Division of Molecular Medicine and Gene Therapy
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- 2012
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Mark
Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo.
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- Contribution to journal › Article
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Mark
Progress towards Mechanism-Based Treatment for Diamond-Blackfan Anemia.
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- Contribution to journal › Article
- 2011
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Mark
Targeting Expression of the Leukemogenic PML-RAR alpha Fusion Protein by Lentiviral Vector-Mediated Small Interfering RNA Results in Leukemic Cell Differentiation and Apoptosis
(
- Contribution to journal › Article
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Mark
Regulation of morphogen signalling during neural patterning in the Xenopus embryo
(
- Thesis › Doctoral thesis (compilation)
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Mark
Efficient Generation of Hematopoietic Precursors and Progenitors From Human Pluripotent Stem Cell Lines.
(
- Contribution to journal › Article
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Mark
THE HYPOXIC HEMATOPOIETIC STEM CELL NICHE Consequences of Hypoxia-induced Transcription on Stem Cell Fate
(
- Thesis › Doctoral thesis (compilation)
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Mark
The role of Smad signaling in hematopoiesis and translational hematology.
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- Contribution to journal › Article
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Mark
Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications
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- Contribution to journal › Scientific review
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Mark
Dissociation of Bone Resorption and Bone Formation in Adult Mice with a Non-Functional V-ATPase in Osteoclasts Leads to Increased Bone Strength
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- Contribution to journal › Article
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Mark
Stress hematopoiesis requires Erg
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- Contribution to journal › Debate/Note/Editorial
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Mark
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
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- Contribution to journal › Article
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Mark
Proteasome Inhibition Improves the Muscle of Laminin {alpha}2 Chain Deficient Mice.
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- Contribution to journal › Article
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Mark
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
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- Contribution to journal › Scientific review
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Mark
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.
(
- Contribution to journal › Article
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Mark
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
(
- Contribution to journal › Article
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Mark
Successful management of a planned pregnancy in severe congenital thrombotic thrombocytopaenic purpura: the Upshaw-Schulman syndrome.
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- Contribution to journal › Article
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Mark
The Vascular Repair Process after Injury of the Carotid Artery is regulated by IL-1RI and MyD88 Signalling.
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- Contribution to journal › Article
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Mark
Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78.
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- Contribution to journal › Article
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Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
(
- Contribution to journal › Article
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Mark
Success Story of Targeted Therapy in Chronic Myeloid Leukemia: A Population-Based Study of Patients Diagnosed in Sweden From 1973 to 2008.
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- Contribution to journal › Article
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Mark
(H)if blood stem cells gO 2 sleep: What can wake them up?
(
- Contribution to journal › Article
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Mark
Joining the stem cell maintenance squad.
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- Contribution to journal › Article
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Mark
P4-09-02: G Protein-Coupled Estrogen Receptor 1 Positively Correlates with Estrogen Receptor a Expression and Increased Distant Disease-Free Survival of Breast Cancer Patients.
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- Contribution to journal › Published meeting abstract
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Mark
Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche.
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- Contribution to journal › Article
- 2010
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Mark
Development of Novel Therapies in Murine Models for Gaucher Disease
2010) 7th Annual Conference of the British-Society-for-Gene-Therapy In Human Gene Therapy 21(4). p.490-491(
- Contribution to journal › Published meeting abstract
-
Mark
A Human Model of IMO by Lentiviral Mediated shRNA Knock-down of Tcirg1 in CD34+Cells
2010) 18th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy In Human Gene Therapy 21(10). p.1458-1459(
- Contribution to journal › Published meeting abstract
-
Mark
In Vitro RNA Interference Screen for Regulators of Adhesion in Hematopoietic Stem/Progenitor Cells
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.256-256(
- Contribution to journal › Published meeting abstract
-
Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
(
- Contribution to journal › Published meeting abstract
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Mark
CCL28 Is a Growth Factor for Human Hematopoietic Stem- and Progenitor Cells
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.254-254(
- Contribution to journal › Published meeting abstract
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Mark
Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver
(
- Contribution to journal › Article
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Mark
Role of Biallelic C/EBPalpha Mutations and FLT-3 LTD in Initiation and Maintenance of AML
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.250-250(
- Contribution to journal › Published meeting abstract
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Mark
PIM1 kinase is destabilized by ribosomal stress causing inhibition of cell cycle progression
(
- Contribution to journal › Article
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Mark
Nonablative neonatal bone marrow transplantation rapidly reverses severe murine osteopetrosis despite low level engraftment and lack of selective expansion of the osteoclastic lineage.
(
- Contribution to journal › Article
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Mark
Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses
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- Contribution to journal › Article
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Mark
Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells
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- Contribution to journal › Article
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Mark
W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis.
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- Contribution to journal › Article
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Mark
Cripto Selectively Expands a Distinct Population of Hematopoietic Stem Cells Expressing the Cell Surface Receptor GRP78 and Strongly Induces An Immature Phenotype In Vivo After Ex Vivo Culture
(
- Contribution to journal › Published meeting abstract
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Mark
Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice
(
- Contribution to journal › Article
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Mark
High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event
(
- Contribution to journal › Published meeting abstract
-
Mark
The Success Story of Targeted Therapy In Chronic Myeloid Leukemia A Population Based Study of 3,173 Patients Diagnosed In Sweden 1973-2008
(
- Contribution to journal › Published meeting abstract
-
Mark
A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy
(
- Contribution to journal › Article
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Mark
SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation
(
- Contribution to journal › Published meeting abstract
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Mark
The Proportion of Ph+CD34(+)CD38(neg) Leukemic Stem Cells In the Bone Marrow of Newly Diagnosed Patients with Chronic Myeloid Leukemia (CML) In Chronic Phase (CP) Is Variable and Correlates with High Sokal Risk, High Leukocyte Count, Low Hemoglobin Concentration, Splenomegaly and Increased Hematological Toxicity During Initial TKI Therapy Data From a Randomized Phase II NordCML006 Study
(
- Contribution to journal › Published meeting abstract
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Mark
Cripto Selectively Expands a Distinct Population Of Hematopoietic Stem Cells Expressing Cell Surface Receptor GRP78
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.038-038(
- Contribution to journal › Published meeting abstract
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Mark
Second-Generation BCR-ABL Kinase Inhibitors in CML
(
- Contribution to journal › Letter
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Mark
Forward RNAi screens in human stem cells.
(
- Contribution to journal › Article
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Mark
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
(
- Contribution to journal › Article
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Mark
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
(
- Contribution to journal › Article
-
Mark
Genetic analysis of dasatinib-treated chronic myeloid leukemia rapidly developing into acute myeloid leukemia with monosomy 7 in Philadelphia-negative cells.
(
- Contribution to journal › Article
- 2009
-
Mark
Dissociation of bone resorption and bone formation in adult mice transplanted with OC/OC hematopoietic stem cells
(
- Contribution to journal › Published meeting abstract