A prospective study on dietary fat and incidence of prostate cancer (Malmö, Sweden).
Wallström, Peter LU ; Bjartell, Anders LU ; Gullberg, Bo LU ; Olsson, Håkan LU
and Wirfält, Elisabet
LU
(2007)
In Cancer Causes and Control
18(10).
p.1107-1121
- Abstract
- To study the associations between intake of various types of fat and risk of prostate cancer (PCa) in a population-based cohort. We have studied 10,564 initially cancer-free men of the Malmo Diet and Cancer cohort, aged 45-73 years. Diet was assessed by a modified diet history method. Cases and clinical characteristics were ascertained via national and regional registry data. During a mean follow-up of 11.0 years, 817 incidental PCa cases were diagnosed. Out of these, 281 were classified as advanced. There were 202 cases occurring before 65 years of age. After adjustment for age and energy intake, there was no association between intake of any types of fat and risk of PCa, or between fat intake and advanced PCa or PCa occurring in persons... (More)
- To study the associations between intake of various types of fat and risk of prostate cancer (PCa) in a population-based cohort. We have studied 10,564 initially cancer-free men of the Malmo Diet and Cancer cohort, aged 45-73 years. Diet was assessed by a modified diet history method. Cases and clinical characteristics were ascertained via national and regional registry data. During a mean follow-up of 11.0 years, 817 incidental PCa cases were diagnosed. Out of these, 281 were classified as advanced. There were 202 cases occurring before 65 years of age. After adjustment for age and energy intake, there was no association between intake of any types of fat and risk of PCa, or between fat intake and advanced PCa or PCa occurring in persons aged < 65 years. However, we observed positive associations between intakes of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and risk of PCa. After adjustment for multiple confounders, the latter associations were weakened, but the results were otherwise virtually unchanged. This large study, with high-validity dietary data, does not support an association between intake of total, saturated, or mono-unsaturated fat and PCa risk. The observed associations between EPA/DHA intakes and PCa are difficult to interpret. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/606572
- author
- Wallström, Peter
LU
; Bjartell, Anders
LU
; Gullberg, Bo
LU
; Olsson, Håkan
LU
and Wirfält, Elisabet
LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- prostatic-neoplasms, dietary-fats, cohort-studies, fatty-acids
- in
- Cancer Causes and Control
- volume
- 18
- issue
- 10
- pages
- 1107 - 1121
- publisher
- Springer
- external identifiers
-
- wos:000249813500006
- scopus:34848815086
- pmid:17726648
- ISSN
- 1573-7225
- DOI
- 10.1007/s10552-007-9050-4
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Cancer Epidemiology (013007100), Emergency medicine/Medicine/Surgery (013240200), Pediatrics/Urology/Gynecology/Endocrinology (013240400), Division of Urological Cancers (013243420), Research group of Nutrition Epidemiology (013242550)
- id
- 72389179-780a-4d72-adcf-8c03c5137e44 (old id 606572)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17726648&dopt=Abstract
- date added to LUP
- 2016-04-01 11:39:35
- date last changed
- 2022-01-26 08:16:55
@article{72389179-780a-4d72-adcf-8c03c5137e44,
abstract = {{To study the associations between intake of various types of fat and risk of prostate cancer (PCa) in a population-based cohort. We have studied 10,564 initially cancer-free men of the Malmo Diet and Cancer cohort, aged 45-73 years. Diet was assessed by a modified diet history method. Cases and clinical characteristics were ascertained via national and regional registry data. During a mean follow-up of 11.0 years, 817 incidental PCa cases were diagnosed. Out of these, 281 were classified as advanced. There were 202 cases occurring before 65 years of age. After adjustment for age and energy intake, there was no association between intake of any types of fat and risk of PCa, or between fat intake and advanced PCa or PCa occurring in persons aged < 65 years. However, we observed positive associations between intakes of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and risk of PCa. After adjustment for multiple confounders, the latter associations were weakened, but the results were otherwise virtually unchanged. This large study, with high-validity dietary data, does not support an association between intake of total, saturated, or mono-unsaturated fat and PCa risk. The observed associations between EPA/DHA intakes and PCa are difficult to interpret.}},
author = {{Wallström, Peter and Bjartell, Anders and Gullberg, Bo and Olsson, Håkan and Wirfält, Elisabet}},
issn = {{1573-7225}},
keywords = {{prostatic-neoplasms; dietary-fats; cohort-studies; fatty-acids}},
language = {{eng}},
number = {{10}},
pages = {{1107--1121}},
publisher = {{Springer}},
series = {{Cancer Causes and Control}},
title = {{A prospective study on dietary fat and incidence of prostate cancer (Malmö, Sweden).}},
url = {{https://lup.lub.lu.se/search/files/2582698/626095.pdf}},
doi = {{10.1007/s10552-007-9050-4}},
volume = {{18}},
year = {{2007}},
}