Deniz Kirik

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2002
Mark Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
Georgievska, Biljana ^LU ; Kirik, Deniz ^LU and Björklund, Anders ^LU (2002) In Experimental Neurology 177(2). p.461-474
- Contribution to journal › Article
Mark Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer.
Kirik, Deniz ^LU ; Georgievska, Biljana ^LU ; Burger, Corinna ; Winkler, Christian ; Muzyczka, Nicholas ; Mandel, Ronald J and Björklund, Anders ^LU (2002) In Proceedings of the National Academy of Sciences 99(7). p.4708-4713
- Contribution to journal › Article
Mark Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease.
Lundblad, Martin ^LU ; Andersson, Malin ^LU ; Winkler, Christian ^LU ; Kirik, Deniz ^LU ; Wierup, Nils ^LU and Cenci Nilsson, Angela ^LU (2002) In European Journal of Neuroscience 15(1). p.120-132
- Contribution to journal › Article
Mark Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system
Kirik, Deniz ^LU ; Rosenblad, C ; Burer, C ; Lundberg, Cecilia ^LU ; Johansen, TE ; Muzyczka, N ; Mandel, RJ and Björklund, Anders ^LU (2002) In The Journal of Neuroscience 22(7). p.2780-2791
- Contribution to journal › Article
Mark Neuronal replacement from endogenous precursors in the adult brain after stroke.
Arvidsson, Andreas ^LU ; Collin, Tove ^LU ; Kirik, Deniz ^LU ; Kokaia, Zaal ^LU and Lindvall, Olle ^LU (2002) In Nature Medicine 8(9). p.963-970
- Contribution to journal › Article
2001
Mark Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease
Kirik, Deniz ^LU ; Georgievska, Biljana ^LU ; Rosenblad, Carl and Björklund, Anders ^LU (2001) In European Journal of Neuroscience 13(8). p.1589-1599
- Contribution to journal › Article
Mark Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration
Kirik, Deniz ^LU ; Winkler, Christian ^LU and Björklund, Anders ^LU (2001) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 21(8). p.2889-2896
- Contribution to journal › Article
Mark Restorative and neuroprotective treatment strategies for Parkinson’s disease: tudies on fetal dopamine cell transplants and GDNF delivery by intracerebral injections and recombinant AAV vectors.
Kirik, Deniz ^LU (2001)
- Thesis › Doctoral thesis (compilation)
2000
Mark Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
Kirik, Deniz ^LU ; Rosenblad, C and Björklund, Anders ^LU (2000) In European Journal of Neuroscience 12(11). p.3871-3882
- Contribution to journal › Article
Mark Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
Björklund, Anders ^LU ; Kirik, Deniz ^LU ; Rosenblad, C ; Georgievska, B ; Lundberg, Cecilia ^LU and Mandel, R J (2000) In Brain Research 886(1-2). p.82-98
- Contribution to journal › Article