3 using surface plasmon resonance
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- Contribution to journal › Article
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Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human neutrophils
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- Contribution to journal › Article
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Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor : a single- and multiple-dose first-in-human study in healthy participants
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- Contribution to journal › Article
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Mark
Galectin-8 Downmodulates TLR4 Activation and Impairs Bacterial Clearance in a Mouse Model of Pseudomonas aeruginosa Keratitis
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- Contribution to journal › Article
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Mark
Discovery of Selective and Orally Available Galectin-1 Inhibitors
(
- Contribution to journal › Article
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Mark
Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
(
- Contribution to journal › Article
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Mark
Resistance to anti-PD-1/anti-PD-L1 : galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1
(
- Contribution to journal › Article
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Mark
Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds
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- Contribution to journal › Article
- 2022
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Mark
Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside
(
- Contribution to journal › Article
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Mark
Direct Sialic Acid 4-OAc Substitution by Nitrogen, Sulfur and Carbon Nucleophiles with Retention of Stereochemistry
(
- Contribution to journal › Article
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Mark
Sialic Acid 4-N-Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter
(
- Contribution to journal › Article
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Mark
Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth
(
- Contribution to journal › Article
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Mark
Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors
(
- Contribution to journal › Article