Hakon Leffler
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- 2018
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Mark
Designing interactions by control of protein-ligand complex conformation : Tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions
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- Contribution to journal › Article
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Mark
Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function
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- Contribution to journal › Article
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Mark
Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain
(
- Contribution to journal › Article
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Mark
Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin–glycan specificities in a natural context
(
- Contribution to journal › Article
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Mark
The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin
(
- Contribution to journal › Article
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Mark
Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands
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- Contribution to journal › Article
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Mark
Galectins at a glance
(
- Contribution to journal › Article
- 2017
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Mark
Spindle pole cohesion requires glycosylation-mediated localization of NuMA
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- Contribution to journal › Article
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Mark
Galectin-3 inhibition by a small-molecule inhibitor reduces both pathological corneal neovascularization and fibrosis
(
- Contribution to journal › Article
- 2016
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Mark
Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3 '-sulfo-lactose, and 2 '-fucosyllactose
(
- Contribution to journal › Article
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Mark
Immunohistochemical Studies on Galectin Expression in Colectomised Patients with Ulcerative Colitis.
(
- Contribution to journal › Article
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Mark
Intra- and inter-molecular interactions of human galectin-3: assessment by full-assignment-based NMR.
(
- Contribution to journal › Article
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Mark
Galactose-amidine derivatives as selective antagonists of galectin-9
(
- Contribution to journal › Article
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Mark
Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3
(
- Contribution to journal › Article
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Mark
A Selective Galactose–Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model
(
- Contribution to journal › Article
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Mark
Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition
(
- Contribution to journal › Article
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Mark
Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C
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- Contribution to journal › Article
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Mark
Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans
(
- Contribution to journal › Article
- 2015
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Mark
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.
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- Contribution to journal › Article
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Mark
Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury
(
- Contribution to journal › Article
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Mark
Structural characterization of human galectin-4 C-terminal domain : Elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens
(
- Contribution to journal › Article
- 2014
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Mark
Synthesis of 1,2,3-triazole-linked galactohybrids and their inhibitory activities on galectins
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- Contribution to journal › Article
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Mark
Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists
(
- Contribution to journal › Article
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Mark
Primary and secondary glomerulonephritides 1.
2014) In Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 29 Suppl 3(May). p.186-200(
- Contribution to journal › Article
-
Mark
Design, synthesis, And applications of galectin modulators in human health
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
The role of Galectin-3 in α-synuclein-induced microglial activation
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- Contribution to journal › Scientific review
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Mark
Ligand binding and complex formation of galectin-3 is modulated by pH variations
(
- Contribution to journal › Article
- 2013
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Mark
Tuning the Preference of Thiodigalactoside- and Lactosamine-Based Ligands to Galectin-3 over Galectin-1
(
- Contribution to journal › Article
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Mark
Investigation into the Feasibility of Thioditaloside as a Novel Scaffold for Galectin-3-Specific Inhibitors
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- Contribution to journal › Article
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Mark
Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro
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- Contribution to journal › Article
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Mark
Galectin-3 guides intracellular trafficking of some human serotransferrin glycoforms
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- Contribution to journal › Article
- 2012
-
Mark
Glycosphingolipid composition of epithelial cells isolated along the villus axis of small intestine of a single human individual
(
- Contribution to journal › Article
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Mark
Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.
(
- Contribution to journal › Article
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Mark
Glycoproteomic identification of galectin-3 and -8 ligands in bronchoalveolar lavage of mild asthmatics and healthy subjects.
(
- Contribution to journal › Article
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Mark
Low-Molecular Weight Inhibitors of Galectins
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
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Mark
The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics
(
- Contribution to journal › Article
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Mark
Ligand induced galectin-3 self-association.
(
- Contribution to journal › Article
-
Mark
Regulation of Transforming Growth Factor-beta 1-driven Lung Fibrosis by Galectin-3
(
- Contribution to journal › Article
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Mark
Galectin-8 in IgA Nephritis: Decreased Binding of IgA by Galectin-8 Affinity Chromatography and Associated Increased Binding in Non-IgA Serum Glycoproteins.
(
- Contribution to journal › Article
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Mark
Galectin-3 endocytosis by carbohydrate independent and dependent pathways in different macrophage like cell types.
(
- Contribution to journal › Article
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Mark
Inhibition mechanism of human galectin-7 by a novel galactose- benzylphosphate inhibitor
(
- Contribution to journal › Article
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Mark
Taloside Inhibitors of Galectin-1 and Galectin-3
(
- Contribution to journal › Article
- 2011
-
Mark
Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.
(
- Contribution to journal › Article
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Mark
Synthesis of 3-amido-3-deoxy-beta-D-talopyranosides: all-cis-substituted pyranosides as lectin inhibitors
(
- Contribution to journal › Article
-
Mark
Inhibition of Galectins with Small Molecules
(
- Contribution to journal › Article
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Mark
Arene-anion based arginine-binding motif on a galactose scaffold : Structure-activity relationships of interactions with arginine-rich galectins
(
- Contribution to journal › Article
-
Mark
The anti-angiogenic peptide anginex greatly enhances Galectin-1 binding affinity for glycoproteins
(
- Contribution to journal › Article
- 2010
-
Mark
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
(
- Contribution to journal › Article
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Mark
Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3.
(
- Contribution to journal › Article
-
Mark
The inflammatory mediator galectin-3 is bound to phagocytes in circulation
(
- Contribution to journal › Published meeting abstract