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Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort

Zamora-Ros, R.; Knaze, V.; Lujan-Barroso, L.; Kuhnle, G. G. C.; Mulligan, A. A.; Touillaud, M.; Slimani, N.; Romieu, I.; Powell, N. and Tumino, R., et al. (2012) In European Journal of Clinical Nutrition 66(8). p.932-941
Abstract
BACKGROUND/OBJECTIVES: Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. SUBJECTS/METHODS: Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans,... (More)
BACKGROUND/OBJECTIVES: Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. SUBJECTS/METHODS: Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans, coumestans, enterolignans and equol) was compiled using data from available databases, in order to obtain and describe phytoestrogen intakes and their food sources across 27 redefined EPIC centres. RESULTS: Mean total phytoestrogen intake was the highest in the UK health-conscious group (24.9 mg/day in men and 21.1 mg/day in women) whereas lowest in Greece (1.3 mg/day) in men and Spain-Granada (1.0 mg/day) in women. Northern European countries had higher intakes than southern countries. The main phytoestrogen contributors were isoflavones in both UK centres and lignans in the other EPIC cohorts. Age, body mass index, educational level, smoking status and physical activity were related to increased intakes of lignans, enterolignans and equol, but not to total phytoestrogen, isoflavone or coumestan intakes. In the UK cohorts, the major food sources of phytoestrogens were soy products. In the other EPIC cohorts the dietary sources were more distributed, among fruits, vegetables, soy products, cereal products, non-alcoholic and alcoholic beverages. CONCLUSIONS: There was a high variability in the dietary intake of total and phytoestrogen subclasses and their food sources across European regions. (Less)
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published
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keywords
phytoestrogens, intake, food sources, EPIC-Europe
in
European Journal of Clinical Nutrition
volume
66
issue
8
pages
932 - 941
publisher
Nature Publishing Group
external identifiers
  • wos:000307236900010
  • scopus:84864840193
ISSN
1476-5640
DOI
10.1038/ejcn.2012.36
language
English
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yes
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08d1d2b5-8422-40a4-9734-d48ad110f1a7 (old id 3059530)
date added to LUP
2012-10-05 07:13:11
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2017-08-13 04:08:51
@article{08d1d2b5-8422-40a4-9734-d48ad110f1a7,
  abstract     = {BACKGROUND/OBJECTIVES: Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. SUBJECTS/METHODS: Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans, coumestans, enterolignans and equol) was compiled using data from available databases, in order to obtain and describe phytoestrogen intakes and their food sources across 27 redefined EPIC centres. RESULTS: Mean total phytoestrogen intake was the highest in the UK health-conscious group (24.9 mg/day in men and 21.1 mg/day in women) whereas lowest in Greece (1.3 mg/day) in men and Spain-Granada (1.0 mg/day) in women. Northern European countries had higher intakes than southern countries. The main phytoestrogen contributors were isoflavones in both UK centres and lignans in the other EPIC cohorts. Age, body mass index, educational level, smoking status and physical activity were related to increased intakes of lignans, enterolignans and equol, but not to total phytoestrogen, isoflavone or coumestan intakes. In the UK cohorts, the major food sources of phytoestrogens were soy products. In the other EPIC cohorts the dietary sources were more distributed, among fruits, vegetables, soy products, cereal products, non-alcoholic and alcoholic beverages. CONCLUSIONS: There was a high variability in the dietary intake of total and phytoestrogen subclasses and their food sources across European regions.},
  author       = {Zamora-Ros, R. and Knaze, V. and Lujan-Barroso, L. and Kuhnle, G. G. C. and Mulligan, A. A. and Touillaud, M. and Slimani, N. and Romieu, I. and Powell, N. and Tumino, R. and Peeters, P. H. M. and de Magistris, M. S. and Ricceri, F. and Sonestedt, Emily and Drake, Isabel and Hjartaker, A. and Skie, G. and Mouw, T. and Wark, P. A. and Romaguera, D. and Bueno-de-Mesquita, H. B. and Ros, M. and Molina, E. and Sieri, S. and Quiros, J. R. and Huerta, J. M. and Tjonneland, A. and Halkjaer, J. and Masala, G. and Teucher, B. and Kaas, R. and Travis, R. C. and Dilis, V. and Benetou, V. and Trichopoulou, A. and Amiano, P. and Ardanaz, E. and Boeing, H. and Foerster, J. and Clavel-Chapelon, F. and Fagherazzi, G. and Perquier, F. and Johansson, G. and Johansson, I. and Cassidy, A. and Overvad, K. and Gonzalez, C. A.},
  issn         = {1476-5640},
  keyword      = {phytoestrogens,intake,food sources,EPIC-Europe},
  language     = {eng},
  number       = {8},
  pages        = {932--941},
  publisher    = {Nature Publishing Group},
  series       = {European Journal of Clinical Nutrition},
  title        = {Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort},
  url          = {http://dx.doi.org/10.1038/ejcn.2012.36},
  volume       = {66},
  year         = {2012},
}