Lund University Publications

@article{69a69ab5-013e-4c4c-ad31-a89b54e9b06f,
  abstract     = {{<p class="mb15"><b>Introduction:</b> The alarming global increase in <br>
lifestyle-related disorders such as obesity and type 2 diabetes mellitus<br>
 (T2DM) has increased during the last several decades. Poor dietary <br>
choices significantly contribute to this increase and prevention <br>
measures are urgently needed. Dietary intake of bioactive compounds <br>
found in foods are linked to a decrease likelihood of these disorders. <br>
For this purpose, a randomized crossover meal study was performed to <br>
compare the postprandial metabolic effects of lecithin and oat polar <br>
lipids in healthy subjects.</p><br>
<p class="mb15"><b>Materials and methods:</b> Eighteen young healthy <br>
subjects ingested test meals enriched with lecithin, oat polar lipids <br>
(PLs) or rapeseed oil. There were four test meals (i) 15 g oat polar <br>
lipids: OPL, (ii) 18 g sunflower lecithin (of which 15 g were polar <br>
lipids): LPL, (iii) 18 g rapeseed oil: RSO, and (iv) reference white <br>
wheat bread: WWB. Lipid-enriched test meals contained equivalent amounts<br>
 of total fat (18 g), and all breakfast meals contained 50 g available <br>
carbohydrates. The meals were served as breakfast followed by a <br>
standardised lunch (white wheat bread and meat balls) after 3.5 h. Test <br>
variables were measured at fasting and repeatedly during 5.5 h after <br>
ingestion of the breakfast.</p><br>
<p class="mb15"><b>Results:</b> Our study demonstrated that both LPL and<br>
 OPL had beneficial effects on postprandial glucose and insulin <br>
responses, and appetite regulating gut hormones, as compared to RSO and <br>
WWB. Significant increase in GLP-1, GIP, and PYY concentrations were <br>
seen after consuming breakfast meals with LPL and OPL, and ghrelin <br>
concentration was reduced compared to meals with RSO and WWB (<i>p</i> &lt; 0.05). Furthermore, triglycerides (TG) concentration was significantly reduced after OPL compared to RSO (<i>p</i> &lt; 0.05).<br>
 Our data show that there were no significant variations in glycaemic <br>
and insulin responses, TG, and gut hormone concentrations between LPL <br>
and OPL during breakfast (0–210 min) or over the whole study period <br>
(0–330 min).</p><br>
<p class="mb15"><b>Conclusion:</b> Our study revealed that the <br>
consumption of both lecithin and oat PLs included in breakfast meal may <br>
similarly enhance postprandial glucose tolerance, reduce TG, and enhance<br>
 the secretion of incretins and appetite regulating hormones in healthy <br>
young adults.</p>}},
  author       = {{Hossain, Mohammad Mukul and Tovar, Juscelino and Cloetens, Lieselotte and de Kam, Soraya and Nilsson, Anne}},
  issn         = {{2296-861X}},
  language     = {{eng}},
  publisher    = {{Frontiers Media S. A.}},
  series       = {{Frontiers in Nutrition}},
  title        = {{Oat polar lipids and sunflower lecithin similarly improve cardiometabolic risk markers and appetite controlling hormone responses after breakfast and a subsequent lunch. A randomized crossover study in healthy adults}},
  url          = {{http://dx.doi.org/10.3389/fnut.2024.1497844}},
  doi          = {{10.3389/fnut.2024.1497844}},
  volume       = {{11}},
  year         = {{2024}},
}