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Difficulties in Translating Appetite Sensations Effect of Turmeric-Based Beverage When Given Prior to Isoenergetic Medium- or High-Fat Meals in Healthy Subjects

Zanzer, Yoghatama Cindya LU ; Batista, Ângela Giovana LU ; Dougkas, Anestis LU ; Tovar, Juscelino LU orcid ; Granfeldt, Yvonne LU and Östman, Elin LU (2019) In Nutrients 11(4).
Abstract

The established effect of turmeric and its curcuminoids on appetite sensations was previously shown to be mediated by gut hormones release. In in vitro and preclinical studies, curcumin was shown to induce GLP-1 secretion and improve postprandial glycemia. In humans, consumption of 220 mL turmeric-based beverage (TUR, containing 185 mg gallic acid equivalents (GAE)) prior to white wheat bread (WWB, 50 g available carbohydrate) reduced early postprandial glucose levels and induced peptide tyrosine⁻tyrosine (PYY) release, as well as lowered 'desire to eat' and 'prospective consumption' in a postprandial setting, compared to control. In the present study, 12 healthy participants (5 men, 7 women) were admitted. An identical beverage was... (More)

The established effect of turmeric and its curcuminoids on appetite sensations was previously shown to be mediated by gut hormones release. In in vitro and preclinical studies, curcumin was shown to induce GLP-1 secretion and improve postprandial glycemia. In humans, consumption of 220 mL turmeric-based beverage (TUR, containing 185 mg gallic acid equivalents (GAE)) prior to white wheat bread (WWB, 50 g available carbohydrate) reduced early postprandial glucose levels and induced peptide tyrosine⁻tyrosine (PYY) release, as well as lowered 'desire to eat' and 'prospective consumption' in a postprandial setting, compared to control. In the present study, 12 healthy participants (5 men, 7 women) were admitted. An identical beverage was given and consumed prior to isoenergetic (423 kcal) medium-fat (MF) or high-fat (HF) meals. Appetite sensations including perceived 'hunger', 'desire to eat', 'satiety', 'fullness', 'prospective consumption', and 'thirst' were measured using visual analogue scales. MF induced 18% (p = 0.039) higher 'satiety' compared to HF. TUR consumption prior to either MF or HF did not modulate the perceived appetite sensations. Whether macronutrient-induced appetite sensations override the actual turmeric effects warrants further investigation.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Nutrients
volume
11
issue
4
article number
736
pages
7 pages
publisher
MDPI AG
external identifiers
  • scopus:85064209870
  • pmid:30934903
ISSN
2072-6643
DOI
10.3390/nu11040736
language
English
LU publication?
yes
id
3f18b345-50f0-4bce-8570-130664838c6a
date added to LUP
2019-04-03 16:32:46
date last changed
2025-01-09 05:24:03
@article{3f18b345-50f0-4bce-8570-130664838c6a,
  abstract     = {{<p>The established effect of turmeric and its curcuminoids on appetite sensations was previously shown to be mediated by gut hormones release. In in vitro and preclinical studies, curcumin was shown to induce GLP-1 secretion and improve postprandial glycemia. In humans, consumption of 220 mL turmeric-based beverage (TUR, containing 185 mg gallic acid equivalents (GAE)) prior to white wheat bread (WWB, 50 g available carbohydrate) reduced early postprandial glucose levels and induced peptide tyrosine⁻tyrosine (PYY) release, as well as lowered 'desire to eat' and 'prospective consumption' in a postprandial setting, compared to control. In the present study, 12 healthy participants (5 men, 7 women) were admitted. An identical beverage was given and consumed prior to isoenergetic (423 kcal) medium-fat (MF) or high-fat (HF) meals. Appetite sensations including perceived 'hunger', 'desire to eat', 'satiety', 'fullness', 'prospective consumption', and 'thirst' were measured using visual analogue scales. MF induced 18% (p = 0.039) higher 'satiety' compared to HF. TUR consumption prior to either MF or HF did not modulate the perceived appetite sensations. Whether macronutrient-induced appetite sensations override the actual turmeric effects warrants further investigation.</p>}},
  author       = {{Zanzer, Yoghatama Cindya and Batista, Ângela Giovana and Dougkas, Anestis and Tovar, Juscelino and Granfeldt, Yvonne and Östman, Elin}},
  issn         = {{2072-6643}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{4}},
  publisher    = {{MDPI AG}},
  series       = {{Nutrients}},
  title        = {{Difficulties in Translating Appetite Sensations Effect of Turmeric-Based Beverage When Given Prior to Isoenergetic Medium- or High-Fat Meals in Healthy Subjects}},
  url          = {{http://dx.doi.org/10.3390/nu11040736}},
  doi          = {{10.3390/nu11040736}},
  volume       = {{11}},
  year         = {{2019}},
}